Adrenoleukodystrophy: Magnetic Resonance and Diffusion Weighted Imaging Findings

Year 2018, Volume: 40 Issue: 3, 308 - 311, 30.09.2018

Mehmet Atalar

https://doi.org/10.7197/223.vi.417858

Abstract

Adrenolökodistrofi: Manyetik Rezonans ve Difüzyon Ağırlıklı Görüntüleme
Bulguları

ÖZET

Adrenolökodistrofi (ALD), adrenal
korteks ve santral sinir sisteminin etkilendiği adrenal yetmezlik ve demiyelinasyona
bağlı nörolojik bulgularla seyreden nadir genetik bir hastalıktır. Bu
bozukluğun temel histopatolojik özellikleri, beyaz cevherde demiyelinasyon ve
aksonal kaybıdır. ALD gibi lökodistrofi tanısı alan hastalarda altta yatan
beyaz cevher anormalilerinin karakterizasyonu, lokalizasyonu ve ayırıcı
tanısında MRG öncelikli görüntüleme yöntemidir. Bu yazıda adrenolökodistrofi
tanısı alan 9 yaşındaki erkek olguda manyetik rezonans görüntüleme ve difüzyon
ağırlıklı görüntüleme bulgularının kliniğe katkısını sunmayı amaçladık.

 

Adrenoleukodystrophy: Magnetic
Resonance and Diffusion Weighted Imaging Findings

 

ABSTRACT

 

         Adrenoleukodystrophy (ALD) is
a rare genetic disorder characterized by adrenal failure affecting adrenal
cortex and central nervous system and demyelination-related neurological signs.
The basic histopathological properties of this disorder are white matter
demyelination and axonal loss. In patients diagnosed with a leukodystrophy such
as ALD, magnetic resonance imaging (MRI) is the primary imaging modality for
characterization, localization, and differential diagnosis of underlying white
matter abnormalities. Herein, we aimed to report the contribution of MRI and
diffusion-weighted imaging (DWI) findings to clinical findings of the disorder
in a 9-year-old boy diagnosed with adrenoleukodystrophy.

Keywords

Adrenoleukodystrophy, Brain, Diffusion-weighted imaging, Magnetic resonance imaging

References

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