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The outcome of surgical treatment in patients with obstructive colorectal cancer

Year 2013, Volume: 40 Issue: 3, 401 - 405, 01.09.2013
https://doi.org/10.5798/diclemedj.0921.2013.03.0297

Abstract

Objectives: Colorectal cancer obstructions are responsible for about 85% of colonic emergencies. The aim of this study was to investigate the results of urgent surgical intervention that applied in acute colonic obstructions related to cancer. Methods: In this study, 86 cases presenting with acute colonic obstruction who were operated with the diagnosis of colonic tumor between January 2010 and December 2010 were assessed retrospectively. Age, gender, symptoms on presentation, presence of concomitant disease, surgical methods applied, complication and mortality rates were recorded. Results: Fifty of the cases were male, 36 were female. The mean age was 63.6 years. Twenty cases had undergone emergency colonoscopic examination at diagnosis and an obstructive lesion had been observed. The surgical operations performed were right hemicolectomy in 18, sigmoid resection in 34, left hemicolectomy in 10, abdomino-perineal resection in 2, subtotal colectomy in 4, transverse colectomy in two. Primary anastomosis was performed in thirty-four cases. Mortality was observed in 12 cases. Conclusions: In selected cases of left colon cancers with obstruction, resection and primary anastomosis is generally possible. Those over 70, presence of co-morbidities, albumin level under 3 g/dl, ASA score 3 and higher, blood loss of more than 500 ml, and preoperative blood transfusion were related to the high postoperative morbidity.

References

  • Coco C, Verbo A, Manno A, et al. Impact of emergency surgery in the outcome of rectal and left colon carcinoma. World J Surg 2005;29:1458-1464.
  • Zorcolo L, Covotta L, Carlomagno N, Bartolo DC. Safety of primary anastomosis in emergency colo-rectal surgery. Colorectal Dis 2003;5:262-269.
  • Alvarez JA, Baldonedo RF, Bear IG, et al. Presentation, treatment, and multivariate analysis of risk factors for ob- structive and perforative colorectal carcinoma. Am J Surg 2005;190:376-382.
  • Villar JM, Martinez AP, Villegas MT et al. Surgical options for malignant left-sided colonic obstruction. Surg Today 2005;35:275-281.
  • Jiang JK, Lan YT, Lin TC, et al. Primary vs. delayed resection for obstructive left-sided colorectal cancer: impact of sur- gery on patient outcome. Dis Colon Rectum 2008;51:306- 311.
  • Lee YM, Law WL, Chu KW, Poon RT. Emergency sur- gery for obstructing colorectal cancers: a comparison be- tween right-sided and leftsided lesions. J Am Coll Surg 2001;192:719-725.
  • Smothers L, Hynan L, Fleming J, et al. Emergency surgery for colon carcinoma. Dis Colon Rectum 2003;46:24-30.
  • Cuffy M, Abir F, Audisio RA, Longo WE. Colorectal cancer presenting as surgical emergencies. Surg Oncol 2004;13:149-157.
  • Phillips RK, Hittinger R, Fry JS, Fielding LP. Malignant Large bowel obstruction. Br J Surg 1985;72:296-302.
  • Irvin TT, Greaney MG. The treatment of colonic cancer pre- senting with intestinal obstruction. Br J Surg 1977;64:741- 744.
  • Serpell JW, McDermott FT, Katrivessis H, Hughes ES. Ob- structing carcinomas of the colon. Br J Surg 1989;76:965- 969.
  • Valerio D, Jones PF. Immediate resection in the treatment of large bowel emergencies. Br J Surg 1978;65:712-716.
  • Hsu TC. One-stage resection and anastomosis for acute ob- struction of the left colon. Dis Colon Rectum 1998;41:28- 32.
  • Ören D, Öztürk G. Kolorektal Kanserlerde Güncel Acil Tedavi. Türkiye Klinikleri J Gen Surg-Special Topics 2009;2:127-133.
  • Hsu TC. Comparison of one-stage resection and anastomo- sis of acute complete obstruction of left and right colon. Am J Surg 2005;189:384-387.
  • Bokey EL, Chapuis PH, Fung C, et al. Postoperative mor- bidity and mortality following resection of the colon and rectum for cancer. Dis Colon Rectum 1995;38:480-486.
  • Keymling M. Colorectal Stenting. Endoscopy 2003;35:234- 238.
  • Iversen LH, Bülow S, Christensen IJ, et al. Danish Colorec- tal Cancer Group. Postoperative medical complications are the main cause of early death after emergency surgery for colonic cancer. Br J Surg 2008;95:1012-1019.
  • Seah DW, Ibrahim S, Tay KH. Hartmann procedure: is it still relevant today? ANZ J Surg 2005;75:436-440.
  • Deen KI, Madoff RD, Goldberg SM, Rothenberger DA. Surgical management of left colon obstruction: the Uni- versity of Minnesota experience. J Am Coll Surg 1998; 187:573-576.
  • Sayek İ. Kolorektal karsinomlar. Sayek İ, ed. Temel Cerra- hi. Güneş kitabevi, Ankara 1996;1173-1177.
  • Onuk E, Tekin E. Kolon ve rektum kanserleri. Engin A, ed. Genel Cerrahi. Atlas kitapçılık, Ankara 2000;574-580.
  • Çayır K, Bilici M, Tekin SB, ve ark. Evre II-III kolon kan- serli hastalarda adjuvan tedavinin yan etki profilinin değer- lendirilmesi. Dicle Tıp Dergisi 2010;37:145-150.

