cjmr Güncel Tıbbi Araştırmaları Dergisi 2791-7061 Izmir Katip Celebi University 10.52818/cjmr.1870942 Nuclear Medicine Nükleer Tıp Galyum-68 DOTATATE PET/BT’de Metastazı Taklit Eden Vertebral Hemanjiomlar: Gastrik Nöroendokrin Tümörlü Bir Olgu Vertebral Hemangiomas Mimicking Metastases on Gallium-68 DOTATATE PET/CT: A Case of Gastric Neuroendocrine Tumor https://orcid.org/0009-0007-9628-0607 Ağartıoğlu Amine İrem IZMIR KATIP CELEBI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF NUCLEAR MEDICINE https://orcid.org/0000-0003-2535-7498 Küçüker Kadir Alper IZMIR KATIP CELEBI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF NUCLEAR MEDICINE https://orcid.org/0000-0002-6239-0660 Aksu Ayşegül IZMIR KATIP CELEBI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF NUCLEAR MEDICINE https://orcid.org/0000-0001-8163-2357 Atay Arif IZMIR KATIP CELEBI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF GENERAL SURGERY, GASTROENTEROLOGY SURGERY (MEDICINE) https://orcid.org/0000-0003-4861-5074 Turgut Bulent IZMIR KATIP CELEBI UNIVERSITY, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF NUCLEAR MEDICINE 04 29 2026 6 1 13 18 01 24 2026 03 30 2026 Copyright © 2021, Current Journal of Medical Research 2021 Current Journal of Medical Research

Ga-68 DOTATATE PET/BT, nöroendokrin tümörlerin (NET) evrelemesinde yüksek duyarlılığa sahip bir yöntemdir; ancak benign dokularda somatostatin reseptör ekspresyonu yanlış pozitif bulgulara ve tanısal tuzaklara yol açabilmektedir. Vertebral hemanjiomlar bu durumun nadir ancak klinik açıdan önemli nedenlerinden biridir. Bu yazıda, gastrik nöroendokrin tümör tanılı 77 yaşında bir erkek hastada servikal ve torakal vertebralarda izlenen fokal Ga-68 DOTATATE tutulumları sunulmaktadır. Önceden yapılmış bilgisayarlı tomografi (BT) ile korelasyon, bu lezyonların benign vertebral hemanjiomlar olduğunu ve tutulumun yanlış pozitif olduğunu göstermiştir. Bu olgu, Ga-68 DOTATATE PET/BT’de kemik tutulumlarının yorumlanmasında morfolojik görüntüleme yöntemleriyle korelasyonun önemini ve vertebral hemanjiomların ayırıcı tanıda mutlaka göz önünde bulundurulması gerektiğini vurgulamaktadır.

While the diagnostic efficacy of Ga-68 DOTATATE PET/CT for staging neuroendocrine tumors is well established, radiotracer accumulation in benign tissues may lead to false-positive findings and potential diagnostic pitfalls. Vertebral hemangiomas represent a rare but clinically important cause of such false-positive uptake. We report a 77-year-old male with a gastric neuroendocrine tumor who showed focal Ga-68 DOTATATE uptake in the cervical and thoracic vertebrae. Correlation with prior computed tomography (CT) demonstrated that these lesions were benign vertebral hemangiomas, indicating false-positive uptake. This case underscores the importance of correlating PET/CT findings with morphological imaging and considering vertebral hemangiomas in the differential diagnosis of bone uptake on Ga-68 DOTATATE PET/CT.

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