Assessment of long term prognostic value of admission vitamin D level in patients with acute STEMI undergoing primary percutaneous coronary intervention

Year 2018, Volume: 45 Issue: 4, 369 - 377, 13.12.2018

Muhammet Hulusi Satilmisoglu Mehmet Gul , Huseyin Altug Cakmak Nilgun Isiksacan Selahattin Turen Ugur Kokturk Emre Yilmaz Muammer Karakayalı Aydin Rodi Tosu

https://doi.org/10.5798/dicletip.497879

Cited By: 1

Abstract

Objective:
Vitamin-D status is very important for optimal function of human body
especially cardiovascular system. The aim of this study was to investigate the
long term prognostic value of admission vitamin D level in acute ST-segment
elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary
intervention (PPCI).

Methods:
One hundred fifty seven consecutive patients, who were admitted to a training
and research hospital with a diagnosis of STEMI and underwent PPCI, were
recruited in this prospective study. The study patients were divided into 2
groups according to their vitamin-D levels as follows: High vitamin-D group
(n=80) and Low vitamin-D group (n=77). The severity of coronary artery disease
(CAD) was assessed with calculation of the SYNTAX score.

Results:
There were significant negative correlations between Vitamin-D level and SYNTAX
score, serum glucose, and gender, but a positive correlation with hemoglobin
level. Cardiovascular mortality was found to be significantly higher in the low
vitamin-D group as compared to the high group (p<0.001). In multivariate
analysis, low vitamin-D level was found as a significant independent predictor
of long term cardiovascular mortality after adjusting for other risk factors.

Conclusion:
We demonstrated that low admission vitamin-D is related to severity of CAD.
Vitamin-D deficiency is an independent predictor for long term cardiovascular
mortality in acute STEMI undergoing PPCI.

Keywords

Vitamin D; Mortality; SYNTAX score.

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