Year 2019, Volume 22 , Issue 4, Pages 469 - 476 2019-12-29

Comparison of Mineral Trioxide Uggregate, EndoSequence Root Repair Material, and Biodentine Used for Repairing Root Perforations: A Systematic Review.

Faisal ALGHAMDİ [1] , Esraa ALJAHDALİ [2]

he root perforation, in spite of being taken as a challenging accident in root canal treatment, has to offer favorable results when exposed to appropriate therapeutic conduct and the usage of materials that have convenient properties. The aim of the current review is to collect all updated and available studies including imperative information concerning the use of Mineral trioxide aggregate, EndoSequence root repair material and Biodentine in the treatment of root perforation approaching some of the key properties for treatment success. A search was performed in the two automated databases (Google Scholar and PubMed use English-language literature) for this systematic review, using specific inclusion and exclusion criteria and keywords. The electronic search was done in December 2018 and update in June 2019. Our inquiry uncovered Twenty-two studies that met the exclusion and inclusion criteria. These studies investigated the use of MTA, EndoSequence ERRM and Biodentine in the root perforation that happened during the endodontic treatment. It was confirmed that there is no unanimity in this review concerning the material that shows the best characteristics, once none of the materials discussed had all the major properties higher than the others, this way it is required the enforcement of further studies aimed at selecting the best characteristics of the material suggested in the root perforation treatment.

