Siklobütan Halkası İçeren Schiff Bazı ve Metal Komplekslerinin Sentezi ve Antimikrobiyal Aktivite Çalışmaları

Year 2019, Issue: 17, 437 - 444, 31.12.2019

İbrahim Yılmaz Alaaddin Çukurovalı

https://doi.org/10.31590/ejosat.621366

Abstract

Bu çalışmada yapısında
siklobütan grubu bulunan tiyosemikarbazon türevi Schiff bazı ve bunun nikel,
bakır ve çinko kompleksleri sentezlenmiştir. Sentezlenen bileşiklerin
saflaştırılması kristallendirme ve kolon kromatografisi ile yapılmıştır.
Karakterizasyon işlemlerinde ise IR, ¹H NMR, ¹³C NMR ve
elementel analiz gibi enstrümental analiz yöntemleri kullanılmıştır. Sentezlenen
komplekslerin mononükleer olduğu ve ML₂ yapısında olduğu
bulunmuştur. Ayrıca, sentezlenen bileşiklerin farklı mikroorganizmalara karşı
antimikrobiyal etkileri araştırılmıştır.

Keywords

Schiff Bazı, Siklobütan, Metal Kompleksleri, Antimikrobiyal Aktivite

Supporting Institution

Karamanoğlu Mehmetbey Üniversitesi

Project Number

30-M-16

Thanks

Bu çalışma Karamanoğlu Mehmetbey Üniversitesi Bilimsel Araştırma Projeleri Birimi tarafından 30-M-16 numaralı proje tarafından desteklenmiştir.

Synthesis and Antimicrobial Activity Studies of Cyclobutane Ring Containing Schiff Base and their Metal Complexes

Abstract

In this study, thiosemicarbazone derivative Schiff base containing
cyclobutane group and their Cu(II), Ni(II) ve Zn(II) complexes were synthesised
and characterized. Purification of the synthesised compounds were carried out
with crystallography and column cromatography techniques. In the
characterization of the Schiff base and their complexes, IR, ¹H NMR,
¹³ C NMR spectral techniques and elemental analysis were used. All the complexes
were found to be mononuclear and ML₂ form. Besides, antimicrobial
activities of the Schiff base and its transition metal complexes have been
tested different microorganisms.

Keywords

Schiff Bases, Cyclobutane, Metal Complexes, Antimicrobial Activty

Project Number

30-M-16

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