<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.4 20241031//EN"
        "https://jats.nlm.nih.gov/publishing/1.4/JATS-journalpublishing1-4.dtd">
<article  article-type="research-article"        dtd-version="1.4">
            <front>

                <journal-meta>
                                                                <journal-id>el-cezeri journal of science and engineering</journal-id>
            <journal-title-group>
                                                                                    <journal-title>El-Cezeri</journal-title>
            </journal-title-group>
                            <issn pub-type="ppub">2148-3736</issn>
                                        <issn pub-type="epub">2148-3736</issn>
                                                                                            <publisher>
                    <publisher-name>Tayfun UYGUNOĞLU</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.31202/ecjse.1169424</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Engineering</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Mühendislik</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <trans-title-group xml:lang="en">
                                    <trans-title>Segmentation of Brain Tumor MRI Images with U-Net Architecture</trans-title>
                                </trans-title-group>
                                                                                                                                                                                                <article-title>U-Net Mimarisi ile Beyin Tümörü MRI Görüntülerinin Segmentasyonu</article-title>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-8246-6733</contrib-id>
                                                                <name>
                                    <surname>Uzun</surname>
                                    <given-names>Süleyman</given-names>
                                </name>
                                                                    <aff>SAKARYA UNIVERSITY OF APPLIED SCIENCES, FACULTY OF TECHNOLOGY, DEPARTMENT OF COMPUTER ENGINEERING, COMPUTER ENGINEERING PR.</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-0098-9018</contrib-id>
                                                                <name>
                                    <surname>Güney</surname>
                                    <given-names>Emin</given-names>
                                </name>
                                                                    <aff>SAKARYA UYGULAMALI BİLİMLER ÜNİVERSİTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0001-7003-8416</contrib-id>
                                                                <name>
                                    <surname>Bingöl</surname>
                                    <given-names>Bünyamin</given-names>
                                </name>
                                                                    <aff>SAKARYA UYGULAMALI BİLİMLER ÜNİVERSİTESİ, TEKNOLOJİ FAKÜLTESİ, ELEKTRİK-ELEKTRONİK MÜHENDİSLİĞİ BÖLÜMÜ, ELEKTRİK-ELEKTRONİK MÜHENDİSLİĞİ PR.</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20221231">
                    <day>12</day>
                    <month>31</month>
                    <year>2022</year>
                </pub-date>
                                        <volume>9</volume>
                                        <issue>4</issue>
                                        <fpage>1583</fpage>
                                        <lpage>1590</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20220901">
                        <day>09</day>
                        <month>01</month>
                        <year>2022</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20221229">
                        <day>12</day>
                        <month>29</month>
                        <year>2022</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2013, El-Cezeri</copyright-statement>
                    <copyright-year>2013</copyright-year>
                    <copyright-holder>El-Cezeri</copyright-holder>
                </permissions>
            
                                                                                                <trans-abstract xml:lang="en">
                            <p>With the development of deep learning methods in recent years, image processing has gained importance in health. One of the most common studies in this field is the rapid and accurate diagnosis of cancerous brain tumors. Brain tumors are one of the leading causes of death in cancer patients, especially in children and the elderly. Especially in the last ten years, the development of GPU computing technologies and the increase in studies in deep learning also contributed to this field. In this study, a system that detects brain tumor cells by using U-Net architecture with 512x512 filter sizes on MRI images has been implemented. In the study, the BRATS dataset, one of the global datasets frequently used in the literature, was used. As a result of the survey, a dice score of 91.38% was obtained, which can be accepted as reliable.</p></trans-abstract>
                                                                                                                                    <abstract><p>Son yıllarda derin öğrenme yöntemlerinin gelişmesiyle birlikte, sağlık alanında görüntü işleme konusu oldukça önem kazanmıştır. Bu alanda yapılan en yaygın çalışmalardan birisi de kanserli beyin tümörlerinin hızlı ve doğru teşhis edilmesine yöneliktir. Beyin tümörleri başta çocuklar ve yaşlılar olmak üzere kanser hastalarının önde gelen ölüm nedenlerinden biridir. Özellikle son on yılda GPU hesaplama teknolojilerinin gelişmesi ve buna bağlı olarak derin öğrenme alanında yapılan çalışmaların artması da bu alana katkı sağlamıştır. Bu çalışmada MRI görüntüleri üzerinde 512x512 filtre boyutlarına sahip U-Net mimarisi kullanılarak beyin tümör hücrelerinin tespit edilmesini sağlayan bir sistem gerçekleştirilmiştir. Çalışmada literatürde sıkça kullanılan global verisetlerinden BRATS veriseti kullanılmıştır. Yapılan çalışma sonucunda güvenilirliği kabul edilebilen %91,38’lik bir dice skoru elde edilmiştir.</p></abstract>
                                                            