root canal filling materials, mineral trioxide aggregate, EndoSequence root repair material, tooth root
  • 1. Apostolska, S., et al., Biodentinetm as a furcal perforation repair material: A case series. Medicinski pregled, 2017. 70(7-8): p. 223-225.
  • 2. Silva, L.A.B., et al., Furcation perforation: periradicular tissue response to Biodentine as a repair material by histopathologic and indirect immunofluorescence analyses. Journal of endodontics, 2017. 43(7): p. 1137-1142.
  • 3. Tabassum, S. and F.R. Khan, Failure of endodontic treatment: The usual suspects. European journal of dentistry, 2016. 10(1): p. 144.
  • 4. Silvestre, A., et al., FURCAL DRILLING TREATMENT: CASE REPORT. . Catholic Academic Day of the Academics, 2017. 2(1).
  • 5. Haghgoo, R., et al., An in vitro comparison of furcal perforation repaired with pro-root MTA and new endodontic cement in primary molar teeth-a microleakage study. Journal of Dentistry, 2014. 15(1): p. 28.
  • 6. Azim, A.A., A. Lloyd, and G.T.-J. Huang, Management of longstanding furcation perforation using a novel approach. Journal of endodontics, 2014. 40(8): p. 1255-1259.
  • 7. Kaushik, A., et al., Management of iatrogenic root perforation with pulp canal obliteration. Saudi Endodontic Journal, 2014. 4(3): p. 141.
  • 8. Lagisetti, A.K., P. Hegde, and M.N. Hegde, Evaluation of bioceramics and zirconia-reinforced glass ionomer cement in repair of furcation perforations: An in vitro study. J Conserv Dent, 2018. 21(2): p. 184-189.
  • 9. Cosme-Silva, L., et al., Radicular perforation repair with mineral trioxide aggregate: a case report with 10-year follow-up. The open dentistry journal, 2016. 10: p. 733.
  • 10. Jeevani, E., et al., Evaluation of sealing ability of MM-MTA, Endosequence, and biodentine as furcation repair materials: UV spectrophotometric analysis. Journal of conservative dentistry: JCD, 2014. 17(4): p. 340.
  • 11. Kerner, S. and F. Bronnec, Conservative treatment of a large facial midroot perforation. Case reports in dentistry, 2015. 2015: p. 326302.
  • 12. Singla, M., et al., Comparison of push-out bond strength of furcation perforation repair materials–Glass ionomer cement Type II, hydroxyapatite, mineral trioxide aggregate, and biodentine: An in vitro study. Contemporary clinical dentistry, 2018. 9(3): p. 410.
  • 13. Cardoso, M., et al., Biodentine for Furcation Perforation Repair: An Animal Study with Histological, Radiographic and Micro-Computed Tomographic Assessment. Iranian endodontic journal, 2018. 13(3): p. 323.
  • 14. Silveira, A.M.V., et al., Repair of root perforation using the mineral trioxide aggregate. REVISTA DO CROMG, 2015. 16(1): p. 41-44.
  • 15. Melo, P.A.V., et al., Cervical root perforation: report of a clinical case. Revista de Odontologia da Universidade Cidade de São Paulo, 2017. 23(3): p. 266-272.
  • 16. Zaccara, I.M., et al., Treatment of a complex furcal perforation: case report. . Brazilian Journal of Periodontology, 2014. 24(1): p. 54-59.
  • 17. Taha, N.A., R.A. Safadi, and M.S. Alwedaie, Biocompatibility evaluation of EndoSequence root repair paste in the connective tissue of rats. Journal of endodontics, 2016. 42(10): p. 1523-1528.
  • 18. Mancino, D., F. Meyer, and Y. Haikel, Improved single visit management of old infected iatrogenic root perforations using Biodentine®. Giornale italiano di endodonzia, 2018. 32(1): p. 17-24.
  • 19. Solanki, N.P., K.K. Venkappa, and N.C. Shah, Biocompatibility and sealing ability of mineral trioxide aggregate and biodentine as root-end filling material: A systematic review. Journal of conservative dentistry: JCD, 2018. 21(1): p. 10.
  • 20. Sinkar, R.C., et al., Comparison of sealing ability of ProRoot MTA, RetroMTA, and Biodentine as furcation repair materials: An ultraviolet spectrophotometric analysis. J Conserv Dent, 2015. 18(6): p. 445-8.
  • 21. Dorileo, M.C.G.O., et al., Comparative analysis of physicochemical properties of root perforation sealer materials. Restorative dentistry & endodontics, 2014. 39(3): p. 201-209.
  • 22. Loushine, B.A., et al., Setting properties and cytotoxicity evaluation of a premixed bioceramic root canal sealer. J Endod, 2011. 37(5): p. 673-7.
  • 23. Shokouhinejad, N., et al., Effect of acidic environment on dislocation resistance of endosequence root repair material and mineral trioxide aggregate. Journal of dentistry (Tehran, Iran), 2014. 11(2): p. 161.
  • 24. Aggarwal, V., et al., Marginal Adaptation Evaluation of B iodentine and MTA P lus in “Open Sandwich” Class II Restorations. Journal of Esthetic and Restorative Dentistry, 2015. 27(3): p. 167-175.
  • 25. Yoldaş, S.E., et al., Comparison of the potential discoloration effect of bioaggregate, biodentine, and white mineral trioxide aggregate on bovine teeth: in vitro research. Journal of endodontics, 2016. 42(12): p. 1815-1818.
  • 26. Deepthi, V., et al., Effect of acidic pH on microhardness and microstructure of theraCal LC, endosequence, mineral trioxide aggregate, and biodentine when used as root repair material. Journal of conservative dentistry: JCD, 2018. 21(4): p. 408.
  • 27. Samyuktha, V., et al., Cytotoxicity evaluation of root repair materials in human-cultured periodontal ligament fibroblasts. J Conserv Dent, 2014. 17(5): p. 467-70.
  • 28. Ramazani, N. and P. Sadeghi, Bacterial Leakage of Mineral Trioxide Aggregate, Calcium-Enriched Mixture and Biodentine as Furcation Perforation Repair Materials in Primary Molars. Iran Endod J, 2016. 11(3): p. 214-8.
  • 29. Rifaey, H.S., et al., Comparison of the Osteogenic Potential of Mineral Trioxide Aggregate and Endosequence Root Repair Material in a 3-dimensional Culture System. J Endod, 2016. 42(5): p. 760-5.
  • 30. Bampa, J.U., et al., Analysis of the sealing ability of Portland cement and mineral trioxide aggregate in molars furcation perforations. Revista Odonto Ciência, 2015. 30(3): p. 85-90.
  • 31. El-Khodary, H.M., et al., Sealing Ability of Four Calcium Containing Cements used for Repairing Furcal Perforations in Primary Molars: An in vitro study. J Contemp Dent Pract, 2015. 16(9): p. 733-9.
  • 32. Alsulaimani, R.S., Immediate and Delayed Repair of 2 Sizes of Furcal Perforations in Dogs' Teeth Using Mineral Trioxide Aggregate Cement. Journal of endodontics, 2018. 44(6): p. 1000-1006.
  • 33. Krupp, C., et al., Treatment outcome after repair of root perforations with mineral trioxide aggregate: a retrospective evaluation of 90 teeth. J Endod, 2013. 39(11): p. 1364-8.
  • 34. Guneser, M.B., M.B. Akbulut, and A.U. Eldeniz, Effect of various endodontic irrigants on the push-out bond strength of biodentine and conventional root perforation repair materials. J Endod, 2013. 39(3): p. 380-4.
  • 35. Mente, J., et al., Treatment outcome of mineral trioxide aggregate: repair of root perforations. J Endod, 2010. 36(2): p. 208-13.
  • 36. Pace, R., V. Giuliani, and G. Pagavino, Mineral trioxide aggregate as repair material for furcal perforation: case series. J Endod, 2008. 34(9): p. 1130-3.
  • 37. Guo, Y.-j., et al., Physical properties and hydration behavior of a fast-setting bioceramic endodontic material. BMC oral health, 2016. 16(1): p. 23.
  • 38. Wang, Z., et al., Acidic pH weakens the microhardness and microstructure of three tricalcium silicate materials. International endodontic journal, 2015. 48(4): p. 323-332.
Primary Language en
Subjects Health Care Sciences and Services
Journal Section Review

Orcid: 0000-0003-2086-0772
Author: Faisal ALGHAMDİ (Primary Author)
Institution: Faculty of Dentistry, King Abdulaziz University
Country: Saudi Arabia

Orcid: 0000-0002-2530-3054
Author: Esraa ALJAHDALİ
Institution: Faculty of Dentistry, King Abdulaziz University
Country: Saudi Arabia


Application Date : July 9, 2019
Acceptance Date : September 12, 2019
Publication Date : December 29, 2019

EndNote %0 Cumhuriyet Dental Journal Comparison of Mineral Trioxide Uggregate, EndoSequence Root Repair Material, and Biodentine Used for Repairing Root Perforations: A Systematic Review. %A Faisal Alghamdi , Esraa Aljahdali %T Comparison of Mineral Trioxide Uggregate, EndoSequence Root Repair Material, and Biodentine Used for Repairing Root Perforations: A Systematic Review. %D 2019 %J Cumhuriyet Dental Journal %P 1302-5805-2146-2852 %V 22 %N 4 %R doi: 10.7126/cumudj.589413 %U 10.7126/cumudj.589413