Behçet’s disease

Year 2011, Volume: 1 Issue: 1, 65 - 73, 31.01.2014

Emre Aytuğar Filiz Namdar Pekiner

Abstract

Behcet’s Disease (BD) is a chronic multisystem vascularinflammatory disorder, firstly described by the Turkish dermatologist Hulusi Behçet (1889-1948) in 1937. It is thought to be auto-immune and characterized by attacks of oral and genital ulcers, arthritis, cutaneous lesions, ocular lesions, involvement of the gastrointestinal tract and central nervous system. However the etiology of BD is still unknown, infectious, psychological, genetic and immunological factors can be counted as the possible etiologic factors. This review updates the BD in point of epidemiology, clinical symptoms, diagnosis, prognosis and etiopathology.

Key words: Behçet’s disease, epidemiology, etiopathology

Keywords

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Behçet hastalığı

Abstract

Behçet Hastalığı (BH) ilk olarak 1937 yılında Türk Dermatolog Hulusi Behçet (1889-1948) tarafından tanımlanan kronik vasküler- enflamatuar multisistemik bir hastalıktır. Oto-immün olduğu düşünülen hastalık, ataklarla seyreden oral ve genital aftlar, artrit, kutanöz lezyonlar, göz lezyonları, gastrointestinal sistem ve merkezi sinir sistem tutulumuyla karakterizedir. BH’nin etyolojisi günümüzde hala bilinmemekle birlikte olası etyolojik faktörler arasında enfeksiyöz, psikolojik, genetik ve immünolojik faktörler sayılabilmektedir. Bu derleme BH’yi epidemiyolojik, klinik belirtiler, diagnoz, prognoz ve etyopatogenetik bakımdan güncellemektedir.

Anahtar Kelimeler: Behçet hastalığı, epidemiyoloji, etyopatogenez

Keywords

Behçet hastalığı, epidemiyoloji, etyopatogenez

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