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<article  article-type="case-report"        dtd-version="1.4">
            <front>

                <journal-meta>
                                                                <journal-id>dev exp health med</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Developments and Experiments in Health and Medicine</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">3062-2948</issn>
                                                                                            <publisher>
                    <publisher-name>Dokuz Eylul University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.18614/dehm.1940003</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>​Internal Diseases</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>İç Hastalıkları</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Lymphedema and hypermobility: Posttraumatic lymphedema in an adolescent with hypermobility</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Soylu</surname>
                                    <given-names>Alper</given-names>
                                </name>
                                                                    <aff>DOKUZ EYLUL UNIVERSITY</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Yıldız</surname>
                                    <given-names>Gizem</given-names>
                                </name>
                                                                    <aff>DOKUZ EYLUL UNIVERSITY</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Karataş</surname>
                                    <given-names>Esra</given-names>
                                </name>
                                                                    <aff>DOKUZ EYLUL UNIVERSITY</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Yıldırım</surname>
                                    <given-names>Erkam</given-names>
                                </name>
                                                                    <aff>DOKUZ EYLUL UNIVERSITY</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Torun Bayram</surname>
                                    <given-names>Meral</given-names>
                                </name>
                                                                    <aff>DOKUZ EYLUL UNIVERSITY</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Kavukçu</surname>
                                    <given-names>Salih</given-names>
                                </name>
                                                                    <aff>DOKUZ EYLUL UNIVERSITY</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20260429">
                    <day>04</day>
                    <month>29</month>
                    <year>2026</year>
                </pub-date>
                                        <volume>40</volume>
                                        <issue>2</issue>
                                        <fpage>238</fpage>
                                        <lpage>243</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20250203">
                        <day>02</day>
                        <month>03</month>
                        <year>2025</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20251217">
                        <day>12</day>
                        <month>17</month>
                        <year>2025</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2025, Developments and Experiments in Health and Medicine</copyright-statement>
                    <copyright-year>2025</copyright-year>
                    <copyright-holder>Developments and Experiments in Health and Medicine</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Lymphedema arises primarily from abnormal lymphatic development or secondarily from injury to lymphatic tissues, with trauma being a common contributing factor. Although joint hypermobility can make individuals more susceptible to trauma-related complications, post-traumatic lymphedema has not previously been reported. Here, we describe an adolescent patient who developed post-traumatic lymphedema in association with joint hypermobility.</p></abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Hypermobility</kwd>
                                                    <kwd>  lymphedema</kwd>
                                                    <kwd>  trauma</kwd>
                                            </kwd-group>
                            
                                                                                                                        </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">1.	Warren AG, Brorson H, Borud LJ, Slavin SA. Lymphedema: a comprehensive review. Ann Plast Surg.2007;59:464-472. DOI:10.1097/01.sap.0000257149.42922.7e</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">2.	Liao CD, Kuruvilla AS, Krajewski A. A scoping literature review of post-traumatic lymphedema: Where are we now? J Plast Reconstr Aesthet Surg. 2022;75:2387-2440. DOI:10.1016/j.bjps.2022.02.059</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">3.	Hakim A, Grahame R. Joint hypermobility. Best Pract Res Clin Rheumatol. 2003; 17:989–1004.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">4.	Grahame R. Joint hypermobility and genetic collagen disorders: are they related? Arch Dis Child. 1999; 80:188–191.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">5.	Konopinski M, Graham I, Johnson MI, Jones G. The effect of hypermobility on the incidence of injury in professional football: A multi-site cohort study. Phys Ther Sport. 2016; 21:7-13. 
DOI: 10.1016/j.ptsp.2015.12.006.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">6.	Remvig L, Jensen DV, Ward RC. Are diagnostic criteria for general joint hypermobility and benign joint hypermobility syndrome based on reproducible and valid tests? A review of the literature. J Rheumatol. 2007;34:798-803.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">7.	Maclellan RA, Greene AK. Lymphedema. Semin Pediatr Surg. 2014;23:191–197.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">8.	Greene AK, Goss JA. Diagnosis and Staging of Lymphedema. Semin Plast Surg. 2018; 32:12–16.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">9.	Krapf JM, Goldstein AT. Two case presentations of profound labial edema as a presenting symptom of hypermobility-type Ehlers-Danlos syndrome. J Sex Med. 2013;10:2347-2350. DOI: 10.1111/jsm.12229.
10.	Dayan JH, Ly CL, Kataru RP, Mehrara BJ. Lymphedema: Pathogenesis and Novel Therapies. Annu Rev Med. 2018;69:263-276. DOI: 10.1146/annurev-med-060116-022900.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