            
                                                                                        <kwd-group>
                                                    <kwd>Beyin tümörü segmentasyonu</kwd>
                                                    <kwd>  derin sinir ağları</kwd>
                                                    <kwd>  görüntü işleme</kwd>
                                                    <kwd>  U-net mimarisi</kwd>
                                            </kwd-group>
                            
                                                <kwd-group xml:lang="en">
                                                    <kwd>Brain tumor segmentation</kwd>
                                                    <kwd>  deep neural networks</kwd>
                                                    <kwd>  image processing</kwd>
                                                    <kwd>  U-net architecture</kwd>
                                            </kwd-group>
                                                                                                                                    <funding-group specific-use="FundRef">
                    <award-group>
                                                    <funding-source>
                                <named-content content-type="funder_name">Sakarya University of Applied Sciences Scientific Research Projects Coordination Unit</named-content>
                            </funding-source>
                                                                            <award-id>2021-01-09-039</award-id>
                                            </award-group>
                </funding-group>
                                </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">A. McNeill, “Epidemiology of Brain Tumors,” Neurologic Clinics, vol. 34, no. 4. W.B. Saunders, pp. 981–998, Nov. 01, 2016.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">Sazzad, M. Hoque, M. Rahman, and T. Ahmmed, Development of Automated Brain Tumor Identification Using MRI Images. IEEE, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">A. Zeineldin, M. E. Karar, J. Coburger, C. R. Wirtz, and O. Burgert, “DeepSeg: deep neural network framework for automatic brain tumor segmentation using magnetic resonance FLAIR images,” International Journal of Computer Assisted Radiology and Surgery, vol. 15, no. 6, pp. 909, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">Amin, M. Sharif, M. Yasmin, and S. L. Fernandes, “A distinctive approach in brain tumor detection and classification using MRI,” Pattern Recognition Letters, vol. 139, pp. 118–127, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">Atban and H. O. Ilhan, “MR görüntüleri üzerinden Alzheimer hastaliǧinin tespiti için Evrişimli Sinir Aǧ tasarimi ve performans kiyaslamasi,” in ISMSIT 2021 - 5th International Symposium on Multidisciplinary Studies and Innovative Tech., Proceedings, 2021.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">Deepak and P. M. Ameer, “Brain tumor classification using deep CNN features via transfer learning,” Computers in Biology and Medicine, vol. 111, no. June, p. 103345, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">Ito, K. Nakae, J. Hata, H. Okano, and S. Ishii, “Semi-supervised deep learning of brain tissue segmentation,” Neural Networks, vol. 116, pp. 25–34, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">T. Kebir and S. Mekaoui, “An Efficient Methodology of Brain Abnormalities Detection using CNN Deep Learning Network,” Proceedings of the 2018 International Conference on Applied Smart Systems, ICASS 2018, no. November, pp. 1–5, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">Mittal, L. M. Goyal, S. Kaur, I. Kaur, A. Verma, and D. Jude Hemanth, “Deep learning based enhanced tumor segmentation approach for MR brain images,” Applied Soft Computing Journal, vol. 78, pp. 346–354, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">M. Talo, U. B. Baloglu, Ö. Yıldırım, and U. Rajendra Acharya, “Application of deep transfer learning for automated brain abnormality classification using MR images,” Cognitive Systems Research, vol. 54, pp. 176–188, 2019.</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">B. Niepceron, A. Nait-Sidi-Moh, and F. Grassia, “Moving Medical Image Analysis to GPU Embedded Systems: Application to Brain Tumor Segmentation,” Applied Artificial Intelligence, vol. 34, no. 12, pp. 1–14, 2020.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">W. Zhang et al., “Deep convolutional neural networks for multi-modality isointense infant brain image segmentation,” NeuroImage, vol. 108, pp. 214–224, 2015.</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">O. Ronneberger, P. Fischer, and T. Brox, “U-Net: Convolutional Networks for Biomedical Image Segmentation,” 2015.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
