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EFFECTS OF FISH OIL ON CARDIOVASCULAR DISEASES

Year 2005, Issue: 008, 179 - 198, 15.07.2005

Abstract

The aim of the present study is to review the crucial findings concerning the effects of fish oil on coronary heart diseases. This research area was very important for public health and has been under intensive investigation in recent years. The benifical effects of fish oil lire mainly due to the effects of eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) which are n-3 (also known as 00-3) fatty acids. These important fatty acids are mainly found in fishes. In this review, the health effects of fish oil are limited to their effects on triglycerid. lipoprotein, blood viscosity, atherosclerosis, thrombosis, bleeding time, blood pressure, arrhythmias, myocardial infarction as well as sudden cardiac death.

References

  • [1] Agren, J., Muje, P., Hanninen, 0., Herranen, 1., PenttIla, I., 1987. "Seasonal Variations of Lipid Fatty Acids of Boreal Freshwater Fish Species" Compo Biochem. Physio!., 88,905-909.
  • [2] Ahlgren, G., 1996. "Fatty Acid Content of Some Freshwater Fish In Lakes cf Different Trophic Levels" Eco!. Freshwater Fish, 5 (1), 15-27.
  • [3] Albert, CM, Campos, H., Stampfer, MJ., Ridker, P.M., Manson, 1.E., Willett, W.e., Ma, 1., 2002. "Blood Levels of Long-Chain n-3 Fatty Acids and the Risk of Sudden Death" N Engl J Med., 346(15), 1113-1118.
  • [4] Andrade, A.P., 1995. "Omega3 Fatty Acids in Freshwater Fish From South Brazil" Jour. of the American Oil Chemists, 72 (10), 1207-1210.
  • [5] Carlson, S.E., Salem, N., 1990. "Essentiality of Omega3 Fatty Acids in Growth and Development of Infants" World Review of Nutrition and Dietetics, 66, 74-86.
  • [6] Cobiac, L., Clifton, P.M., Abbey, M., Belling, G.B., 1991. "Nestel, PJ., Lipid, lipoprotein, and hemostatic effects of fish vs fish-oil n-fatty acids in mildly hyperlipidemic males" Am J Clin Nutr., 53(5): 1210-1216.
  • [7] Daviglus, M.L., Stamler, 1., Greenland, P., Dyer, A.R., Liu, K., 1997. "Fish consumption and risk of coronary heart disease. What does the evidence show?" Eur Heart 1., 18(12), 1841-1842.
  • [8] Durrington, P.N., Bhatnagar, D., Mackness, M.I., Morgan, 1., Julier, K., Khan, M.A., France, M., 2001. "An omega-3 polyunsaturated fatty acid concentrate administered for one year decreased triglycerides in simvastatin treated patients with coronary heart disease and persisting hypertriglyceridaernia" Heart, 85(5), 544-548.
  • [9] Eritsland, 1., 2000. "Safety considerations of polyunsaturated fatty acids" Am J Clin Nutr., 71(1), 197-201.
  • [10] Galli, c, Butrum, R. 1990. "Dietary Omega3 Fatty Acids and Cancer" World Review of Nutrition and Dietetics., 66,446-461.
  • [11] Gama, R., Elfatih, AB., Anderson, N.R., 2002. "Ethnic differences in total and HDL cholesterol concentrations: Caucasians compared with predominantly Punjabi Sikh Indo- Asians" Ann Clin Biochem., 39(6):609-11.
  • [12] He, K., Rimm, E.B., Merchant, A, Rosner, B.A, Stampfer, M.J., Willett, W.c., Ascherio, A, 2002. "Fish consumption and risk of stroke in men" The Journal of the American Medical Association, 288(24), 3130-3136
