Research Article
Year 2018,
Volume: 4 Issue: 2, 1 - 5, 01.11.2018
Abstract
In this study, the effect of pesticides on the enzyme
activity of Aldose reductase (AR) (EC 1.1.1.21), which is involved in polyol
pathway and detoxification reactions, has been investigated.For this purpose,
AR enzyme was purified from chicken liver and the IC50 values were
plotted as % Activity-[I] for pesticides with inhibition effect and The maximum
inhibitory effect was determined at 2,4,5-T with 162μM.
Keywords
References
- 1. Straathof, A. J.; Panke, S.; Schmid, A., The production of fine chemicals by biotransformations. Current opinion in biotechnology 2002, 13, (6), 548-556.2. Pollard, D. J.; Woodley, J. M., Biocatalysis for pharmaceutical intermediates: the future is now. TRENDS in Biotechnology 2007, 25, (2), 66-73.3. Şengül, B.; Beydemir, Ş., The interactions of cephalosporins on polyol pathway enzymes from sheep kidney. Archives of physiology and biochemistry 2018, 124, (1), 35-44.
Year 2018,
Volume: 4 Issue: 2, 1 - 5, 01.11.2018
Abstract
References
- 1. Straathof, A. J.; Panke, S.; Schmid, A., The production of fine chemicals by biotransformations. Current opinion in biotechnology 2002, 13, (6), 548-556.2. Pollard, D. J.; Woodley, J. M., Biocatalysis for pharmaceutical intermediates: the future is now. TRENDS in Biotechnology 2007, 25, (2), 66-73.3. Şengül, B.; Beydemir, Ş., The interactions of cephalosporins on polyol pathway enzymes from sheep kidney. Archives of physiology and biochemistry 2018, 124, (1), 35-44.
There are 1 citations in total.
Details
| Primary Language | English |
|---|---|
| Journal Section | makaleler |
| Authors | |
| Publication Date | November 1, 2018 |
| Published in Issue | Year 2018 Volume: 4 Issue: 2 |