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Production cross-section and reaction yield of 82Sr for 82Sr/82Rb generator

Year 2022, Volume: 43 Issue: 4, 716 - 720, 27.12.2022
https://doi.org/10.17776/csj.1037539

Abstract

There are many radioisotopes used for diagnostic and therapeutic purposes in nuclear medicine. One of the radioisotopes used for diagnostic purposes is 82Rb. It is used in positron emission tomography (PET) as to be positron emitter and commonly obtained from 82Sr/82Rb generator. In this study, we have investigated some possible production mechanisms of 82Sr by regarding 82Sr/82Rb generator. 85,87Rb(p,xn)82Sr and 80,82,83,84,86Kr(3He,xn)82Sr reaction channels have been investigated using the CTFGM, BSFGM, and GSM models within the framework of TALYS nuclear reaction code. It has been seen that the production cross-sections, reaction yields and total activation values calculated up to 60 MeV beam energy value are in agreement with the available data in the literature.

References

  • [1] Gündoğdu E.A., Özgenç E., Ekinci M., Nükleer Tıpta Görüntüleme ve Tedavide Kullanılan Radyofarmasötikler, J Lit Pharm., 7 (1) (2018) 24-34.
  • [2] Azaam A., Excitation functions for proton-induced reactions on Te and natTi targets: Measurements and model calculations special relevant to the 128Te(p,n)128I reaction, Nuclear Physics A., 121790 (2020) 999.
  • [3] 82Sr Decay scheme, NOS. Available at: https://www.google.com/search?q=sr82+decay+scheme&rlz. Retrieved October 4, 2022.
  • [4] Aardenah K., van der Walt T.N., Davids C., Radiochemical separation of 82Sr and preparation of sterile 82Sr/82Rb generator columm, J. Radional Nucl. Chem., 270 (2006) 385-390.
  • [5] Hoffman I., Medical isotope production, research reactors and their contribution to the global xenon background, Journal of Radioanalytical and Nuclear Chemistry, 318 (2018) 165-173.
  • [6] Phillips D.R., Peterson E.J., Production of strontium-82 for the Cardiogen PET generator: a project of the Department of Energy Virtual Isotope Center, Radiochim. Acta., 88 (2000) 149-155.
  • [7] Horiguchi T., Nome H., Yoshizawa Y., Excitation functions of proton-induced nuclear reaction on 85Rb, J. Appl. Rad. Isot., 36 (1980) 141-151.
  • [8] Vereshchagin Yu.I., Zagryadskiy V.A., Prusakov V.N., Cyclotron 82Sr production for medical applications, Nuclear Instruments and Methods to Physics Research A., 334 (1993) 246-248.
  • [9] Kastleiner S., Qaim S.M., Nortier F., Excitation functions of 85Rb(p,xn)85m,g,83,82,81Sr reactions up to 100 MeV integral test of cross section data, comparison of production routes of 83Sr and thick target yield of 82Sr, Applied Radiation and Isotopes, 56 (2002) 685–695.
  • [10] Buthelezi E.Z., Nortier F.M., Schroeder I.W., Excitation functions fort the production of 82Sr by proton bombardment of natRb at energies up to 100 MeV, Applied Radiation and Isotopes, 64 (2006) 915-924.
  • [11] Deptula C., et al., Excitation functions and yields for medically important generators 82Sr-82Rb, 125Xe-123I and 201Bi-200Tl obtained with 100 MeV protons, Nukleonika, 35 (1-3) (1990) 3-22.
  • [12] Zagryadskii V.A., Latushkin S.T., Measurement of 82,83,84Kr(3He,xn)82Sr cross sections in kurchatov institute U-150 Cyclotron, Atomic Energy, 126 (2019) 5.
  • [13] Tarkanyi F., Hermanne A., Activation cross section data of deutron induced nuclear reactions on rubidium up to 50 MeV, Eur. Phys. J. A., (2021) 57-21.
  • [14] Zagryadskii V.A., Latushkin S.T., Experimental determination of 80,82,83Kr(α,xn)82Sr cross sections for reaction threshold to 60 MeV α-particles, Atomic Energy, 110 (2011) 2.
  • [15] Koning A., Hilare S., Goriely S., TALYS user manuel, 2015.
  • [16] Ignatyuk A.V., Istekov K.K., The role of collective effects in the systematics of nuclear level nensities, Yad. Fiz.,29(4) (1979) 875-883.
  • [17] Baba H., Nucl. Phys. A., A shell-model nuclear level density, 159(2) (1970) 625641.
  • [18] Ignatyuk A.V., Smirenkin G.N., Tishin A.S., Phenomenological description of energy dependence of the level density parameter, Sov. J. Nucl. Phys., 21 (1975) 255.
  • [19] Horiguchi T., Noma H.,Yoshizawa Y., Excitation functions of proton induced nuclear reactions on 85Rb, Internationel J. of Appl. rad. and Isotopes, 31 (1979) 141-151.
  • [20] Zeitseva N.G., et al., Cross section for the 100 MeV proton induced nuclearreactions and yields of some radionuclides used in nuclear medicine, Radiochimica Acta., 54 (1991) 57-72.
Year 2022, Volume: 43 Issue: 4, 716 - 720, 27.12.2022
https://doi.org/10.17776/csj.1037539

