Agenesis of Frontal Sinuses in Association with Kindler Syndrome: A Rare Case Report Running title: Agenesis of frontal sinuses in Kindler Syndrome

Year 2020, Volume: 23 Issue: 2, 149 - 152, 30.06.2020

Ali Bagherpour Shahin Moeını

Abstract

Kindler syndrome, as a rare subtype of Epidermolysis Bullosa, sets
in motion a series of genetic conditions causing minor traumas and blisters on
skin and making the skin susceptible to sunburn. The present study presented a
case report of a 32-year-old female diagnosed with Kindler syndrome. Coronal
and axial cone-beam computed tomography (CBCT) images clearly exhibited the agenesis
of frontal sinuses. The condition was completely obvious in the images, which
is a rare occurrence and has not been previously reported. The underdevelopment
or aplasia of the paranasal sinuses is a rare phenomenon, which relates primarily
to the frontal sinuses (12%) and secondarily to the maxillary sinuses (5-6%). Similarly,
the agenesis of the sphenoid sinuses is an extremely rare condition. Therefore,
raising our awareness about the paranasal sinus anomalies associated with the Kindler
syndrome can lead to new discoveries about this syndrome. Further, with respect
to the other patients suffering from Kindler syndrome, obtaining the basis of such
knowledge together with evaluating CBCT or CT images in order to detect
abnormalities can facilitate the management of the problems arising from paranasal
sinus abnormalities.

Keywords

Frontal sinus, Epidermolysis Bullosa, Syndrome

Supporting Institution

Mashhad University of Medical Sciences

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