  • [13] Hu, F.B., Cho, E., Rexrode, K.M., Albert, C.M., Manson, lE., 2003. "Fish and long-chain omega-3 fatty acid intake and risk of coronary heart disease and total mortality in diabetic women" Circulation, 107(141 1852-1857
  • [14] Hu, F.B., Bronner, L., Willett, W.c., Stampfer, M.J., Rexrode, K.M., Albert, C.M., Hunter, D., Manson, lE., 2002. "Fish and omega-3 fatty acid intake and risk of coronary heart disease in women" JAMA, 287(14):1815-1821.
  • [15] Jouven, X., Charles, M.A, Desnos, M., Ducimetiere, P., 2001. "Circulating nonesterified fatty acid level as a predictive risk factor for sudden death inthe population" Circulation, 104 (7), 756-761.
  • [16] Kanders, B., Kowalchuk, M., 1990. "Omega3 Fatty Acids and Cancer Metostasis in Humans" World Review of Nutrition and Dietetics, 66, 477-487.
  • [17] Laidlaw, M., Holub, B.J., 2003. "Effects of supplementation with fish oil-derived n-3 fatty acids and gamma-linolenic acid on circulating plasma lipids and fatty acid profiles in women" Am J Clin Nutr., 77(1), 37-42.
  • [18] Leaf, A, Weber, P.c., 1988. "Cardiovascular Effects of n-3 Fatty Acids" Journal of Medicine, 318, 549-557.
  • [19] Leaf, A, 2001. "Diet and sudden cardiac death" J Nutr Health Aging. 5(3), 173-178.
  • [20] Leaf, A., Kang, J.X., 200l. "Omega-3 fatty acids and cardiovascular disease" World Rev Nutr Diet., 89, 161-172.
  • [21] Li, x., Steiner, M., 1990. "Fish Oil, a Potent Inhibitor of Flatelet Adhesiveness" World Review of Nutrition and Dietetics, 66, 562- 563.
  • [22] Marchioli, R, Schweiger, c., Tavazzi, L., Valagussa, F, 2001. "Efficacy of n-3 polyunsaturated fatty acids after myocardial infarction" Lipids, (36), 119-126.
  • [23] Marchioli, R, Barzi, F, Bomba, E., Chieffo, c., Di Gregorio, D., Di Mascio, R, Franzosi, M.G., Geraci, E., Levantesi, G., Maggioni, A.P., Mantini, L., Marfisi, RM., Mastrogiuseppe, G., Mininni, N., Nicolosi, G.L., Santini, M., Schweiger, c., Tavazzi, L., Tognoni, G., Tucci, c., Valagussa, F, 2002. "Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per 10 Studio della Sopravvivenza nell'Infarto Miocardico" Circulation, 105(16), 1897-1903.
  • [24] Namara, D.J., 1992. "Dietary Fatty Acid, Lipoproteins and Cardiovascular Disease" Advantures in Food and Nutrition Research, 36, 254-334.
  • [25] Nestel, P., Shige, H., Pomeroy, S., Cehun, M., Abbey, M., Raederstorff, D., 2002. "The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans" Am J Clin Nutr., 76(2), 326-330.
  • [26] Nikkila, M., 1991. "Influence of fish oil on blood lipids in coronary artery disease" Eur J Clin Nutr., 45(4):209-213.
  • [27] Nordoy, A., Marchioli, R., Arnesen, H., Videbaek, J., 2001. "n-3 polyunsaturated fatty acids and cardiovascular diseases" Lipids, 36,127-129.
  • [28] Penny, M., William, S. H., Lawrence, lA., 2002. "Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease" Circulation. 106:2747-2757.
  • [29] Pepping, J., 1999. "Omega-3 essential fatty acids" Am J Health Syst Pharm., 56(8), 719-720.
  • [30] Rambjor, G.S., Walen, A.I. , Windsor, S.L., Harris, W.S., 1996. "Eicosapentaenoic acid is imarily responsible for hypotriglyceridemic effect of fish oil in humans" Lipids, 45-49
