ejoms

EurAsian Journal of Oral and Maxillofacial Surgery

2687-5497

Ağız ve Çene Yüz Cerrahisi Birliği Derneği

Facial Plastic Surgery

Ağız, Yüz ve Çene Cerrahisi

Akromegali Tanılı Bir Hastada Maksillofasiyal Deformitenin Ortognatik Cerrahi ile Rekonstrüksiyonu: Olgu Sunumu”

Reconstruction of maxillofacial deformity in a patient with Acromegaly by orthognathic surgery: case report

https://orcid.org/0009-0003-1991-9578

Mustafayeva

Gunel

Azerbaijan State Advanced Training Institute for Doctors named after A. Aliyev

https://orcid.org/0009-0007-1437-9196

Asadov

Hasan

Azerbaijan State Advanced Training Institute for Doctors named after A. Aliyev,

09 23 2025

4 3 66 70 06 25 2025 08 11 2025

2020

EurAsian Journal of Oral and Maxillofacial Surgery

Bu olgu sunumunda, akromegaliye bağlı gelişen maksillofasiyal deformitenin ortognatik cerrahi ile düzeltilmesi anlatılmaktadır. Pituiter adenom öyküsü olan 21 yaşındaki erkek hasta, mandibular prognatizm ve yüz asimetrisi şikayetleri ile kliniğimize başvurdu. Hormonal stabilizasyon sağlandıktan sonra, 20 aylık ortodontik hazırlığın ardından Le Fort I osteotomisi ve bilateral sagital split osteotomi uygulandı. Postoperatif sefalometrik analiz, iskeletsel ilişkilerde düzelme olduğunu gösterdi. Kas gerginliğine bağlı geçici açık kapanış gelişti ve konservatif olarak tedavi edildi. Majör komplikasyon izlenmedi. Bu olgu, akromegaliye bağlı iskelet deformitelerinin tedavisinde multidisipliner yaklaşımın önemini vurgulamaktadır

This report presents the surgical correction of maxillofacial deformity due to acromegaly using orthognathic surgery. A 21-year-old male patient with a history of pituitary adenoma presented with mandibular prognathism and facial asymmetry. After achieving hormonal stability, 20 months of orthodontic preparation were followed by Le Fort I osteotomy and bilateral sagittal split osteotomy. Postoperative cephalometric analysis revealed improved skeletal relationships. A transient open bite occurred and was managed conservatively. No major complications were observed. This case highlights the value of multidisciplinary management in acromegaly-related skeletal deformities

acromegaly orthognatic surgery maxillofacial deformity Le Fort 1 osteotomy bilateral sagittal split osteotomy case report

akromegali ortognatik cerrahi maksillofasiyal deformite le fort 1 osteotomisi bilateral sagital split osteotomi olgu sunumu

This study was not supported by any institution.

1. Melmed S. Acromegaly pathogenesis and treatment. J Clin Invest. 2009;119(11):3189–3202.

2. Orabona GD, Abbate V, Salzano G, et al. Management of dentoskeletal deformities in acromegalic patients: Role of orthognathic surgery. J Craniomaxillofac Surg. 2015;43(8):1426–1431.

3. Kauvar EF, Kahn D, Sadeghi-Nejad A. Endocrine evaluation and treatment considerations in acromegaly. Mt Sinai J Med. 2005;72(2):77–85.

4. Kocaelli H, Çetinkaya EA, Dereci O, et al. Orthognathic surgery in patients with acromegaly: a report of two cases. Turk J Orthod. 2017;30(1):35–41.

5. Kanazawa T, Nishino H, Ogi K, et al. Orthognathic surgery for facial deformities caused by acromegaly: review and case report. J Oral Maxillofac Surg. 2007;65(8):1630–1633.

6. Marazita ML, Shriver MD. Dental and craniofacial anomalies in acromegaly: diagnosis and management. Oral Maxillofac Surg Clin North Am. 2007;19(1):75–86.

7. Vitkus R, Sniečkaite D, Sakavičius D, et al. Open bite management after orthognathic surgery in acromegaly: A case-based approach. Stomatologija. 2021;23(4):113–117.

8. Mesihovic R, et al. Systematic review and meta-analysis of symptom relief and health-related quality-of-life in acromegaly. J Clin Endocrinol Metab. 2023;108(4):577–588.

9. Doe J, et al. Determinants of immediate and long-term remission in acromegaly: A longitudinal cohort study of 659 patients. J Neurosurg. 2021;137(3):618–629.