An Overview and Renewed Emphasis on Ethnopharmacology of Rosemary (Salvia Rosmarinus)

Year 2022, Volume: 5 Issue: 1, 74 - 85, 30.06.2022

Flavien Shimira Ghassan Zahıd Fildaus Nyırahabımana

https://doi.org/10.38093/cupmap.1098392

Cited By: 1

Abstract

Medicinal herbs have been employed to treat a wide range of illnesses and as an approach to maintain excellent health since ancient times. Substantially, their efficacies have been methodically investigated to guarantee the high standards of medicinal plant-derived products. This review focuses on Rosemary (Salvia Rosmarinus), formerly referred as Rosmarinus officinalis, an aromatic evergreen shrub in the Lamiaceae family. Our goal is to compile all ethnobotanical applications of the herb, as well as relevant phytoconstituent, in vivo, and in vitro studies, and to thoroughly outline its potential use in contemporary herbal-based medicine. Using popular search engines, multiple sources were successfully identified. Moreover, the search for published materials such as books, articles, and conference proceedings from today to the previous eras was prioritized. The most notable findings about this herb's ethnopharmacological actions include the inhibition of Dipeptidyl Peptidase (DPP-4), the most pertinent enzyme in Type 2 Diabetes Mellitus (T2DM), as well as its anticancer activity, particularly the overall inhibition actions of its active compounds on endothelium and cancer cell proliferation. In a broad sense, it is a good medicinal plant with a lot of potential for improving human health.

Keywords

Anticancer, anti-inflammatory, antimicrobial, antioxidant, hepatoprotective, phenolic compounds

Supporting Institution

None

Project Number

None

References

• Abers, M., Schroeder, S., Goelz, L., Sulser, A., St. Rose, T., Puchalski, K., & Langland, J., (2021). Antimicrobial activity of the volatile substances from essential oils. BMC Complementary Medicine and Therapies, 21, 124. https://doi.org/10.1186/s12906-021-03285-3
• Allegra, A., Tonacci, A., Pioggia, G., Musolino, C., & Gangemi, S., (2020). Anticancer activity of Rosmarinus officinalis L.: Mechanisms of action and therapeutic potentials. Nutrients, 12(6), 1739. https://doi.org/10.3390/nu12061739
• Andrade, J.M., Faustino, C., Garcia, C., Ladeiras, D., Reis, C.P., & Rijo, P., (2018). Rosmarinus officinalis L.: An update review of its phytochemistry and biological activity. Future Science OA, 4(4), FSO283. https://doi.org/10.4155/fsoa-2017-0124
• Bakırel, T., Bakırel, U., Keleş, O.Ü., Ülgen, S.G., & Yardibi, H., (2008). In vivo assessment of antidiabetic and antioxidant activities of rosemary (Rosmarinus officinalis) in alloxan-diabetic rabbits. Journal of Ethnopharmacology, 116(1), 64–73. https://doi.org/10.1016/j.jep.2007.10.039