  • [31] Saglik, S., 1994. Bazi Bahk, Midye ve Karides Turlerinin Yag Asidi Kompozisyonlan ve Kolesterol lccriklcrinin Gaz Kromatografik incelenmesi. istanbul Univ. Saghk Bil. Enst. Analitik Kimya A.B.D., Doktora Tezi, 60s, istanbul.
  • [32] Salachas, A., Papadopoulos, C, Sakadamis, G., Styliadis, 1., Voudris, V., Oakley, D., Saynor, R., 1994. "Effects of a low-dose fish oil concentrate on angina, exercise tolerance time, serum triglycerides, and platelet function" Angiology, 45(12), 1023-1031.
  • [33] Saynor, R., Gillott, T., 1992. "Changes in blood lipids and fibrinogen with a note on safety in a long term study on the effects of n-3 fatty acids in subjects receiving fish oil supplements and followed for seven years"Lipids, 27(7), 533-538.
  • [34] Skerrett, PJ., Hennekens,C.H., 2003. "Consumption of fish and fish oils and decreased risk of stroke" Prev Cardiol., 6(1):38-41.
  • [35] Simopoulos, A.P., 2002. ''The importance of the ratio of omega- 6/omega-3 essential fatty acids" Biomed Pharmacother, 56(8):365- 379.
  • [36] Simopoulos, A.P.,1997. "Omega-3 fatty acids in the preventionmanagement of cardiovascular disease" Can J Physiol Pharmacol. 75(3), 234-239.
  • [37] Simopoulos, A.P., 1991. "Omega-3 fatty acids in healty and dease and in growth and development " American Journal Clinical Nutrician, 54: 438-463
  • [38] Simon, 1.A. , Hodgkins, M.L., Browner, W.S., Neuhaus, J.M., Bernert, 1.T., Hulley, S.B., 1995. "Serum fatty acids and the risk of coronary heart disease" Am J Epidemiol., 142(5),469-476.
  • [39] Sinclair, AJ., O'dea, KO., 1990. "History of Fat in The Human Diet" World Review of Nutrition and Dietetics, 66,511-512.
  • [40] Sirtori, ex. Galli, e., 2002. "N-3 fatty acids and diabetes" iomed Pharmacother, (8):397-406.
  • [41] Theobald, H.E., Chowienczyk, PJ., Whittall, R., Humphries, S.E., Sanders, T.A., 20(;-1-.LDL cholesterol-raising effect of low-dose docosahexaenoic acid in middle-aged men and women Am J Clin Nutr., 79(4):558-63.
  • [42] Thies, F, Garry, J.M., Yaqoob, P., Rerkasem, K, Williams, J., Shearman, c.r., Gallagher, PJ., Calder, P.e., Grimble, R.F., 2003. "Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial" Lancet, 361 (9356):4 77-485.
  • [43] Toft, 1., Bonaa, KH., Ingebretsen, O.e., Nordoy, A, Jenssen, T., 1995. "Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial" Ann Intern Med., 23(12), 911-918.
  • [44] Uysal, K, 2000. Egirdir Galli Sudak ( Stizostedion lucioperca Lin., 1758) Bahklannm Total Lipit, Total Yag Asidi ve Yag Asidi Bilesiminin Mevsimsel incelenmesi. Fen Bil. Enst. Su Urunleri Temel Bilirnleri AB.D., Doktora Tezi, 66s. Egirdir - Isparta.
  • [45] Vanhoutte, P.M., Shimokawa, H., 1990. "Fish Oil and The Platelet- Blood Vessel Wall Interaction" World Review of Nutrition and Dietetics, 66, 233-244.
  • [46] Weber, P., Leaf, A., 1990. "Cardiovascular Effects of n-3 Fatty Acids" World Review of Nutrition and Dietetics, 66, 218- 232.
  • [47] Weber, P., Raederstorff, D., 2000. "Triglyceride-lowering effect of omega-3 LC-polyunsaturated fatty acids" Nutr Metab Cardiovasc Dis. 10(1):28-37.
  • [48] Ziboh, V.A, 1990. "CD3 Polyunsaturated Constituents of Fish oil and the Management Fatty Acid of Skin Inflammatory and Scaly and Dietetics, 66, 425-435.

