Dicle Medical Journal 1300-2945 1308-9889 Dicle University 10.5798/diclemedj.0921.2015.02.0572 İnek sütü protein alerjisi Koca Tuğba Akçam Mustafa 07 09 2015 42 2 268 273 07 09 2015 Copyright © 2003, Dicle Medical Journal 2003 Dicle Medical Journal

Cow’s Milk Protein Allergy (CMPA) is the most common food allergy in early childhood. It affects between 2% and 3% of infants. Symptoms and signs related to CMPA which IgE-mediated or non IgE-mediated may involve many different organ systems. The first and most important step in diagnosis is a thorough medical history. Results of laboratory tests alone are not sufficient to make diagnosis, always need to be considered together with the clinical features. CMPA can occur with multiple immunological mechanisms, therefore the diagnosis chance increases with use of numerous tests together. However, the negative test does not exclude the diagnosis. The gold standards in diagnosis are food elimination and challenge tests. Cow’s milk and avoiding the use of its products, it is still considered as the first choice in the treatment of all children with CMPA

İnek Sütü Protein Alerjisi (İSPA) erken çocuklukta en sık görülen besin alerjisidir. Süt çocuklarının %2-3’ünde görülür. IgE aracılı veya IgE aracılı olmayan, birden fazla sistemi ilgilendiren klinik yakınmalar ile karşımıza çıkar. Genellikle erken çocukluk döneminde görülür ve geçicidir. Tanıda ilk ve en önemli basamak iyi alınmış bir öyküdür. Laboratuar testleri tek başına tanı koydurmaz, daima klinik ile birlikte değerlendirilmelidir. İSPA birden fazla immünolojik mekanizma ile oluşabildiğinden birden fazla testin bir arada kullanılması tanı şansını artırır. Ancak testlerin negatif olması tanıyı dışlamaz. Tanıda altın standart eliminasyon diyeti ve besin yükleme testidir. İnek sütü ve ürünlerinin kullanımından kaçınma, hala tüm çocuklarda İSPA tedavisinde ilk seçenek olarak kabul edilmektedir.Anahtar kelimeler: Eliminasyon diyeti, inek sütü protein alerjisi, tedavi, yükleme testi

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