Obstrüktif kolorektal kanserli hastalarda cerrahi tedavi sonuçları

Year 2013, Volume: 40 Issue: 3, 401 - 405, 01.09.2013
https://doi.org/10.5798/diclemedj.0921.2013.03.0297

Abstract

Amaç: Kolorektal kanserlere bağlı obstrüksiyonlar kolonik acillerin yaklaşık %85\'inden sorumludur. Bu çalışmanın amacı, kansere bağlı gelişen akut kolorektal obstrüksiyonlarda uygulanacak cerrahi girişimin sonuçlarını incelemektir. Yöntemler: Bu çalışmada Ocak 2000-Aralık 2010 tarihleri arasında kliniğimize akut kolon obstrüksiyonu ile başvuran ve kolon tümörü tanısı ile opere edilen 86 olgu retrospektif olarak değerlendirildi. Yaş, cins, başvuru anındaki semptomlar, ek hastalığının olup olmaması, uygulanan cerrahi yöntemler, komplikasyon ve mortalite oranları tespit edildi. Bulgular: Olguların 50\'si erkek, 36\'sı kadındı. Ortalama yaş 63,6 yıl idi. Olguların 20\'sinde tanıda acil kolonoskopik değerlendirme yapıldı ve tıkayıcı lezyon gözlendi. Olguların 18\'ine sağ hemikolektomi, 34\'üne sigmoid rezeksiyon, 10\'una sol hemikolektomi, 2\'sine abdomino-perineal rezeksiyon, 4\'üne subtotal kolektomi, 2\'sine transvers kolektomi yapıldı. Primer anastomoz 34 olguya yapıldı. Toplam 12 olguda mortalite görüldü. Sonuç: Obstrüktif sol kolon kanserlerinde seçilmiş vakalarda rezeksiyon ve primer anastomoz genellikle mümkündür. 70 üzeri yaş, komorbiditenin varlığı, albümin değerinin 3 g/dl\'nin altında olması, ASA skorunun 3 ve üzeri olması, 500 ml\'den fazla kan kaybı ve ameliyatta kan verilmesi postoperatif yüksek mortalite ile ilişkili bulundu.

References

  • Coco C, Verbo A, Manno A, et al. Impact of emergency surgery in the outcome of rectal and left colon carcinoma. World J Surg 2005;29:1458-1464.
  • Zorcolo L, Covotta L, Carlomagno N, Bartolo DC. Safety of primary anastomosis in emergency colo-rectal surgery. Colorectal Dis 2003;5:262-269.
  • Alvarez JA, Baldonedo RF, Bear IG, et al. Presentation, treatment, and multivariate analysis of risk factors for ob- structive and perforative colorectal carcinoma. Am J Surg 2005;190:376-382.
  • Villar JM, Martinez AP, Villegas MT et al. Surgical options for malignant left-sided colonic obstruction. Surg Today 2005;35:275-281.
  • Jiang JK, Lan YT, Lin TC, et al. Primary vs. delayed resection for obstructive left-sided colorectal cancer: impact of sur- gery on patient outcome. Dis Colon Rectum 2008;51:306- 311.
  • Lee YM, Law WL, Chu KW, Poon RT. Emergency sur- gery for obstructing colorectal cancers: a comparison be- tween right-sided and leftsided lesions. J Am Coll Surg 2001;192:719-725.
  • Smothers L, Hynan L, Fleming J, et al. Emergency surgery for colon carcinoma. Dis Colon Rectum 2003;46:24-30.
  • Cuffy M, Abir F, Audisio RA, Longo WE. Colorectal cancer presenting as surgical emergencies. Surg Oncol 2004;13:149-157.
  • Phillips RK, Hittinger R, Fry JS, Fielding LP. Malignant Large bowel obstruction. Br J Surg 1985;72:296-302.
  • Irvin TT, Greaney MG. The treatment of colonic cancer pre- senting with intestinal obstruction. Br J Surg 1977;64:741- 744.
  • Serpell JW, McDermott FT, Katrivessis H, Hughes ES. Ob- structing carcinomas of the colon. Br J Surg 1989;76:965- 969.
  • Valerio D, Jones PF. Immediate resection in the treatment of large bowel emergencies. Br J Surg 1978;65:712-716.
  • Hsu TC. One-stage resection and anastomosis for acute ob- struction of the left colon. Dis Colon Rectum 1998;41:28- 32.
  • Ören D, Öztürk G. Kolorektal Kanserlerde Güncel Acil Tedavi. Türkiye Klinikleri J Gen Surg-Special Topics 2009;2:127-133.
  • Hsu TC. Comparison of one-stage resection and anastomo- sis of acute complete obstruction of left and right colon. Am J Surg 2005;189:384-387.
  • Bokey EL, Chapuis PH, Fung C, et al. Postoperative mor- bidity and mortality following resection of the colon and rectum for cancer. Dis Colon Rectum 1995;38:480-486.
  • Keymling M. Colorectal Stenting. Endoscopy 2003;35:234- 238.
  • Iversen LH, Bülow S, Christensen IJ, et al. Danish Colorec- tal Cancer Group. Postoperative medical complications are the main cause of early death after emergency surgery for colonic cancer. Br J Surg 2008;95:1012-1019.
  • Seah DW, Ibrahim S, Tay KH. Hartmann procedure: is it still relevant today? ANZ J Surg 2005;75:436-440.
  • Deen KI, Madoff RD, Goldberg SM, Rothenberger DA. Surgical management of left colon obstruction: the Uni- versity of Minnesota experience. J Am Coll Surg 1998; 187:573-576.
  • Sayek İ. Kolorektal karsinomlar. Sayek İ, ed. Temel Cerra- hi. Güneş kitabevi, Ankara 1996;1173-1177.
  • Onuk E, Tekin E. Kolon ve rektum kanserleri. Engin A, ed. Genel Cerrahi. Atlas kitapçılık, Ankara 2000;574-580.
  • Çayır K, Bilici M, Tekin SB, ve ark. Evre II-III kolon kan- serli hastalarda adjuvan tedavinin yan etki profilinin değer- lendirilmesi. Dicle Tıp Dergisi 2010;37:145-150.
There are 23 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Abdullah Kısaoğlu This is me

