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The relationship between the risk of the gestational diabetes mellitus with respect to maternal age and initial body mass index

Year 2013, Volume: 40 Issue: 3, 406 - 409, 01.09.2013
https://doi.org/10.5798/diclemedj.0921.2013.03.0298

Abstract

Objective: To establish the risk of the gestational diabetes mellitus (GDM) with respect to maternal age and body mass index (BMI). Methods: The data of the patients, admitted to our clinic for pregnancy follow up between 2007 and 2011were collected retrospectively. 50 gram and 100 gram screening test results, birth weight of the newborns and demographic features of the patients were recorded. Results: 544 patients were included. Mean age of the patients was 30.2±4.2 years, mean BMI value was 23.3±4.1 kg/m2 (15.6-66), mean gestational age at delivery was 38.9±1.2 weeks (34.9-42), and mean birth weight was 3409±415 grams. The odds ratio for GDM at the patients above 40 years old was 7.84 and the odds ratio for patients with a body mass index ≥25 was 1.74. Conclusion: Gestational diabetes mellitus increases with advanced maternal age and body mass index. The patients with a body mass index ≥25 at the antenatal visits may be offered regular nutrition and exercise program and get pregnant after having a body mass index below 25 if possible.

References

  • Toraman AR, Gürel A, Ulusal Z, et al. Evaluation of glucose challenge and oral glucose tolerance test results in preg- nancy and estimination of prevalence of gestational diabe- tes mellitus at Sema Hospital in İstanbul. Turk J Med Sci 2012;42:1235-1240.
  • Classification and diagnosis of diabetes and other categories of glucose intolerance. National Diabetes Data Group. Dia- betes 1979;28:1039-1057.
  • American Diabetes Association, ‘Diagnosis and classifica- tion of diabetes mellitus’. Diabetes Care 2011;34:62-69.
  • Yogev Y, Visser GH. Obesity, gestational diabetes and preg- nancy outcome. Semin Fetal Neonatal Med 2009;14:77-84.
  • Hillier TA, Pedula KL, Schmidt MM, et al. Childhood obe- sity and metabolic imprinting: the ongoing effects of ma- ternal hyperglycemia. Diabetes Care 2007;30:2287-2292.
  • Crowther CA, Hiller JE, Moss JR, et al. Australian Carbohy- drate Intolerance Study in Pregnant Women (ACHOIS) Tri- al Group. Effect of treatment of gestational diabetes mel- litus on pregnancy outcomes. N Eng J Med 2005;352:2477- 2486.
  • ACOG Practice Bulletin: Clinical management guidelines for obstetrician-gynecologists. Gestational Diabetes. Obs- tet Gynecol 2001;98:525-538.
  • Teede HJ, Harrison CL, Teh WT, et al. Gestational Diabetes: development of an early risk prediction tool to facilitate oppurtunities for prevention, Aust NZ J Obstet Gynecol 2011;51:499-504.
  • Morisset AS, St-Yves A, Veillette J, et al. Prevention of gesta- tional diabetes mellitus: a review of studies on weight man- agement. Diabetes Metab Res Rev 2010;26:17-25.
  • Engelgau MM, Herman WH, Smith PJ, et al. The epidemi- ology of diabetes and pregnancy in the U.S., 1988. Diabetes Care 1995;18:1029-1033.
  • Kitzmiller JL. Cost analysis of diagnosis and treatment of gestational diabetes mellitus. Clin Obstet Gynecol 2000;43:140-153.
  • Sweeney AT, Brown FM. Gestational diabetes mellitus. Clin Lab Med 2001;21:173-192.
  • Makgoba M, Savvidou MD, Steer PJ. An analysis of the relationship between maternal age, body mass index and ra- cial origin in the development of gestational diabetes mel- litus. BJOG 2012;119:276-282.
  • Carpenter MW, Coustan DR. Criteria for screening tests for gestational diabetes. Am J Obstet Gynecol 1982;144:768-773.
  • Turgut A, Boran SÜ, Dolgun ZN, et al. Bir doğumevi gebe izlem polikliniğinde gestasyonel diyabetes mellitus sıklığı. Dicle Med J 2011;38:325-328.
  • Erem C, Cihanyurdu N, Deger O, et al. Screening for ges- tational diabetes mellitus in northeastern Turkey (Trabzon City). Eur J Epidemiol 2003;18.39-43.
  • Caliskan E, Kayikcioglu F, Oztürk N, et al. A population- based risk factor scoring will decrease unnecessary testing for the diagnosis of gestational diabetes mellitus. Acta Ob- stet Gynecol Scand 2004;83:524-530.
  • Tanir HM, Sener T, Gürer H, Kaya M. A ten-year gesta- tional diabetes mellitus cohort at a university clinic of the mid-Anatolian region of Turkey. Clin Exp Obstet Gynecol 2005;32:241-244.
  • Karcaaltincaba D, Kandemir O, Yalvac S, et al. Prevalence of gestational diabetes mellitus and gestational impaired glucose tolerance in pregnant women by National Diabetes Data Group and Carpenter and Coustan criteria. Int J Gyn- aecol Obstet 2009;106:246-249.
  • Karcaaltincaba D, Buyukkaragoz B, Kandemir O, et al. Gestational diabetes and gestational impaired glucose tol- erance in 1653 teenage pregnancies: prevalence, risk fac- tors and pregnancy outcomes. J Pediatr Adolesc Gynecol 2011;24:62-65.
  • Stuebe AM, Landon MB, Lai Y, et al. Maternal BMI, glu- cose tolerance, and adverse pregnancy outcomes. Am J Ob- stet Gynecol 2012;20:62-67.
  • Ricart W, Lopez J, Mozas J, et al. Spanish group for the Study of the Impact of Carpenter and Coustan GDM Thresholds. Body mass index has a greater impact on preg- nancy outcomes than gestational hyperglycaemia. Diabeto- logia 2005; 48:1736-1742.
  • Ryan EA. Diagnosing gestational diabetes. Diabetologia 2011;54:480-486.
  • Wollf S, Legarth J, Vangsgaard K, et al. A randomized trial of the effects of dietary counseling on gestational weight gain and glucose metabolism in obese pregnant women. Int J Obes 2008;32:495-501.
  • Landon MB; Spong CY, Thom E, et al. A multicenter, ran- domized trial of treatment for mild gestational diabetes. N Engl J Med 2009;361:1339-1348.
  • Kanagalingam MG, Forouhi NG, Greer IA, Sattar N. Changes in booking body mass index over a decade: ret- rospective analysis from a Glasgow Maternity Hospital. BJOG 2005;112:1431-1433.
  • Tobias DK, Zhang C, van Dam RM, et al. Physical activity before and during pregnancy and risk of gestational diabetes mellitus : a metaanalysis. Diabetes Care 2011;34:223-229.
  • Corrado F, D’Anna R, Cannata ML, et al. Positive associa- tion between a single abnormal glucose tolerance test value and subsequent abnormal glucose tolerance. Am J Obstet Gynecol 2007;196:1-5.
  • Malinowska-Polubiec A, Sienko J, Lewandowski Z, et al. Risk factors of abnormal carbohydrate metabolism after pregnancy complicated by gestational diabetes mellitus. Gynecol Endocrinol 2012;28:360-364.
  • TNSA-2008-Nüfus Etütleri-Hacettepe Üniversitesi www. hips.hacettepe.edu.tr/tnsa2008/analiz.shtml.