Abstract

References

  • [1] Gündoğdu E.A., Özgenç E., Ekinci M., Nükleer Tıpta Görüntüleme ve Tedavide Kullanılan Radyofarmasötikler, J Lit Pharm., 7 (1) (2018) 24-34.
  • [2] Azaam A., Excitation functions for proton-induced reactions on Te and natTi targets: Measurements and model calculations special relevant to the 128Te(p,n)128I reaction, Nuclear Physics A., 121790 (2020) 999.
  • [3] 82Sr Decay scheme, NOS. Available at: https://www.google.com/search?q=sr82+decay+scheme&rlz. Retrieved October 4, 2022.
  • [4] Aardenah K., van der Walt T.N., Davids C., Radiochemical separation of 82Sr and preparation of sterile 82Sr/82Rb generator columm, J. Radional Nucl. Chem., 270 (2006) 385-390.
  • [5] Hoffman I., Medical isotope production, research reactors and their contribution to the global xenon background, Journal of Radioanalytical and Nuclear Chemistry, 318 (2018) 165-173.
  • [6] Phillips D.R., Peterson E.J., Production of strontium-82 for the Cardiogen PET generator: a project of the Department of Energy Virtual Isotope Center, Radiochim. Acta., 88 (2000) 149-155.
  • [7] Horiguchi T., Nome H., Yoshizawa Y., Excitation functions of proton-induced nuclear reaction on 85Rb, J. Appl. Rad. Isot., 36 (1980) 141-151.
  • [8] Vereshchagin Yu.I., Zagryadskiy V.A., Prusakov V.N., Cyclotron 82Sr production for medical applications, Nuclear Instruments and Methods to Physics Research A., 334 (1993) 246-248.
  • [9] Kastleiner S., Qaim S.M., Nortier F., Excitation functions of 85Rb(p,xn)85m,g,83,82,81Sr reactions up to 100 MeV integral test of cross section data, comparison of production routes of 83Sr and thick target yield of 82Sr, Applied Radiation and Isotopes, 56 (2002) 685–695.
  • [10] Buthelezi E.Z., Nortier F.M., Schroeder I.W., Excitation functions fort the production of 82Sr by proton bombardment of natRb at energies up to 100 MeV, Applied Radiation and Isotopes, 64 (2006) 915-924.
  • [11] Deptula C., et al., Excitation functions and yields for medically important generators 82Sr-82Rb, 125Xe-123I and 201Bi-200Tl obtained with 100 MeV protons, Nukleonika, 35 (1-3) (1990) 3-22.
  • [12] Zagryadskii V.A., Latushkin S.T., Measurement of 82,83,84Kr(3He,xn)82Sr cross sections in kurchatov institute U-150 Cyclotron, Atomic Energy, 126 (2019) 5.
  • [13] Tarkanyi F., Hermanne A., Activation cross section data of deutron induced nuclear reactions on rubidium up to 50 MeV, Eur. Phys. J. A., (2021) 57-21.
  • [14] Zagryadskii V.A., Latushkin S.T., Experimental determination of 80,82,83Kr(α,xn)82Sr cross sections for reaction threshold to 60 MeV α-particles, Atomic Energy, 110 (2011) 2.
  • [15] Koning A., Hilare S., Goriely S., TALYS user manuel, 2015.
  • [16] Ignatyuk A.V., Istekov K.K., The role of collective effects in the systematics of nuclear level nensities, Yad. Fiz.,29(4) (1979) 875-883.
  • [17] Baba H., Nucl. Phys. A., A shell-model nuclear level density, 159(2) (1970) 625641.
  • [18] Ignatyuk A.V., Smirenkin G.N., Tishin A.S., Phenomenological description of energy dependence of the level density parameter, Sov. J. Nucl. Phys., 21 (1975) 255.
  • [19] Horiguchi T., Noma H.,Yoshizawa Y., Excitation functions of proton induced nuclear reactions on 85Rb, Internationel J. of Appl. rad. and Isotopes, 31 (1979) 141-151.
  • [20] Zeitseva N.G., et al., Cross section for the 100 MeV proton induced nuclearreactions and yields of some radionuclides used in nuclear medicine, Radiochimica Acta., 54 (1991) 57-72.
There are 20 citations in total.

Details

Primary Language English
Subjects Classical Physics (Other)
Journal Section Natural Sciences
Authors

Şevki Şentürk 0000-0001-8355-1307

Tuncay Bayram 0000-0003-3704-0818

Serkan Akkoyun 0000-0002-8996-3385

Publication Date December 27, 2022
Submission Date February 11, 2022
Acceptance Date October 10, 2022
Published in Issue Year 2022Volume: 43 Issue: 4

Cite

APA Şentürk, Ş., Bayram, T., & Akkoyun, S. (2022). Production cross-section and reaction yield of 82Sr for 82Sr/82Rb generator. Cumhuriyet Science Journal, 43(4), 716-720. https://doi.org/10.17776/csj.1037539