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A Case of Autoimmune Hepatitis Presenting with Fever and Bicytopenia

Year 2022, Volume: 2 Issue: 1, 24 - 27, 29.01.2022

Abstract

Autoimmune hepatitis is a chronic inflammatory liver disease of unknown cause. In the etiology, genetic predisposition and triggering factors such as viruses (hepatitis A, hepatitis B, hepatitis C, Ebstein Bar virus, cytomegalovirus), bacteria, drugs (propylthiouracil, nitrofurantoin, isoniazid, etc.) are emphasized. Cases may be asymptomatic or present with complaints such as fatigue, weakness, jaundice, upper abdominal discomfort, pruritis, loss of appetite, nausea and fever. We presented a case of autoimmune hepatitis presenting with fever and bisitopenia.

Project Number

YOK

References

  • 1. Edward L. Krawitt, M.D., Autoimmune hepatitis. N.Engl. J. Med. 2006;354:54-66.
  • 2. Mc Farlane IG. Pathogenesis of autoimmune hepatitis. Biomed Pharmacother 1999;53(5-6): 255-63.
  • 3. Manns MP, Strassburg CP. Autoimmune hepatitis; Clinical challenges. Gastroenterelogy 2001;120: 1502-17.
  • 4. Ökten A, Demir S, Kaymakoğlu S, Çakaloğlu Y, Dinçer D, Beşışık F. Kronik hepatitlerin etiyolojik dağılımı. 14. Ulusal Gastroentereloji Kong. 28 Eylül-3 Ekim 1997, Merin. TJ Gastroenterol 1997, 8 (supll 1): A24.
  • 5. Alvarez F, Berg PA, Bianchi FB, et al. International Autoimmune Hepatitis Group report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999;31:929-38.
  • 6. David H. Alpers, Autoimmune hepatitis, Gastroenterology Lippincott Williams Wilkins,2002, s.565.
  • 7. Teufel A, Gale PR, Kanzler S. Update on autoimmune hepatitis. World J Gastroenterol 2009;15:1035-41.
  • 8. Sherlock S, Dooley J. Chronic autoimmune hepatitis. In: Diseases of the Liver and Biliary System 10th edn. Oxford Blackwell : London, 1993: 308-15.
  • 9. Kaymakoğlu S. Otoimmun hepatit. Türkiye Klinikleri J Int Med Sci 2006;2:48-53.
  • 10. McFarlane IG. Autoimmune hepatitis; clinical manifestations and diagnostic criteria. Can J Gastroenterol 2001;15:107-13.
  • 11. Johnson PJ, McFarlane IG. Meeting report: International Autoimmune Hepatitis Group. Hepatology 1993;18:998-1005.
  • 12. Medina J, Garcia-Buey L, Moreno-Otero R. Review article: Immunopathogenetic and therapeutic aspects of autoimmu- ne hepatitis. Aliment Pharmacol Ther 2003;17:1-16.
  • 13. Van Thiel DH, Wright H, Carroll P, Abu-Elmagd K, et al. Tacrolimus: a potential new treatment of autoimmune chronic active hepatitis results of an open label preliminary trial. Am J Gastroenterol 1995;90: 771-6.
  • 14. Fernandez NF, Redeker AG, Vierling JM, et al. Cyclosporine therapy in patients with steroid resistant autoimmune hepatitis. Am J Gastroenterol 1999;94: 241-8.
Year 2022, Volume: 2 Issue: 1, 24 - 27, 29.01.2022

Abstract

Supporting Institution

YOK

Project Number

YOK

Thanks

YOK

References

  • 1. Edward L. Krawitt, M.D., Autoimmune hepatitis. N.Engl. J. Med. 2006;354:54-66.
  • 2. Mc Farlane IG. Pathogenesis of autoimmune hepatitis. Biomed Pharmacother 1999;53(5-6): 255-63.
  • 3. Manns MP, Strassburg CP. Autoimmune hepatitis; Clinical challenges. Gastroenterelogy 2001;120: 1502-17.
  • 4. Ökten A, Demir S, Kaymakoğlu S, Çakaloğlu Y, Dinçer D, Beşışık F. Kronik hepatitlerin etiyolojik dağılımı. 14. Ulusal Gastroentereloji Kong. 28 Eylül-3 Ekim 1997, Merin. TJ Gastroenterol 1997, 8 (supll 1): A24.
  • 5. Alvarez F, Berg PA, Bianchi FB, et al. International Autoimmune Hepatitis Group report: review of criteria for diagnosis of autoimmune hepatitis. J Hepatol 1999;31:929-38.
  • 6. David H. Alpers, Autoimmune hepatitis, Gastroenterology Lippincott Williams Wilkins,2002, s.565.
  • 7. Teufel A, Gale PR, Kanzler S. Update on autoimmune hepatitis. World J Gastroenterol 2009;15:1035-41.
  • 8. Sherlock S, Dooley J. Chronic autoimmune hepatitis. In: Diseases of the Liver and Biliary System 10th edn. Oxford Blackwell : London, 1993: 308-15.
  • 9. Kaymakoğlu S. Otoimmun hepatit. Türkiye Klinikleri J Int Med Sci 2006;2:48-53.
  • 10. McFarlane IG. Autoimmune hepatitis; clinical manifestations and diagnostic criteria. Can J Gastroenterol 2001;15:107-13.
  • 11. Johnson PJ, McFarlane IG. Meeting report: International Autoimmune Hepatitis Group. Hepatology 1993;18:998-1005.
  • 12. Medina J, Garcia-Buey L, Moreno-Otero R. Review article: Immunopathogenetic and therapeutic aspects of autoimmu- ne hepatitis. Aliment Pharmacol Ther 2003;17:1-16.
  • 13. Van Thiel DH, Wright H, Carroll P, Abu-Elmagd K, et al. Tacrolimus: a potential new treatment of autoimmune chronic active hepatitis results of an open label preliminary trial. Am J Gastroenterol 1995;90: 771-6.
  • 14. Fernandez NF, Redeker AG, Vierling JM, et al. Cyclosporine therapy in patients with steroid resistant autoimmune hepatitis. Am J Gastroenterol 1999;94: 241-8.
There are 14 citations in total.

Details

Primary Language English
Subjects ​Internal Diseases
Journal Section Case Reports
Authors

Alihan Oral 0000-0003-1160-9340

Fatih Türker 0000-0002-8281-0319

Project Number YOK
Publication Date January 29, 2022
Submission Date December 31, 2021
Published in Issue Year 2022 Volume: 2 Issue: 1

Cite

EndNote Oral A, Türker F (January 1, 2022) A Case of Autoimmune Hepatitis Presenting with Fever and Bicytopenia. DAHUDER Medical Journal 2 1 24–27.



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