BALIK YAGININ KORONER KALP HASTALIKLARI UZERiNE ETKisi

Year 2005, Issue: 008, 179 - 198, 15.07.2005

Abstract

Bu cahsmamn arnaci; bahk yagmm koroner kalp hastaliklan uzerine etkilerinin c;:all~Ildlgl arasurmalan incelemek ve onernli olan bulgulan derlemektir. Konu, ozellikle halk saghgl acismdan cok onernlidir ve son yillarda en fazla arasunlan konular arasindadrr. Bahk yagmm saghkla ilgili faydah etkileri n-3 (w-3 olarak da bilinir) formunda olan okosapentaenoik (EPA) ve dokosaheksaenoik (DHA) asitlerden kaynaklanmaktadir. Bu onernli yag asitleri baliga ozgudur. Makalede; balik yagirun butun ozellikleri ve insan saghgl iizerindeki butun etkileri degil, sadece trigliserid, lipoprotein, kan vizkozitesi, damar sertligi, kan pihnlasrnasi, kanama zamaru, damar tikamkhgr, kalp ritim bozukluklan, kalp krizi ve ani olumler iizerine etkileri incelenmistir,

References

  • [1] Agren, J., Muje, P., Hanninen, 0., Herranen, 1., PenttIla, I., 1987. "Seasonal Variations of Lipid Fatty Acids of Boreal Freshwater Fish Species" Compo Biochem. Physio!., 88,905-909.
  • [2] Ahlgren, G., 1996. "Fatty Acid Content of Some Freshwater Fish In Lakes cf Different Trophic Levels" Eco!. Freshwater Fish, 5 (1), 15-27.
  • [3] Albert, CM, Campos, H., Stampfer, MJ., Ridker, P.M., Manson, 1.E., Willett, W.e., Ma, 1., 2002. "Blood Levels of Long-Chain n-3 Fatty Acids and the Risk of Sudden Death" N Engl J Med., 346(15), 1113-1118.
  • [4] Andrade, A.P., 1995. "Omega3 Fatty Acids in Freshwater Fish From South Brazil" Jour. of the American Oil Chemists, 72 (10), 1207-1210.
  • [5] Carlson, S.E., Salem, N., 1990. "Essentiality of Omega3 Fatty Acids in Growth and Development of Infants" World Review of Nutrition and Dietetics, 66, 74-86.
  • [6] Cobiac, L., Clifton, P.M., Abbey, M., Belling, G.B., 1991. "Nestel, PJ., Lipid, lipoprotein, and hemostatic effects of fish vs fish-oil n-fatty acids in mildly hyperlipidemic males" Am J Clin Nutr., 53(5): 1210-1216.
  • [7] Daviglus, M.L., Stamler, 1., Greenland, P., Dyer, A.R., Liu, K., 1997. "Fish consumption and risk of coronary heart disease. What does the evidence show?" Eur Heart 1., 18(12), 1841-1842.
  • [8] Durrington, P.N., Bhatnagar, D., Mackness, M.I., Morgan, 1., Julier, K., Khan, M.A., France, M., 2001. "An omega-3 polyunsaturated fatty acid concentrate administered for one year decreased triglycerides in simvastatin treated patients with coronary heart disease and persisting hypertriglyceridaernia" Heart, 85(5), 544-548.
  • [9] Eritsland, 1., 2000. "Safety considerations of polyunsaturated fatty acids" Am J Clin Nutr., 71(1), 197-201.
  • [10] Galli, c, Butrum, R. 1990. "Dietary Omega3 Fatty Acids and Cancer" World Review of Nutrition and Dietetics., 66,446-461.
  • [11] Gama, R., Elfatih, AB., Anderson, N.R., 2002. "Ethnic differences in total and HDL cholesterol concentrations: Caucasians compared with predominantly Punjabi Sikh Indo- Asians" Ann Clin Biochem., 39(6):609-11.
  • [12] He, K., Rimm, E.B., Merchant, A, Rosner, B.A, Stampfer, M.J., Willett, W.c., Ascherio, A, 2002. "Fish consumption and risk of stroke in men" The Journal of the American Medical Association, 288(24), 3130-3136
  • [13] Hu, F.B., Cho, E., Rexrode, K.M., Albert, C.M., Manson, lE., 2003. "Fish and long-chain omega-3 fatty acid intake and risk of coronary heart disease and total mortality in diabetic women" Circulation, 107(141 1852-1857
