Year 2020, Volume 22 , Issue 1, Pages 1 - 6 2020-04-30

Comparison of Hemogram Parameters in Febrile Seizures Types
Febril Nöbet Tiplerinde Hemogram Parametrelerinin Karşılaştırılması

Zühal ÖRNEK [1] , Hakan KARDEŞ [2] , İbrahim Etem PİŞKİN [3] , Mustafa ÇALIK [4]


Aim: Febrile seizures (FS) are among the most common neurological emergencies during childhood and clinically classified into two types, being simple febrile seizures (SFS) and complicated febrile seizures (CFS). The differentiation between FS types is important, in that they are associated with different morbidity and mortality risks and it is based on the clinical characteristics of each seizure, however there is currently no laboratory test that can guide this differentiation. In this study, the relationship between FS types and hemogram parameters was evaluated and potential use of these parameters in differential diagnosis was investigated.
Material and Methods: This retrospective study included a total of 133 patients whose first FS met the criteria of an FS, and whose hemogram results were available. The American Academy of Pediatrics criteria were used to confirm the diagnosis. The patients were divided into two groups as SFS and CFS.
Results: Hemoglobin (Hb), hematocrit (HCT), mean platelet volume (MPV), neutrophil lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) differed significantly between two groups (p<0.001, p=0.002, p=0.033, p<0.001, p<0.001, respectively), while no significant difference was identified in total blood count parameters. Moreover, MPV was significantly higher in CFS group than in SFS group.
Conclusion: This is one of the few studies investigating the potential relationship between hemogram parameters and FS types in children. We believe that, although they do not ensure a clear differentiation, Hb, MPV, NLR and PLR may be useful to clinicians in differentiating between FS types, particularly in patients with an unclear seizure history
Amaç: Febril nöbetler (FN) çocukluk çağında en sık görülen nörolojik aciller arasındadır ve klinik olarak basit febril nöbetler (BFN) ve komplike febril nöbetler (KFN) olmak üzere iki tipte sınıflandırılır. FN tiplerinin ayrımı, farklı morbidite ve mortalite riskleriyle ilişkili olması ve her nöbetin klinik özelliklerine dayanması nedeniyle önemlidir, ancak şu anda bu farklılaşmaya yol gösterecek laboratuvar testi bulunmamaktadır. Bu çalışmada FN tipleri ve hemogram parametreleri arasındaki ilişki incelenmiş ve bu parametrelerin ayırıcı tanıda potansiyel kullanımı araştırılmıştır.
Gereç ve Yöntemler: Bu retrospektif çalışmaya, FN kriterlerine uyan, ilk defa FN geçiren ve hemogram sonuçlarına ulaşılabilen toplam 133 hasta dahil edildi. Tanıyı doğrulamak için Amerikan Pediatri Akademisi kriterleri kullanıldı. Hastalar BFN ve KFN olmak üzere iki gruba ayrıldı.
Bulgular: Her iki grup arasında hemoglobin (Hb), hematokrit (HCT), ortalama trombosit hacmi (MPV), nötrofil lenfosit oranı (NLO) ve trombosit lenfosit oranı (TLO) değerleri anlamlı şekilde farklıyken (sırasıyla p<0,001; p=0,002; p=0,033; p<0,001; p<0,001) diğer tam kan sayımı parametrelerinde ise anlamlı bir farklılık yoktu. Ayrıca, KFN grubunda MPV, BFN grubuna göre anlamlı derecede yüksekti.
Sonuç: Bu çalışma çocuklarda hemogram parametreleri ile FN tipleri arasındaki potansiyel ilişkiyi araştıran az sayıdaki çalışmadan biridir. Hemoglobin, MPV, NLO ve TLO’nun kesin bir ayrım sağlamasa da özellikle nöbet hikayesi net olmayan hastalarda klinisyenlere FN tiplerinin ayırt edilmesinde yardımcı olacağını düşünmekteyiz
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Primary Language en
Subjects Medicine
Journal Section Research Article
Authors

Orcid: 0000-0001-9252-1652
Author: Zühal ÖRNEK (Primary Author)
Institution: BÜLENT ECEVİT ÜNİVERSİTESİ, TIP FAKÜLTESİ
Country: Turkey


