The Effect of Platelet-Rich Fibrin and Titanium Prepared Platelet-Rich Fibrin on Early Soft Tissue Healing of Extraction Sites

Year 2018, Volume: 21 Issue: 4, 304 - 310, 30.12.2018

Esra Ercan

https://doi.org/10.7126/cumudj.471947

Cited By: 3

Abstract

Objective: Physiological changes start after
tooth extraction. Some post-operative symptoms may accompany this healing
period, and affect patient's life quality. Many techniques have been developed
to promote healing soft and hard tissue and improve patient's life quality. So,
the aim of this study was to compare the early soft tissue healing of
extraction sites treated with leucocyte-platelet rich fibrin (L-PRF), titanium
prepared platelet rich fibrin (T-PRF) and non-treated control sites.

Material&Methods:A total of
42 single root teeth were enrolled to study. Extraction site was treated by
L-PRF or T-PRF. Spontanous healing sockets were considered as control sites. Landy
Wound Healing Index (LWH) scores and H₂O₂ bubbling test
results for complete wound epithelization (CWE) were recorded at 1^st
and 2^nd week. Also, the patient was requested to record the VAS scale
and the number of analgesics that taken during two days after extraction.

Results: The LWH were statistically significantly improved for all
groups at 2^nd week according to 1^st week (p<0.05). However there was no
difference among three groups in each week. According to H₂O₂
bubbling test results, the
CWE ratio at 1st week was 7.1%, 53,3% and 69.2% of control, L-PRF and T-PRF
groups, respectively. The control group rate of CWE was statistically
significantly lower than both of the test groups (p<0.05). Both of the test groups at 2^nd week showed
100% CWE, however this rate was only 35.7% of control group. The VAS score, at
1^st day,  was statistically
significantly higher at control group than both of the test groups at first day
(p<0.05). There was
non-significant difference among groups at 2nd day. There wass also
non-significant difference among groups with regard to number of analgesics.

Conclusion:
Both T-PRF and L-PRF, which are completely autologous biomaterials, enhance
wound epithelzation and reduced post-op discomfort at extraction sockets.

Keywords

tooth extraction, platelet-rich fibrin, wound healing

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