  • [14] Hu, F.B., Bronner, L., Willett, W.c., Stampfer, M.J., Rexrode, K.M., Albert, C.M., Hunter, D., Manson, lE., 2002. "Fish and omega-3 fatty acid intake and risk of coronary heart disease in women" JAMA, 287(14):1815-1821.
  • [15] Jouven, X., Charles, M.A, Desnos, M., Ducimetiere, P., 2001. "Circulating nonesterified fatty acid level as a predictive risk factor for sudden death inthe population" Circulation, 104 (7), 756-761.
  • [16] Kanders, B., Kowalchuk, M., 1990. "Omega3 Fatty Acids and Cancer Metostasis in Humans" World Review of Nutrition and Dietetics, 66, 477-487.
  • [17] Laidlaw, M., Holub, B.J., 2003. "Effects of supplementation with fish oil-derived n-3 fatty acids and gamma-linolenic acid on circulating plasma lipids and fatty acid profiles in women" Am J Clin Nutr., 77(1), 37-42.
  • [18] Leaf, A, Weber, P.c., 1988. "Cardiovascular Effects of n-3 Fatty Acids" Journal of Medicine, 318, 549-557.
  • [19] Leaf, A, 2001. "Diet and sudden cardiac death" J Nutr Health Aging. 5(3), 173-178.
  • [20] Leaf, A., Kang, J.X., 200l. "Omega-3 fatty acids and cardiovascular disease" World Rev Nutr Diet., 89, 161-172.
  • [21] Li, x., Steiner, M., 1990. "Fish Oil, a Potent Inhibitor of Flatelet Adhesiveness" World Review of Nutrition and Dietetics, 66, 562- 563.
  • [22] Marchioli, R, Schweiger, c., Tavazzi, L., Valagussa, F, 2001. "Efficacy of n-3 polyunsaturated fatty acids after myocardial infarction" Lipids, (36), 119-126.
  • [23] Marchioli, R, Barzi, F, Bomba, E., Chieffo, c., Di Gregorio, D., Di Mascio, R, Franzosi, M.G., Geraci, E., Levantesi, G., Maggioni, A.P., Mantini, L., Marfisi, RM., Mastrogiuseppe, G., Mininni, N., Nicolosi, G.L., Santini, M., Schweiger, c., Tavazzi, L., Tognoni, G., Tucci, c., Valagussa, F, 2002. "Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per 10 Studio della Sopravvivenza nell'Infarto Miocardico" Circulation, 105(16), 1897-1903.
  • [24] Namara, D.J., 1992. "Dietary Fatty Acid, Lipoproteins and Cardiovascular Disease" Advantures in Food and Nutrition Research, 36, 254-334.
  • [25] Nestel, P., Shige, H., Pomeroy, S., Cehun, M., Abbey, M., Raederstorff, D., 2002. "The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans" Am J Clin Nutr., 76(2), 326-330.
  • [26] Nikkila, M., 1991. "Influence of fish oil on blood lipids in coronary artery disease" Eur J Clin Nutr., 45(4):209-213.
  • [27] Nordoy, A., Marchioli, R., Arnesen, H., Videbaek, J., 2001. "n-3 polyunsaturated fatty acids and cardiovascular diseases" Lipids, 36,127-129.
  • [28] Penny, M., William, S. H., Lawrence, lA., 2002. "Fish Consumption, Fish Oil, Omega-3 Fatty Acids, and Cardiovascular Disease" Circulation. 106:2747-2757.
  • [29] Pepping, J., 1999. "Omega-3 essential fatty acids" Am J Health Syst Pharm., 56(8), 719-720.
  • [30] Rambjor, G.S., Walen, A.I. , Windsor, S.L., Harris, W.S., 1996. "Eicosapentaenoic acid is imarily responsible for hypotriglyceridemic effect of fish oil in humans" Lipids, 45-49
  • [31] Saglik, S., 1994. Bazi Bahk, Midye ve Karides Turlerinin Yag Asidi Kompozisyonlan ve Kolesterol lccriklcrinin Gaz Kromatografik incelenmesi. istanbul Univ. Saghk Bil. Enst. Analitik Kimya A.B.D., Doktora Tezi, 60s, istanbul.
  • [32] Salachas, A., Papadopoulos, C, Sakadamis, G., Styliadis, 1., Voudris, V., Oakley, D., Saynor, R., 1994. "Effects of a low-dose fish oil concentrate on angina, exercise tolerance time, serum triglycerides, and platelet function" Angiology, 45(12), 1023-1031.
