Correlation between dermatoscopic findings and histopathological subtypes of seborrheic keratosis

Year 2014, Volume: 36 Issue: 2, 157 - 166, 04.06.2014

Rukiye Yasak Melih Akyol Sedat Özçelik Sibel Berksoy Hayta Fahrettin Göze

https://doi.org/10.7197/cmj.v36i2.5000033998

Abstract

Aim. Seborrheic keratosis is a benign epidermal tumor, mostly seen in elderly. It has six histopatohological subtypes, including acantotic, hyperkeratotik, irritated, reticular, clonal type
and melanoacantoma. Dermatoscopy (epiluminisence microscopy) is an in vivo, noninvasive technique showing invisible morhological properties of pigmented skin lesions and tumors. The
aim of this study was to determine whether there is a correlation between dermatoscopic findings and histopathological subtypes of seborrheic keratosis.

Method. 80 lesions from 53 patients were included the study. Dermatoscopic findings of the lesions were defined. Incisional biopsy of 77 lesions and excisional bopsy of three lesions were taken and histopathological subtypes were determined.

Results. There was not a significant correlation between histopathological subtypes and some dermatoscopic findins, including comedo-like openings, milia-like cysts, fissures, polimorpheus vessels, dots/globules and blue-white structures (p>0.05). Sausage fingers were more frequent in hyperkeratotic irritated type of seborrheic keratosis (p<0.05). Milia-cloud was more frequent in irritated type, and pseudostreaks and pseudoreticular pattern was more frequent in reticular type of seborrheic keratosis (p<0.05).

Conclusion. Dermatoscopy as a diagnostic tool may be used for the identification of some histopathological subtypes of seborrheic keratosis. 

Keywords

Seborrheic keratosis, dermatoscopy, histopathologic type

Seboreik keratozun dermatoskopik görüntüleri ile histopatolojik alt tipleri arasında korelasyon

Abstract

Amaç. Seboreik keratoz daha çok yaşlılarda görülen benign karakterli epidermal bir tümördür. Akantotik, hiperkeratotik, irrite, retiküler, klonal tip ve melanoakantoma olmak üzere 6 farklı histopatolojik alt tipi vardır. Dermatoskopi (epiluminans mikroskopi) pigmente deri lezyonlarının çıplak göz ile görülemeyen klinik morfolojik özelliklerini gösteren in vivo, non-invaziv bir tekniktir. Bu çalışmadaki amacımız seboreik keratozun dermatoskopik özelliklerinin, histopatolojik alt grupları ile korelasyonu olup olmadığını saptamaktı.

Yöntem. Çalışmaya alınan 53 hastanın toplam 80 adet SK lezyonu alındı. Dermatoskopik bulgular tanımlandı. 77 lezyondan insizyonel biyopsi alınırken üç lezyona total rezeksiyon yapıldı ve histopatolojik alt tipler velirlendi.

Bulgular. SK alt tipleri; komedon benzeri açıklıklar, mila benzeri kistler, fissür, polimorf damar, ekzofitik papiller, dot/globül ve mavi beyaz yapı açısından değerlendirildiklerinde istatiksel olarak aralarındaki fark önemsiz bulunmuştur (p>0,05). Alt tiplerde sosis parmak hiperkeratotik tip ve irrite tip SK’da, milia-bulut irrite tip SK en fazla gözlenirken (p<0,05), psödostreaks ve psödoretiküler patern en çok retiküler tip SK’da saptanmıştır (p<0,05).

Sonuç. Dermatoskopi, seboreik keratoz olgularında histopatolojik alt tiplerin belirlenebilmesine yardımcı bir tanı aracı olarak kullanılabilir. 

Keywords

Seboreik keratoz, dermatoskopi, histopatolojik tip

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