Heterotopic gastric mucosa prevalence, clinical importance and associated endoscopic findings

Year 2014, , 60 - 63, 01.12.2014

Nurten Savaş Enver Akbaş

https://doi.org/10.17940/endoskopi.74772

Cited By: 1

Abstract

Background and Aims:In this retrospective study our aim was to find the prevalance of heterotopic gastric mucosa, evaluate its clinical importance, and study the endoscopic findings associated with heterotopic gastric mucosa in patients with diffrerent indications for gastrointestinal endoscopy. Materials and Methods:This study comprised 3.384 patients who were referred to our hospital's gastroenterology department with different complaints and to whom upper gastrointestinal endoscopy was performed during 2009-2013. Heterotopic gastric mucosa prevalance, endoscopic findings associated with heterotopic gastric mucosa, the main complaints of patients with heterotopic gastric mucosa and endoscopic biopsy findings were recorded. Results:Out of 3.384 patients, heterotopic gastric mucosa was found in 86 (2.5%) patients. Endoscopic findings associated with heterotopic gastric mucosa was as follows: Reflux esophagitis in 22 (25.5%) patients; lower esophageal sphincter dysfunction in 7 (8.1%) patients; hiatal hernia in 10 (11.6%) patients; Barrett esophagus in 5 (5.8%) patients; cardiac cancer in 1 (1.1%) patient; esophageal gastrointestinal stromal tumor in 1 (1.1%) patient; peptic ulcer in 7 (%8.1) patients; and gastritis in 74 (86%) patients. The primary complaints of patients with heterotopic gastric mucosa included: retrosternal pain and/ or regurgitation in 28 (32.5%) patients; dysphagia in 17(19.7%) patients; dyspepsia in 35 (40.6%) patients; and laryngopharengial reflux symptoms in 6 (6.9%) patients. The endoscopic biopsy of antrum mucosa revealed that 26 (30%) patients had Helicobacter pyloriinfection. Conclusion:Heterotopic gastric mucosa prevalance was 2.5% in our patients. Half of our patients presented with dysphagia or reflux symptoms. Barrett esophagus prevalance was 5.8%, which is relatively higher, supporting the relationship between heterotopic gastric mucosa and Barrett esophagus.

Keywords

Heterotopic gastric mucosa, inlet patch, reflux

Heterotopik gastrik mukozanın sıklığı, klinik önemi ve eşlik eden diğer klinik bulgular

Abstract

Giriş ve Amaç:Bu retrospektif çalışmada heterotopik gastrik mukozanın sıklığı, klinik önemi ve heterotopik gastrik mukozaya eşlik eden diğer endoskopik bulguların araştırılması amaçlanmıştır. Gereç ve Yöntem:2009-2013 yılları arasında çeşitli şikayetler ile Gastroenteroloji polikliğimize başvuran ve üst gastrointestinal sistem endoskopisi yapılan 3.384 olgu çalışmaya alınmıştır. Olgulardaki heterotopik gastrik mukoza varlığı, eşlik eden diğer endoskopik bulgular, endoskopik biyopsi patoloji sonuçları ve hastaların başvuru şikayetleri değerlendirilmiştir. Bulgular:Çalışmaya alınan 3.384 olgunun 86'sında (%2.5) özofagusta heterotopik gastrik mukoza ile uyumlu lezyon saptanmış olup, heterotopik gastrik mukozalı hastaların 22'sinde eşlik eden reflü özofajit bulgusu (%25.5), 7'sinde üst özofageal sfinkter disfonksiyonu (%8.1), 10'unda hiatal herni (%11.6), 5'inde Barrett özofagus (%5.8), 1'inde kardiya tümörü (%1.1), 1'inde (%1.1) özofageal gastrointestinal submukozal tümör, 7'sinde (%8.1) peptik ülser ve 74'ünde (%86) gastrit saptanmıştır. Heterotopik gastrik mukozalı hastaların 28'inde (%32.5) retrosternal yanma ve/veya regürjitasyon, 17'sinde (%19.7) disfaji, 35'inde (%40.6) dispeptik yakınmalar ve 6'sında (%6.9) larengofarengeal reflü yakınmaları mevcut idi. Hastalardan alınan endoskopik antrum biyopsilerin 26'sında (%30) Helicobacter pylori enfeksiyonu saptanmıştır. Sonuç:Üst gastrointestinal sistem endoskopisi yapılan hastalarımızın %2.5'inde özofagusta heterotopik gastrik mukoza saptanmış olup bu hastaların yüzde 50'si disfaji ya da reflü şikayeti ile kliniğe başvuran hastalardır. Barrett özofagus sıklığı %5.8 olarak bulunmuş olup nispeten yüksek olan bu oran heterotopik gastrik mukoza ile Barrett özofagus arasındaki ilişkiyi destekler niteliktedir.

Keywords

Heterotopik gastrik mukoza, gastrik inlet patch, reflü

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