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Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma

Year 2014, Volume: 11 Issue: 12, - , 21.03.2016
https://doi.org/10.15197/sabad.1.11.32

Abstract

The association between pancreas adenocarcinoma and breast infitrative ductal carcinoma is extremly rare. A 55-year-old woman was diagnosed as having a pancreatic adenocarcinoma. The patient underwent a Whipple operation. At the pathology consultation; result was well- differentiated adenocarcinoma, Six months later, patient came to routine polyclinic control with breast mass. After the true-cut biopsy, invasive ductal breast carcinoma was detected in pathological examination. The prosedure was breast conservation surgery and axillary lymph node dissection. We administered adjuvan chemotherapy and radiotherapy. We think that common genetic mechanism between pancreatic adenocarcinoma and breast infiltrative ductal carcinoma might be present. Clinicians should pay attention to the possibility associated breast cancer in preoperative screeening and follow up of patients with pancreatic adenocarcinoma.

References

  • O'Brien ME, Urbanski SJ. Coexisting pancreatic and breast adenocarcinomas: is there an association?. Pancreas 1986;1(2):191-4.
  • Minni F, Casadei R, Marrano N, et al. Second tumours in patients with malignant neoplasms of the digestive appa- ratus. A retrospective study on 2406 cases. Ann Ital Chir 2005;76(5):467-72.
  • Muroni M, D'Angelo F, Pezzatini M, et al. Synchronous gas- tric adenocarcinoma and pancreatic ductal adenocarci- noma. Hepatobiliary Pancreat Dis Int 2010;9(1):97-9.
  • Artac M, Bozcuk H, Ozdogan M, et al. Different clinical features of primary and secondary tumors in patients with multiple malignancies. Tumori 2005;91(4):317-20.
  • Eriguchi N, Aoyagi S, Hara M, et al. Synchronous or meta- chronous double cancers of the pancreas and other or- gans: report on 12 cases. Surg Today 2000;30(8):718-21.
  • Hiripi E, Lorenzo Bermejo J, Li X, Sundquist J, Hemminki K. Familial association of pancreatic cancer with other malignancies in Swedish families. Br J Cancer 2009 17;101(10):1792-7.
  • Couch FJ, Wang X, McWilliams RR, Bamlet WR, de Andrade M, Petersen GM. Association of breast cancer suscep- tibility variants with risk of pancreatic cancer. Cancer Epidemiol Biomarkers Prev 2009;18(11):3044-8.

Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma

Year 2014, Volume: 11 Issue: 12, - , 21.03.2016
https://doi.org/10.15197/sabad.1.11.32

Abstract

Pankreas adenokanseri ile memenin infiltratif duktal karinomu birlikteliği oldukça nadirdir. Ellibeş yaşında bir bayan hastaya pankeras adenokanseri tanısı ile Whipple operasyonu uygulandı. Histopatolojik inceleme sonucu iyi diferansiye adenokanser olarak rapor edildi. Altı ay sonra rutin poliklinik kontrolleri sırasında meme de kitle tespit edildi. Alınan trucut iğne biyopsisinde invaziv duktal meme kanseri saptandı. Hastaya meme koruyucu cerrahi ve aksiler lenf nodu diseksiyonu uygulandı. Operasyon sonrası adjuvan kemoterapi ve radyoterapi uygulandı. Pankreas adenokanseri ile memenin invaziv duktal karsinomu arasında genetik bir benzerlik olabileceğini düşünmekteyiz. Bu nedenle pankeras kanseri olan hastalarda meme kanseri görülebileceği ihtimali ile klinisyenler daha dikkatli olmaları gerekmektedir

References

  • O'Brien ME, Urbanski SJ. Coexisting pancreatic and breast adenocarcinomas: is there an association?. Pancreas 1986;1(2):191-4.
  • Minni F, Casadei R, Marrano N, et al. Second tumours in patients with malignant neoplasms of the digestive appa- ratus. A retrospective study on 2406 cases. Ann Ital Chir 2005;76(5):467-72.
  • Muroni M, D'Angelo F, Pezzatini M, et al. Synchronous gas- tric adenocarcinoma and pancreatic ductal adenocarci- noma. Hepatobiliary Pancreat Dis Int 2010;9(1):97-9.
  • Artac M, Bozcuk H, Ozdogan M, et al. Different clinical features of primary and secondary tumors in patients with multiple malignancies. Tumori 2005;91(4):317-20.
  • Eriguchi N, Aoyagi S, Hara M, et al. Synchronous or meta- chronous double cancers of the pancreas and other or- gans: report on 12 cases. Surg Today 2000;30(8):718-21.
  • Hiripi E, Lorenzo Bermejo J, Li X, Sundquist J, Hemminki K. Familial association of pancreatic cancer with other malignancies in Swedish families. Br J Cancer 2009 17;101(10):1792-7.
  • Couch FJ, Wang X, McWilliams RR, Bamlet WR, de Andrade M, Petersen GM. Association of breast cancer suscep- tibility variants with risk of pancreatic cancer. Cancer Epidemiol Biomarkers Prev 2009;18(11):3044-8.
There are 7 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

Mehmet Erikoglu This is me

Gürcan Simsek This is me

Çağlayan Geredeli This is me

Sakir Tavlı This is me

Publication Date March 21, 2016
Published in Issue Year 2014 Volume: 11 Issue: 12

Cite

APA Erikoglu, M., Simsek, G., Geredeli, Ç., Tavlı, S. (2016). Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma. European Journal of General Medicine, 11(12). https://doi.org/10.15197/sabad.1.11.32
AMA Erikoglu M, Simsek G, Geredeli Ç, Tavlı S. Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma. European Journal of General Medicine. March 2016;11(12). doi:10.15197/sabad.1.11.32
Chicago Erikoglu, Mehmet, Gürcan Simsek, Çağlayan Geredeli, and Sakir Tavlı. “Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma”. European Journal of General Medicine 11, no. 12 (March 2016). https://doi.org/10.15197/sabad.1.11.32.
EndNote Erikoglu M, Simsek G, Geredeli Ç, Tavlı S (March 1, 2016) Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma. European Journal of General Medicine 11 12
IEEE M. Erikoglu, G. Simsek, Ç. Geredeli, and S. Tavlı, “Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma”, European Journal of General Medicine, vol. 11, no. 12, 2016, doi: 10.15197/sabad.1.11.32.
ISNAD Erikoglu, Mehmet et al. “Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma”. European Journal of General Medicine 11/12 (March 2016). https://doi.org/10.15197/sabad.1.11.32.
JAMA Erikoglu M, Simsek G, Geredeli Ç, Tavlı S. Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma. European Journal of General Medicine. 2016;11. doi:10.15197/sabad.1.11.32.
MLA Erikoglu, Mehmet et al. “Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma”. European Journal of General Medicine, vol. 11, no. 12, 2016, doi:10.15197/sabad.1.11.32.
Vancouver Erikoglu M, Simsek G, Geredeli Ç, Tavlı S. Synchronous Pancreas Adenocarcinoma and Breast Infiltrative Ductal Carcinoma. European Journal of General Medicine. 2016;11(12).