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Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens

Year 2024, , 1461 - 1478, 31.07.2024

Gökçe Gürün , Funda Karbancıoğlu Güler

https://doi.org/10.29130/dubited.1365178

Abstract

Changes in agricultural practices, individual diversity, the considerable size of the global food trade, immigrant and tourist circulation, with microorganism transformations have led to the formation of microorganisms that are resistant to chemicals and implementations used, especially antibiotics. Antimicrobial photodynamic therapy (aPDT) is an approach based on the interaction of a natural/synthetic photosensitizer, a suitable light source, and molecular oxygen, and the cytotoxic effect of reactive oxygen species resulting from this interaction on the target microorganism. The benefits of this method, which has found its place in medical terms by treating oral biofilms, superficial lesions, and chronic sinusitis, are limited by problems of low cell/tissue penetration, poor selectivity, non-thermal effect, and off-target damage. Despite similar practical problems in food science, developing technology is expected to encourage new studies on pathogen inactivation in food matrices, reducing the microbial load to safe levels, extending shelf life, and preventing quality loss.

Keywords

Photodynamic Therapy Photosensitizers Free Radicals Foodborne Pathogens

References

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Antimikrobiyal Fotodinamik Terapi: Gıda Kaynaklı Patojenler için Yeni Konsept

Year 2024, , 1461 - 1478, 31.07.2024

Gökçe Gürün , Funda Karbancıoğlu Güler

https://doi.org/10.29130/dubited.1365178

Abstract

Tarımsal uygulamalardaki değişiklikler, bireysel çeşitlilik, küresel gıda ticaretinin hatırı sayılır büyüklüğü, göçmen ve turist dolaşımı, mikroorganizma dönüşümleri ile başta antibiyotikler olmak üzere kimyasallara ve kullanılan uygulamalara karşı dirençli mikroorganizmaların oluşmasına yol açmıştır. Antimikrobiyal fotodinamik tedavi (aPDT), doğal/sentetik bir ışığa duyarlılaştırıcı, uygun bir ışık kaynağı ve moleküler oksijenin etkileşimi ile bu etkileşim sonucu ortaya çıkan reaktif oksijen türlerinin hedef mikroorganizma üzerinde sitotoksik etkisine dayanan bir yaklaşımdır. Oral biyofilmleri, yüzeysel lezyonları ve kronik sinüziti tedavi ederek tıbbi anlamda kendine yer bulan bu yöntemin faydaları, düşük hücre/doku penetrasyonu, zayıf seçicilik, termal olmayan etki ve hedef dışı hasar sorunları nedeniyle sınırlıdır. Gıda bilimindeki benzer uygulamaya yönelik sorunlara rağmen gelişen teknolojinin, gıda matrislerinde patojen inaktivasyonu, mikrobiyal yükün güvenli seviyelere indirilmesi, raf ömrünün uzatılması ve kalite kaybının önlenmesi konularında yeni çalışmaları teşvik etmesi beklenmektedir.

Keywords

Fotodinamik tedavi Işığa duyarlılaştırıcılar Serbest radikaller Gıda patojenleri

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There are 65 citations in total.

Details

Primary Language English
Subjects Agricultural Engineering (Other)
Journal Section Articles
Authors

Gökçe Gürün 0000-0003-4737-597X

Funda Karbancıoğlu Güler 0000-0001-6576-0084

Publication Date July 31, 2024
Published in Issue Year 2024

Cite

APA Gürün, G., & Karbancıoğlu Güler, F. (2024). Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens. Duzce University Journal of Science and Technology, 12(3), 1461-1478. https://doi.org/10.29130/dubited.1365178
AMA Gürün G, Karbancıoğlu Güler F. Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens. DÜBİTED. July 2024;12(3):1461-1478. doi:10.29130/dubited.1365178
Chicago Gürün, Gökçe, and Funda Karbancıoğlu Güler. “Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens”. Duzce University Journal of Science and Technology 12, no. 3 (July 2024): 1461-78. https://doi.org/10.29130/dubited.1365178.
EndNote Gürün G, Karbancıoğlu Güler F (July 1, 2024) Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens. Duzce University Journal of Science and Technology 12 3 1461–1478.
IEEE G. Gürün and F. Karbancıoğlu Güler, “Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens”, DÜBİTED, vol. 12, no. 3, pp. 1461–1478, 2024, doi: 10.29130/dubited.1365178.
ISNAD Gürün, Gökçe - Karbancıoğlu Güler, Funda. “Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens”. Duzce University Journal of Science and Technology 12/3 (July 2024), 1461-1478. https://doi.org/10.29130/dubited.1365178.
JAMA Gürün G, Karbancıoğlu Güler F. Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens. DÜBİTED. 2024;12:1461–1478.
MLA Gürün, Gökçe and Funda Karbancıoğlu Güler. “Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens”. Duzce University Journal of Science and Technology, vol. 12, no. 3, 2024, pp. 1461-78, doi:10.29130/dubited.1365178.
Vancouver Gürün G, Karbancıoğlu Güler F. Antimicrobial Photodynamic Therapy: Novel Concept for Foodborne Pathogens. DÜBİTED. 2024;12(3):1461-78.