Gestasyonel diabetes mellitus riskinin maternal yaş ve gebeliğin başlangıcındaki vücut kitle indeksi ile ilişkisi

Year 2013, Volume: 40 Issue: 3, 406 - 409, 01.09.2013
https://doi.org/10.5798/diclemedj.0921.2013.03.0298

Abstract

Amaç: Anne yaşı ve vücut kitle indeksine (VKİ) göre Gestasyonel Diabetes Mellitus (GDM) riskini belirlemek Yöntemler: 2007-2011 yılları arasında hastanemizde takip edilmiş gebelerin kartları retrospektif olarak taranıp, 50 gram ve 100 gram tarama testlerinin sonuçları, bebeklerin doğum kiloları ve demografik verileri kaydedildi. Bulgular: 544 hasta çalışmaya dâhil edildi. Hastaların ortalama yaşı 30,2±4,2 yıl, ortalama VKİ değeri 23,3±4,1 kg/m2 (15,6-66), ortalama doğum haftası 38,9±1,2 hafta (34,9-42), ortalama doğum ağırlığı 3409±415 gram olarak bulundu. 40 yaş üzeri olgularda GDM için odds oranı 7.84, VKİ≥25 olanlar için odds oranı 1,74 olarak hesaplandı. Sonuç: Gestasyonel DM sıklığı ileri anne yaşı ve artan VKİ ile artmaktadır. Gebelik öncesi takiplerinde VKİ≥25 olan hastalara beslenme ve egzersiz önerilmeli, mümkünse VKİ

