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Medical management of deep vein thrombosis

Year 2009, Volume: 14 Issue: 2, 69 - 72, 14.01.2013

Abstract

Abstract. Making a diagnosis of deep vein thrombosis requires both clinical assessment and objective testing. Once a patient is diagnosed with an acute deep vein thrombosis, low-molecular- weight heparin  is the agent of choice for initial therapy and oral anticoagulant therapy is the standard for long-term secondary prophylaxis. Therapy should continue for at least 3 months; the decision to continue treatment beyond 3 months is made by weighing the risks of recurrent thrombosis and anticoagulant related bleeding, and is influenced by patient preference.

 

Key words: Thrombosis, vein, management

References

  • Gould MK, Dembitzer AD, Sanders GD, et al. Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A cost-effectiveness analysis. Ann Intern Med 1999; 130: 789-799.
  • Weitz JI. Low-molecular-weight heparins. N Engl J Med 1997; 337: 688-698.
  • Harrison L, Johnston M, Massicotte MP, et al Comparison of 5-mg and 10-mg loading doses in initiation of warfarin therapy. Ann Intern Med 1997; 126: 133-136.
  • Ansell J, Hirsh J, Dalen J, et al. Managing oral anticoagulant therapy. Chest 2001; 119: 22S-38S.
  • Levine MN, Raskob G, Landefeld S, et al. Hemorrhagic complications of anticoagulant treatment. Chest 2001; 119: 108S-121S.
  • Kearon C, Gent M, Hirsh J, et al. A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism. N Engl J Med 1999; 340: 901-907.
  • Schulman S, Rhedin AS, Lindmarker P, et al. A comparison of six weeks with six months of oral anticoagulant therapy after a first episode of venous thromboembolism. Duration of Anticoagulation Trial Study Group. N Engl J Med 1995; 332: 1661-1665.
  • Agnelli G, Prandoni P, Santamaria MG, et al. Three months versus one year of oral anticoagulant therapy for idiopathic deep venous thrombosis. Warfarin Optimal Duration Italian Trial Investigators. N Engl J Med 2001; 345: 165-169.
Year 2009, Volume: 14 Issue: 2, 69 - 72, 14.01.2013

Abstract

References

  • Gould MK, Dembitzer AD, Sanders GD, et al. Low-molecular-weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A cost-effectiveness analysis. Ann Intern Med 1999; 130: 789-799.
  • Weitz JI. Low-molecular-weight heparins. N Engl J Med 1997; 337: 688-698.
  • Harrison L, Johnston M, Massicotte MP, et al Comparison of 5-mg and 10-mg loading doses in initiation of warfarin therapy. Ann Intern Med 1997; 126: 133-136.
  • Ansell J, Hirsh J, Dalen J, et al. Managing oral anticoagulant therapy. Chest 2001; 119: 22S-38S.
  • Levine MN, Raskob G, Landefeld S, et al. Hemorrhagic complications of anticoagulant treatment. Chest 2001; 119: 108S-121S.
  • Kearon C, Gent M, Hirsh J, et al. A comparison of three months of anticoagulation with extended anticoagulation for a first episode of idiopathic venous thromboembolism. N Engl J Med 1999; 340: 901-907.
  • Schulman S, Rhedin AS, Lindmarker P, et al. A comparison of six weeks with six months of oral anticoagulant therapy after a first episode of venous thromboembolism. Duration of Anticoagulation Trial Study Group. N Engl J Med 1995; 332: 1661-1665.
  • Agnelli G, Prandoni P, Santamaria MG, et al. Three months versus one year of oral anticoagulant therapy for idiopathic deep venous thrombosis. Warfarin Optimal Duration Italian Trial Investigators. N Engl J Med 2001; 345: 165-169.
There are 8 citations in total.

Details

Primary Language English
Journal Section Letter to the Editor
Authors

Manoranjan Mahapatra This is me

Pravas Mishra This is me

Tulika Seth This is me

Renu Saxena This is me

Publication Date January 14, 2013
Published in Issue Year 2009 Volume: 14 Issue: 2

Cite

APA Mahapatra, M., Mishra, P., Seth, T., Saxena, R. (2013). Medical management of deep vein thrombosis. EASTERN JOURNAL OF MEDICINE, 14(2), 69-72.
AMA Mahapatra M, Mishra P, Seth T, Saxena R. Medical management of deep vein thrombosis. EASTERN JOURNAL OF MEDICINE. March 2013;14(2):69-72.
Chicago Mahapatra, Manoranjan, Pravas Mishra, Tulika Seth, and Renu Saxena. “Medical Management of Deep Vein Thrombosis”. EASTERN JOURNAL OF MEDICINE 14, no. 2 (March 2013): 69-72.
EndNote Mahapatra M, Mishra P, Seth T, Saxena R (March 1, 2013) Medical management of deep vein thrombosis. EASTERN JOURNAL OF MEDICINE 14 2 69–72.
IEEE M. Mahapatra, P. Mishra, T. Seth, and R. Saxena, “Medical management of deep vein thrombosis”, EASTERN JOURNAL OF MEDICINE, vol. 14, no. 2, pp. 69–72, 2013.
ISNAD Mahapatra, Manoranjan et al. “Medical Management of Deep Vein Thrombosis”. EASTERN JOURNAL OF MEDICINE 14/2 (March 2013), 69-72.
JAMA Mahapatra M, Mishra P, Seth T, Saxena R. Medical management of deep vein thrombosis. EASTERN JOURNAL OF MEDICINE. 2013;14:69–72.
MLA Mahapatra, Manoranjan et al. “Medical Management of Deep Vein Thrombosis”. EASTERN JOURNAL OF MEDICINE, vol. 14, no. 2, 2013, pp. 69-72.
Vancouver Mahapatra M, Mishra P, Seth T, Saxena R. Medical management of deep vein thrombosis. EASTERN JOURNAL OF MEDICINE. 2013;14(2):69-72.