Background: Smoking is a prevalent habit associated with numerous health risks, including various cancers, cardiovascular diseases, respiratory disorders, and diabetes. Methods: According to the Lifestyle Medicine outcomes of second-grade medical students’ curriculum, this case report describes the smoking cessation journey of a 39-year-old woman who has been smoking since she was 17. Results: The participant's motivation to quit smoking stemmed from factors such as rising cigarette prices, concerns about the health of her family members, and fear of developing various smoking-related diseases. Despite several attempts to quit smoking in the past, she struggled to maintain abstinence for longer durations. This report highlights the challenges faced by the participant, including the experience of weight gain during previous quit attempts and the lack of professional support. The role of social and environmental factors, such as her husband's smoking habits and her child's exposure to secondhand smoke, is also discussed.Conclusion: Professional assistance, behavioral interventions, and strategies targeting triggers associated with alcohol and coffee consumption may contribute to successful smoking cessation. A holistic approach and patient-family centeredness could be critical factors in achieving the LSM process for quitting tobacco usage.