References

  • Toraman AR, Gürel A, Ulusal Z, et al. Evaluation of glucose challenge and oral glucose tolerance test results in preg- nancy and estimination of prevalence of gestational diabe- tes mellitus at Sema Hospital in İstanbul. Turk J Med Sci 2012;42:1235-1240.
  • Classification and diagnosis of diabetes and other categories of glucose intolerance. National Diabetes Data Group. Dia- betes 1979;28:1039-1057.
  • American Diabetes Association, ‘Diagnosis and classifica- tion of diabetes mellitus’. Diabetes Care 2011;34:62-69.
  • Yogev Y, Visser GH. Obesity, gestational diabetes and preg- nancy outcome. Semin Fetal Neonatal Med 2009;14:77-84.
  • Hillier TA, Pedula KL, Schmidt MM, et al. Childhood obe- sity and metabolic imprinting: the ongoing effects of ma- ternal hyperglycemia. Diabetes Care 2007;30:2287-2292.
  • Crowther CA, Hiller JE, Moss JR, et al. Australian Carbohy- drate Intolerance Study in Pregnant Women (ACHOIS) Tri- al Group. Effect of treatment of gestational diabetes mel- litus on pregnancy outcomes. N Eng J Med 2005;352:2477- 2486.
  • ACOG Practice Bulletin: Clinical management guidelines for obstetrician-gynecologists. Gestational Diabetes. Obs- tet Gynecol 2001;98:525-538.
  • Teede HJ, Harrison CL, Teh WT, et al. Gestational Diabetes: development of an early risk prediction tool to facilitate oppurtunities for prevention, Aust NZ J Obstet Gynecol 2011;51:499-504.
  • Morisset AS, St-Yves A, Veillette J, et al. Prevention of gesta- tional diabetes mellitus: a review of studies on weight man- agement. Diabetes Metab Res Rev 2010;26:17-25.
  • Engelgau MM, Herman WH, Smith PJ, et al. The epidemi- ology of diabetes and pregnancy in the U.S., 1988. Diabetes Care 1995;18:1029-1033.
  • Kitzmiller JL. Cost analysis of diagnosis and treatment of gestational diabetes mellitus. Clin Obstet Gynecol 2000;43:140-153.
  • Sweeney AT, Brown FM. Gestational diabetes mellitus. Clin Lab Med 2001;21:173-192.
  • Makgoba M, Savvidou MD, Steer PJ. An analysis of the relationship between maternal age, body mass index and ra- cial origin in the development of gestational diabetes mel- litus. BJOG 2012;119:276-282.
  • Carpenter MW, Coustan DR. Criteria for screening tests for gestational diabetes. Am J Obstet Gynecol 1982;144:768-773.
  • Turgut A, Boran SÜ, Dolgun ZN, et al. Bir doğumevi gebe izlem polikliniğinde gestasyonel diyabetes mellitus sıklığı. Dicle Med J 2011;38:325-328.
  • Erem C, Cihanyurdu N, Deger O, et al. Screening for ges- tational diabetes mellitus in northeastern Turkey (Trabzon City). Eur J Epidemiol 2003;18.39-43.
  • Caliskan E, Kayikcioglu F, Oztürk N, et al. A population- based risk factor scoring will decrease unnecessary testing for the diagnosis of gestational diabetes mellitus. Acta Ob- stet Gynecol Scand 2004;83:524-530.
  • Tanir HM, Sener T, Gürer H, Kaya M. A ten-year gesta- tional diabetes mellitus cohort at a university clinic of the mid-Anatolian region of Turkey. Clin Exp Obstet Gynecol 2005;32:241-244.
  • Karcaaltincaba D, Kandemir O, Yalvac S, et al. Prevalence of gestational diabetes mellitus and gestational impaired glucose tolerance in pregnant women by National Diabetes Data Group and Carpenter and Coustan criteria. Int J Gyn- aecol Obstet 2009;106:246-249.
  • Karcaaltincaba D, Buyukkaragoz B, Kandemir O, et al. Gestational diabetes and gestational impaired glucose tol- erance in 1653 teenage pregnancies: prevalence, risk fac- tors and pregnancy outcomes. J Pediatr Adolesc Gynecol 2011;24:62-65.
  • Stuebe AM, Landon MB, Lai Y, et al. Maternal BMI, glu- cose tolerance, and adverse pregnancy outcomes. Am J Ob- stet Gynecol 2012;20:62-67.
  • Ricart W, Lopez J, Mozas J, et al. Spanish group for the Study of the Impact of Carpenter and Coustan GDM Thresholds. Body mass index has a greater impact on preg- nancy outcomes than gestational hyperglycaemia. Diabeto- logia 2005; 48:1736-1742.
  • Ryan EA. Diagnosing gestational diabetes. Diabetologia 2011;54:480-486.
  • Wollf S, Legarth J, Vangsgaard K, et al. A randomized trial of the effects of dietary counseling on gestational weight gain and glucose metabolism in obese pregnant women. Int J Obes 2008;32:495-501.
  • Landon MB; Spong CY, Thom E, et al. A multicenter, ran- domized trial of treatment for mild gestational diabetes. N Engl J Med 2009;361:1339-1348.
  • Kanagalingam MG, Forouhi NG, Greer IA, Sattar N. Changes in booking body mass index over a decade: ret- rospective analysis from a Glasgow Maternity Hospital. BJOG 2005;112:1431-1433.
  • Tobias DK, Zhang C, van Dam RM, et al. Physical activity before and during pregnancy and risk of gestational diabetes mellitus : a metaanalysis. Diabetes Care 2011;34:223-229.
  • Corrado F, D’Anna R, Cannata ML, et al. Positive associa- tion between a single abnormal glucose tolerance test value and subsequent abnormal glucose tolerance. Am J Obstet Gynecol 2007;196:1-5.
  • Malinowska-Polubiec A, Sienko J, Lewandowski Z, et al. Risk factors of abnormal carbohydrate metabolism after pregnancy complicated by gestational diabetes mellitus. Gynecol Endocrinol 2012;28:360-364.
  • TNSA-2008-Nüfus Etütleri-Hacettepe Üniversitesi www. hips.hacettepe.edu.tr/tnsa2008/analiz.shtml.
There are 30 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Nilgün Güdücü This is me