Orcid: 0000-0002-0553-7072
Author: Hakan KARDEŞ
Institution: BÜLENT ECEVİT ÜNİVERSİTESİ, TIP FAKÜLTESİ

Orcid: 0000-0002-1651-6639
Author: İbrahim Etem PİŞKİN
Institution: BÜLENT ECEVİT ÜNİVERSİTESİ, TIP FAKÜLTESİ

Orcid: 0000-0002-6389-3355
Author: Mustafa ÇALIK
Institution: HARRAN ÜNİVERSİTESİ, TIP FAKÜLTESİ

Dates

Publication Date : April 30, 2020

Bibtex @research article { dtfd628239, journal = {Duzce Medical Journal}, issn = {}, eissn = {1307-671X}, address = {}, publisher = {Duzce University}, year = {2020}, volume = {22}, pages = {1 - 6}, doi = {10.18678/dtfd.628239}, title = {Comparison of Hemogram Parameters in Febrile Seizures Types}, key = {cite}, author = {Örnek, Zühal and Kardeş, Hakan and Pişkin, İbrahim Etem and Çalık, Mustafa} }
APA Örnek, Z , Kardeş, H , Pişkin, İ , Çalık, M . (2020). Comparison of Hemogram Parameters in Febrile Seizures Types . Duzce Medical Journal , 22 (1) , 1-6 . DOI: 10.18678/dtfd.628239
MLA Örnek, Z , Kardeş, H , Pişkin, İ , Çalık, M . "Comparison of Hemogram Parameters in Febrile Seizures Types" . Duzce Medical Journal 22 (2020 ): 1-6 <https://dergipark.org.tr/en/pub/dtfd/issue/53917/628239>
Chicago Örnek, Z , Kardeş, H , Pişkin, İ , Çalık, M . "Comparison of Hemogram Parameters in Febrile Seizures Types". Duzce Medical Journal 22 (2020 ): 1-6
RIS TY - JOUR T1 - Comparison of Hemogram Parameters in Febrile Seizures Types AU - Zühal Örnek , Hakan Kardeş , İbrahim Etem Pişkin , Mustafa Çalık Y1 - 2020 PY - 2020 N1 - doi: 10.18678/dtfd.628239 DO - 10.18678/dtfd.628239 T2 - Duzce Medical Journal JF - Journal JO - JOR SP - 1 EP - 6 VL - 22 IS - 1 SN - -1307-671X M3 - doi: 10.18678/dtfd.628239 UR - https://doi.org/10.18678/dtfd.628239 Y2 - 2020 ER -
EndNote %0 Düzce Tıp Fakültesi Dergisi Comparison of Hemogram Parameters in Febrile Seizures Types %A Zühal Örnek , Hakan Kardeş , İbrahim Etem Pişkin , Mustafa Çalık %T Comparison of Hemogram Parameters in Febrile Seizures Types %D 2020 %J Duzce Medical Journal %P -1307-671X %V 22 %N 1 %R doi: 10.18678/dtfd.628239 %U 10.18678/dtfd.628239
ISNAD Örnek, Zühal , Kardeş, Hakan , Pişkin, İbrahim Etem , Çalık, Mustafa . "Comparison of Hemogram Parameters in Febrile Seizures Types". Duzce Medical Journal 22 / 1 (April 2020): 1-6 . https://doi.org/10.18678/dtfd.628239
AMA Örnek Z , Kardeş H , Pişkin İ , Çalık M . Comparison of Hemogram Parameters in Febrile Seizures Types. Duzce Medical Journal. 2020; 22(1): 1-6.
Vancouver Örnek Z , Kardeş H , Pişkin İ , Çalık M . Comparison of Hemogram Parameters in Febrile Seizures Types. Duzce Medical Journal. 2020; 22(1): 1-6.
IEEE Z. Örnek , H. Kardeş , İ. Pişkin and M. Çalık , "Comparison of Hemogram Parameters in Febrile Seizures Types", Duzce Medical Journal, vol. 22, no. 1, pp. 1-6, Apr. 2020, doi:10.18678/dtfd.628239