Dicle Medical Journal

1300-2945 1308-9889

Dicle University

10.5798/dicletip.1906501

Health Care Administration Medical Education Health Services and Systems (Other)

Sağlık Kurumları Yönetimi Tıp Eğitimi Sağlık Hizmetleri ve Sistemleri (Diğer)

Pregestasyonel Diabetus Mellitus Tanılı Gebe Hastaların Sistemik İnflamatuvar İndeks, Sistemik İnflamatuvar Yanıt İndeks, Toplam Sistemik İnflamatuvar İndekslerinin Değerlendirilmesi. Bir tersiyer merkez vaka -kontrol çalışması

Evaluation of Systemic Immune-Inflammation Index, Systemic Inflammation Response Index, and Aggregate Index of Systemic Inflammation in Pregestational Diabetes Mellitus Patients: A Tertiary Center Case-Control Study

Kayaalp

Hüseyin

BİLKENT ÜNİVERSİTESİ Tunç

Şeyhmus

gazi yaşargil eğitim araştırma hastanesi

03 10 2026

53 1 223 232 11 17 2025 02 02 2026

2003

Dicle Medical Journal

Amaç: Bu çalışmanın amacı Pregestasyonel diyabetes mellitus(Pre-GDM) tanılı hastaların Sistemik İnflamatuvar İndeks (Sİİ), Sistemik İnflamatuvar yanıt İndeks(SİRİ), toplam sistemik inflamatuvar indeks (AİSİ)’lerinin sağlıklı gebelerle karşılaştırılması, pre-GDM’li hastalarda Sİİ, SİRİ ve AİSİ sonuçlarının olumsuz sonuçları öngörmedeki rolünü incelemektir.Yöntemler: Bu çalışma tek merkezli, üçüncü basamak bir merkezde retrospektif olarak vaka kontrol olacak şekilde tasarlandı. Çalışmaya Şubat 2023 ile Şubat 2025 tarihleri arasında Pre-GDM tanılı 85 gebe hasta ve Pre-GDM tanılı olmayan 85 gebe hasta toplamda 170 gebe hasta dahil edildi. Çalışmaya dahil edilen hastalar pre-GDM tanısı olan çalışma grubu (grup1) ve pre-GDM tanısı olmayan kontrol grubu (grup 2) şeklinde 2 gruba ayrıldı. Çalışma ve kontrol grubu arasında maternal laboratuvar sonuçları, laboratuvar sonuçları sonrası oluşturulan Sİİ, SİRİ ve AİSİ sonuçları karşılaştırıldı. Ayrıca Pre-GDM tanılı hastalarda yenidoğan yoğun bakım (NICU)’a gidiş, birleşik olumsuz gebelik sonuçları (CAPO), preterm doğum (PTD)’ u öngörü etkinliği incelendi.Bulgular: Çalışma grubunda vücut kitle indeksi(VKİ)(p

Objective: This study aimed to compare the Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Aggregate Index of Systemic Inflammation (AISI) between pregnant women with Pregestational Diabetes Mellitus (Pre-GDM) and healthy controls, and to evaluate the predictive role of these indices for adverse pregnancy outcomes.Methods: This study was designed as a retrospective, case–control study conducted at a single tertiary care center. A total of 170 pregnant women who delivered between February 2023 and February 2025 were included: 85 with Pre-GDM and 85 without Pre-GDM. The participants were divided into two groups, with the study group consisting of patients diagnosed with pregestationaldiabetes mellitus (Group 1) and the control group including women without a pre-GDM diagnosis (Group 2). Maternal demographic and laboratory results, as well as inflammation indices (SII, SIRI, and AISI), were compared between the groups. In addition, the predictive performance of these indices for neonatal intensive care unit (NICU) admission, composite adverse pregnancy outcomes (CAPO), and preterm delivery (PTD) in patients with Pre-GDM was evaluated.Results: Body mass index (BMI) (p

Diabetes mellitus tip 2 nötrofil lenfosit trombosit yeni doğan yoğun bakım

Diabetes Mellitus Type 2 Neutrophil Lymphocyte Platelet Neonatal Intensive Care Unit.

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