Obstrüktif uyku apne sendromunun karotid arterler üzerine etkisi

Year 2010, Volume: 32 Issue: 3, 288 - 294, 03.02.2010

Emrah Güney Mübeccel Arslan İsmail Şalk Ömer Doğan İbrahim Akkurt

Abstract

Özet

Amaç. Bu çalışma obstrüktif uyku apne sendromunun (OUAS) karotid arterler üzerine olan etkilerini doğrudan gözlemek için planlanmıştır Yöntem. Çalısmaya uyku laboratuarında uyku testi yapılan 90 olgu (56 erkek, 34 kadın) dahil edildi. Olgular uyku testinde saptanan apne-hipopne indekslerine (AHİ) göre OUAS ve kontrol grubu olacak şekilde 2 gruba ayrıldı. Olguların ana karotid arterleri (AKA) ve internal karotid arterleri (İKA) Doppler ultrasonografi ile incelendi. Tüm damarların pik sistolik hız (PSH), end diyastolik hız (EDH), rezistif indeks (RI) ve lümen çapları ölçüldü, akım miktarları hesaplandı. AKA ve İKA intima-medya kalınlıkları (İMK) ölçüldü. Bulgular. AKA ve İKA İMK ortalamaları sırasıyla OUAS grubunda 0,82±0,1 mm, 0,62±0,1 mm; kontrol grubunda ise 0,69±0,1 mm, 0,51±0,08 mm olarak bulundu ve bu fark istatistiksel olarak önemliydi (p<0,05). Sonuç. Elde ettiğimiz veriler OUAS’ın karotid arterlerin İMK’sini arttırdığını, bunun da ateroskleroza zemin hazırladığını ortaya koymaktadır.

 

Anahtar sözcükler: uyku apnesi, karotid arter

 

Abstarct

Aim. This study is designed to evaluate the direct effects of obstructive sleep apnea syndrome (OSAS) on carotid artery. Method. Study population consisted of 90 patients (56 male, 34 female) who had been evaluated for OSAS by sleep study in sleep laboratory for suspected symptoms. Patients were classified into 2 groups according to the apnea-hypopnea index (AHİ) reflecting the severity of obstructive sleep apnea syndrome. The common carotid arteries (CCA) and internal carotid arteries (ICA) were examined using Doppler ultrasonography. Peak systolic velocity (PSV), end diastolic velocity (EDV), resistive index (RI), and luminal diameters of the vessels were measured, and flow volumes were calculated in all the arteries. The common and internal carotid arteries intima-media thickness (IMT) were measured. Results. The mean CCA and ICA IMT value were 0.82±0.1 mm, 0.62±0.1 mm in the OSAS patients; 0.69±0.1 mm, 0.51±0.08 mm in control patients. This differance was statistically significant (p<0.05). Conclusion. The result of our study, OSAS make increases at carotid artery intima-media thickness, atherosclerosis.

 

Key words: sleep apnea, carotid artery

Keywords

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Orijinal araştırma-Original research

Abstract

Amaç. Bu çalışma obstrüktif uyku apne sendromunun (OUAS) karotid arterler üzerine olan etkilerini doğrudan gözlemek için planlanmıştır Yöntem. Çalısmaya uyku laboratuarında uyku testi yapılan 90 olgu (56 erkek, 34 kadın) dahil edildi. Olgular uyku testinde saptanan apnehipopne indekslerine (AHİ) göre OUAS ve kontrol grubu olacak şekilde 2 gruba ayrıldı. Olguların ana karotid arterleri (AKA) ve internal karotid arterleri (İKA) Doppler ultrasonografi ile incelendi. Tüm damarların pik sistolik hız (PSH), end diyastolik hız (EDH), rezistif indeks (RI) ve lümen çapları ölçüldü, akım miktarları hesaplandı. AKA ve İKA intima-medya kalınlıkları (İMK) ölçüldü. Bulgular. AKA ve İKA İMK ortalamaları sırasıyla OUAS grubunda 0,82±0,1 mm, 0,62±0,1 mm; kontrol grubunda ise 0,69±0,1 mm, 0,51±0,08 mm olarak bulundu ve bu fark istatistiksel olarak önemliydi (p

Keywords

uyku apnesi, karotid arter

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