Gökçenur Gönenç This is me

Herman İşçi This is me

Alin Başgül Yiğiter This is me

İlkkan Dünder This is me

Publication Date September 1, 2013
Submission Date March 2, 2015
Published in Issue Year 2013 Volume: 40 Issue: 3

Cite

APA Güdücü, N., Gönenç, G., İşçi, H., Yiğiter, A. B., et al. (2013). Gestasyonel diabetes mellitus riskinin maternal yaş ve gebeliğin başlangıcındaki vücut kitle indeksi ile ilişkisi. Dicle Medical Journal, 40(3), 406-409. https://doi.org/10.5798/diclemedj.0921.2013.03.0298
AMA Güdücü N, Gönenç G, İşçi H, Yiğiter AB, Dünder İ. Gestasyonel diabetes mellitus riskinin maternal yaş ve gebeliğin başlangıcındaki vücut kitle indeksi ile ilişkisi. diclemedj. September 2013;40(3):406-409. doi:10.5798/diclemedj.0921.2013.03.0298
Chicago Güdücü, Nilgün, Gökçenur Gönenç, Herman İşçi, Alin Başgül Yiğiter, and İlkkan Dünder. “Gestasyonel Diabetes Mellitus Riskinin Maternal Yaş Ve gebeliğin başlangıcındaki vücut Kitle Indeksi Ile ilişkisi”. Dicle Medical Journal 40, no. 3 (September 2013): 406-9. https://doi.org/10.5798/diclemedj.0921.2013.03.0298.
EndNote Güdücü N, Gönenç G, İşçi H, Yiğiter AB, Dünder İ (September 1, 2013) Gestasyonel diabetes mellitus riskinin maternal yaş ve gebeliğin başlangıcındaki vücut kitle indeksi ile ilişkisi. Dicle Medical Journal 40 3 406–409.
IEEE N. Güdücü, G. Gönenç, H. İşçi, A. B. Yiğiter, and İ. Dünder, “Gestasyonel diabetes mellitus riskinin maternal yaş ve gebeliğin başlangıcındaki vücut kitle indeksi ile ilişkisi”, diclemedj, vol. 40, no. 3, pp. 406–409, 2013, doi: 10.5798/diclemedj.0921.2013.03.0298.
ISNAD Güdücü, Nilgün et al. “Gestasyonel Diabetes Mellitus Riskinin Maternal Yaş Ve gebeliğin başlangıcındaki vücut Kitle Indeksi Ile ilişkisi”. Dicle Medical Journal 40/3 (September 2013), 406-409. https://doi.org/10.5798/diclemedj.0921.2013.03.0298.
JAMA Güdücü N, Gönenç G, İşçi H, Yiğiter AB, Dünder İ. Gestasyonel diabetes mellitus riskinin maternal yaş ve gebeliğin başlangıcındaki vücut kitle indeksi ile ilişkisi. diclemedj. 2013;40:406–409.
MLA Güdücü, Nilgün et al. “Gestasyonel Diabetes Mellitus Riskinin Maternal Yaş Ve gebeliğin başlangıcındaki vücut Kitle Indeksi Ile ilişkisi”. Dicle Medical Journal, vol. 40, no. 3, 2013, pp. 406-9, doi:10.5798/diclemedj.0921.2013.03.0298.
Vancouver Güdücü N, Gönenç G, İşçi H, Yiğiter AB, Dünder İ. Gestasyonel diabetes mellitus riskinin maternal yaş ve gebeliğin başlangıcındaki vücut kitle indeksi ile ilişkisi. diclemedj. 2013;40(3):406-9.