Bünyami Özoğul This is me

Ayhan Aköz This is me

Sabri Selçuk Atamanalp This is me

Gürkan Öztürk This is me

Mehmet İlhan Yıldırgan This is me

Publication Date September 1, 2013
Submission Date March 2, 2015
Published in Issue Year 2013 Volume: 40 Issue: 3

Cite

APA Kısaoğlu, A., Özoğul, B., Aköz, A., Atamanalp, S. S., et al. (2013). Obstrüktif kolorektal kanserli hastalarda cerrahi tedavi sonuçları. Dicle Medical Journal, 40(3), 401-405. https://doi.org/10.5798/diclemedj.0921.2013.03.0297
AMA Kısaoğlu A, Özoğul B, Aköz A, Atamanalp SS, Öztürk G, Yıldırgan Mİ. Obstrüktif kolorektal kanserli hastalarda cerrahi tedavi sonuçları. diclemedj. September 2013;40(3):401-405. doi:10.5798/diclemedj.0921.2013.03.0297
Chicago Kısaoğlu, Abdullah, Bünyami Özoğul, Ayhan Aköz, Sabri Selçuk Atamanalp, Gürkan Öztürk, and Mehmet İlhan Yıldırgan. “Obstrüktif Kolorektal Kanserli Hastalarda Cerrahi Tedavi sonuçları”. Dicle Medical Journal 40, no. 3 (September 2013): 401-5. https://doi.org/10.5798/diclemedj.0921.2013.03.0297.
EndNote Kısaoğlu A, Özoğul B, Aköz A, Atamanalp SS, Öztürk G, Yıldırgan Mİ (September 1, 2013) Obstrüktif kolorektal kanserli hastalarda cerrahi tedavi sonuçları. Dicle Medical Journal 40 3 401–405.
IEEE A. Kısaoğlu, B. Özoğul, A. Aköz, S. S. Atamanalp, G. Öztürk, and M. İ. Yıldırgan, “Obstrüktif kolorektal kanserli hastalarda cerrahi tedavi sonuçları”, diclemedj, vol. 40, no. 3, pp. 401–405, 2013, doi: 10.5798/diclemedj.0921.2013.03.0297.
ISNAD Kısaoğlu, Abdullah et al. “Obstrüktif Kolorektal Kanserli Hastalarda Cerrahi Tedavi sonuçları”. Dicle Medical Journal 40/3 (September 2013), 401-405. https://doi.org/10.5798/diclemedj.0921.2013.03.0297.
JAMA Kısaoğlu A, Özoğul B, Aköz A, Atamanalp SS, Öztürk G, Yıldırgan Mİ. Obstrüktif kolorektal kanserli hastalarda cerrahi tedavi sonuçları. diclemedj. 2013;40:401–405.
MLA Kısaoğlu, Abdullah et al. “Obstrüktif Kolorektal Kanserli Hastalarda Cerrahi Tedavi sonuçları”. Dicle Medical Journal, vol. 40, no. 3, 2013, pp. 401-5, doi:10.5798/diclemedj.0921.2013.03.0297.
Vancouver Kısaoğlu A, Özoğul B, Aköz A, Atamanalp SS, Öztürk G, Yıldırgan Mİ. Obstrüktif kolorektal kanserli hastalarda cerrahi tedavi sonuçları. diclemedj. 2013;40(3):401-5.