Kronik Böbrek Yetmezliği, Obezite ve Kanser Hastalarında Vitamin D Düzeyleri Üzerine Bir İnceleme

Year 2021, Volume: 4 Issue: 2, 52 - 60, 08.08.2021

Nilüfer Bulut , Fatma Ölmez Budak , Mehmet Çağatay Taşkapan

https://doi.org/10.33713/egetbd.951441

Cited By: 1

Abstract

Amaç: Çalışmamızda 2018-2021 yılları arasında Turgut Özal Tıp Merkezine başvuran obezite, kanser ve KBY tanılı hastaların yaş, cinsiyet ve mevsimlere göre vitamin D düzeylerinin dağılımının incelenmesi amaçlandı.
Gereç ve Yöntem: Tanımlayıcı tipte olan çalışmamızda 01.01.2018-01.01.2021 tarihleri arasında İnönü Üniversitesi (İÜ) Turgut Özal Tıp Merkezine başvuran obezite, kanser ve KBY tanılı vitamin D seviyeleri ölçülen hastaların dosyaları taranarak retrospektif olarak değerlendirildi. Hastalar örneklerin alındığı mevsimlere, cinsiyetlerine ve yaşlarına göre gruplandırıldı. 25(OH)D vitamini düzeyleri LC-MS/MS yöntemi ile analiz edildi. Hastalar vitamin D düzeyi bakımından eksik, yetersiz ve normal olanlar olarak sınıflandırıldı.
Bulgular: Hastanemize başvuran 1787 kanser hastasının %54,9’unda (n=981); 882 KBY hastasının %63,3’ünde (n=558) ve 2894 obezite hastasının %65,8’inde (n=1903) vitamin D eksikliği tespit edildi. Hastalıklara göre vitamin D düzeyleri arasında anlamlı bir fark vardı (p<0.001).
Sonuç: Hastanemize başvuran toplam 5563 obezite, kanser ve KBY hastasının; %61,9’unda (n=3442) vitamin D eksikliği, %23,1’inde (n=1284) vitamin D yetersizliği tespit edilirken, sadece %15'inde (n=837) vitamin D seviyesi normal olarak bulundu. Vitamin D eksikliği bakımından %57 oranla en fazla eksiklik obezite hastalarında görüldü. Çalışmamızda vitamin D düzeylerinin incelenen hastalıklara, mevsimlere ve yaş gruplarına bağlı olarak değiştiği görüldü.

Keywords

Vitamin D, kanser, kronik böbrek yetmezliği, obezite

Supporting Institution

Yok

Project Number

Yok

Retrospective Analysis of Vitamin D Levels in Patients with Chronic Renal Failure, Obesity, and Cancer

Abstract

OBJECTIVE: In our study, it was purposed to research the distribution of vitamin D according to age, sex, and seasons of the
patients diagnosed with obesity, cancer, and chronic renal failure who applied to Inonu University Turgut Ozal Medical Center
between 2018-2021.
MATERIALS AND METHODS: In our descriptive study, vitamin D measurements from 01.01.2018-01.01.2021 users who visited
Inonu University Turgut Ozal Medical Center and were diagnosed with obesity, cancer, and chronic renal failure were scanned in
their files and assessed retrospectively. The patients were grouped according to their sex, age, and seasons in which the samples
were taken. 25(OH)D levels were analyzed by LC-MS/MS method. The patients were classified as deficient, inadequate, and
normal in terms of vitamin D level
RESULTS: Vitamin D deficiency was monitored in 54.9% (n = 981) of 1787 cancer patients admitted to our hospital, 63.3% (n =
558) of 882 chronic renal failure patients, and 65.8% (n = 1903) of 2894 obese patients.
CONCLUSION: Of the 5563 obesity, cancer, and chronic renal failure patients who applied to our hospital; vitamin D deficiency
was found in 61.9% (n = 3442), vitamin D deficiency was found in 23.1% (n = 1284), while vitamin D level was found to be normal
in only 15% (n = 837). In terms of vitamin D deficiency, the highest deficiency was seen in obese patients with a rate 

Keywords

vitamin d, cancer, obesity

Project Number

Yok

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