Investigation of lactobacillus gasseri ma-2 as probiotic candidate

Year 2020, Volume: 41 Issue: 1, 228 - 234, 22.03.2020

Meltem Aşan Özüsağlam Ayşe Günyaktı

https://doi.org/10.17776/csj.654353

Abstract

Characterization of lactic acid bacteria in human milk has become an interesting field for developing new probiotics. Therefore, some probiotic properties of Lactobacillus gasseri MA-2 strain isolated before from human breast milk were screened in vitro. MA-2 strain exhibited safety aspects with no hemolytic activity (γ-hemolytic activity) and sensitivity to penicillin G, cloxacillin and chloramphenicol. The remarkable tolerance to various acid, bile, pepsin and pancreatin conditions was determined with high survival rate. The strain also presented significant auto-aggregation (93%) as well as co-aggregation activity with pathogenic microorganisms. L. gasseri MA-2 originated from human milk exhibited promising probiotic properties.

Keywords

probiotic, human milk, survival, gastrointestinal condition, aggregation

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