A Study on Antimicrobial and Antioxidant Activities of Cyclamen coum, Colchicum turcicum and Colchicum bornmuelleri Species

Year 2020, Volume: 3 Issue: 2, 121 - 127, 24.12.2020

Fatih Özcan , Alican Bahadır Semerci , Kenan Tunç

Abstract

In this study, antimicrobial effects of Cyclamen coum, Colchicum bornmuelleri and Colchicum turcicum extracts prepared with ethanol against B. subtilis ATCC 6633, E. faecalis ATCC 29212, E. coli ATCC 25922, S. epidermidis ATCC 12228, S.typhimurium ATCC 14028, P. aeruginosa ATCC 27853, C. albicans ATCC 1029 and S. aureus ATCC 29213 microorganism were investigated by using disk diffusion method. In additon, DPPH scavening activities, antioxidant activities and total phenolic content were determined with Folin-Ciocalteu method. It was determined that extracts obtained Cyclamen coum plant showed moderate antifungal activity on Candida albicans. It has been determined that aerial extracts of Colchicum bornmuelleri and Colchicum turcicum plants have antibacterial effects on E. faecalis. These extracts did not showed antibacterial activty on other test microorganisms.The highest and lowest antioxidant activity results (IC50 values) obtained from the extracts were determined as Colchicum turcicum aerial parts 14.2 µg/mL, Colchicum bornmuelleri aerial parts 768,65 µg/mL. When the extracts used in this study were compared with the standart antioxidant ascorbic acid, it was found that the aboveground extracts of C. bornmuelleri and C. turcicum showed high antioxidant activity. The total amounts of phenolic substances was determined as 191,85 mg GA/100g in the extracts obtained from the aerial part of the C. bornmuelleri plant.

Keywords

Colchicum turcicum,, Cylamen coum,, Colchicum bornmuelleri,, antioxidant

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