  • [33] Saynor, R., Gillott, T., 1992. "Changes in blood lipids and fibrinogen with a note on safety in a long term study on the effects of n-3 fatty acids in subjects receiving fish oil supplements and followed for seven years"Lipids, 27(7), 533-538.
  • [34] Skerrett, PJ., Hennekens,C.H., 2003. "Consumption of fish and fish oils and decreased risk of stroke" Prev Cardiol., 6(1):38-41.
  • [35] Simopoulos, A.P., 2002. ''The importance of the ratio of omega- 6/omega-3 essential fatty acids" Biomed Pharmacother, 56(8):365- 379.
  • [36] Simopoulos, A.P.,1997. "Omega-3 fatty acids in the preventionmanagement of cardiovascular disease" Can J Physiol Pharmacol. 75(3), 234-239.
  • [37] Simopoulos, A.P., 1991. "Omega-3 fatty acids in healty and dease and in growth and development " American Journal Clinical Nutrician, 54: 438-463
  • [38] Simon, 1.A. , Hodgkins, M.L., Browner, W.S., Neuhaus, J.M., Bernert, 1.T., Hulley, S.B., 1995. "Serum fatty acids and the risk of coronary heart disease" Am J Epidemiol., 142(5),469-476.
  • [39] Sinclair, AJ., O'dea, KO., 1990. "History of Fat in The Human Diet" World Review of Nutrition and Dietetics, 66,511-512.
  • [40] Sirtori, ex. Galli, e., 2002. "N-3 fatty acids and diabetes" iomed Pharmacother, (8):397-406.
  • [41] Theobald, H.E., Chowienczyk, PJ., Whittall, R., Humphries, S.E., Sanders, T.A., 20(;-1-.LDL cholesterol-raising effect of low-dose docosahexaenoic acid in middle-aged men and women Am J Clin Nutr., 79(4):558-63.
  • [42] Thies, F, Garry, J.M., Yaqoob, P., Rerkasem, K, Williams, J., Shearman, c.r., Gallagher, PJ., Calder, P.e., Grimble, R.F., 2003. "Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial" Lancet, 361 (9356):4 77-485.
  • [43] Toft, 1., Bonaa, KH., Ingebretsen, O.e., Nordoy, A, Jenssen, T., 1995. "Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial" Ann Intern Med., 23(12), 911-918.
  • [44] Uysal, K, 2000. Egirdir Galli Sudak ( Stizostedion lucioperca Lin., 1758) Bahklannm Total Lipit, Total Yag Asidi ve Yag Asidi Bilesiminin Mevsimsel incelenmesi. Fen Bil. Enst. Su Urunleri Temel Bilirnleri AB.D., Doktora Tezi, 66s. Egirdir - Isparta.
  • [45] Vanhoutte, P.M., Shimokawa, H., 1990. "Fish Oil and The Platelet- Blood Vessel Wall Interaction" World Review of Nutrition and Dietetics, 66, 233-244.
  • [46] Weber, P., Leaf, A., 1990. "Cardiovascular Effects of n-3 Fatty Acids" World Review of Nutrition and Dietetics, 66, 218- 232.
  • [47] Weber, P., Raederstorff, D., 2000. "Triglyceride-lowering effect of omega-3 LC-polyunsaturated fatty acids" Nutr Metab Cardiovasc Dis. 10(1):28-37.
  • [48] Ziboh, V.A, 1990. "CD3 Polyunsaturated Constituents of Fish oil and the Management Fatty Acid of Skin Inflammatory and Scaly and Dietetics, 66, 425-435.
There are 48 citations in total.

Details

Primary Language Turkish
Subjects Structural Biology
Journal Section Articles
Authors

K. Uysal This is me

M. Yöntem This is me

M. Dönmez This is me

Publication Date July 15, 2005
Published in Issue Year 2005 Issue: 008

Cite

APA Uysal, K., Yöntem, M., & Dönmez, M. (2005). BALIK YAGININ KORONER KALP HASTALIKLARI UZERiNE ETKisi. Journal of Science and Technology of Dumlupınar University(008), 179-198.

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