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            <front>

                <journal-meta>
                                    <journal-id></journal-id>
            <journal-title-group>
                                                                                    <journal-title>Erzincan University Journal of Science and Technology</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2149-4584</issn>
                                                                                            <publisher>
                    <publisher-name>Erzincan Binali Yildirim University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.18185/erzifbed.466402</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Engineering</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Mühendislik</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Comparative Anatomical Studies on Three Tanacetum L. Taxa (Asteraceae) Growing in Turkey</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="tr">
                                    <trans-title>Türkiye’de Yetişen Üç Tanacetum L. Taksonu (Asteraceae) Üzerinde Karşılaştırmalı Anatomik Çalışmalar</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-3986-4909</contrib-id>
                                                                <name>
                                    <surname>Arıtuluk</surname>
                                    <given-names>Zekiye Ceren</given-names>
                                </name>
                                                                    <aff>Hacettepe Üniversitesi</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Gençler Özkan</surname>
                                    <given-names>Ayşe Mine</given-names>
                                </name>
                                                                    <aff>Ankara Üniversitesi</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                <name>
                                    <surname>Ezer</surname>
                                    <given-names>Nurten</given-names>
                                </name>
                                                                    <aff>Hacettepe Üniversitesi</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20190324">
                    <day>03</day>
                    <month>24</month>
                    <year>2019</year>
                </pub-date>
                                        <volume>12</volume>
                                        <issue>1</issue>
                                        <fpage>336</fpage>
                                        <lpage>348</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20181001">
                        <day>10</day>
                        <month>01</month>
                        <year>2018</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20190308">
                        <day>03</day>
                        <month>08</month>
                        <year>2019</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2008, Erzincan University Journal of Science and Technology</copyright-statement>
                    <copyright-year>2008</copyright-year>
                    <copyright-holder>Erzincan University Journal of Science and Technology</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Tanacetum L. (Asteraceae) is a complex genus represented by 160 species in theworld and 47 species in our country. Tanacetumparthenium (L.) Sch.Bip., among the species of this genus which have beenused in traditional treatments, is an official species registered in manypharmacopoeia and monographs due to its parthenolide content. Studies haveshown that subspecies of T. argenteum (Lam.) Willd. also contain parthenolide as themajor active constituent. In this study, besides the well known T. parthenium, the anatomical characteristics ofparthenolide-containing taxa with therapeuticpotential; T. argenteum (Lam.) Willd. ssp. canum(C.Koch) var. pumilum and T. argenteum (Lam.) Willd. ssp. flabellifolium (Boiss. &amp;amp; Heldr.)Grierson were also investigated for the first time. The transverse andsuperficial sections taken from the stems and leaves of the taxa were examinedby light microscope and specific anatomical features were defined. Uniserial,multicellular covering hairs on stem and leaf surface and bifacial leaf structureare the most prominent characters that distinguish T. parthenium from other studied taxa. There was no significantanatomical difference found between the two infraspecific taxa of T. argenteum.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="tr">
                            <p>Tanacetum L. (Asteraceae) dünyada160 kadar, ülkemizde ise 47 tür ile temsil edilen kompleks bir cinstir.Geleneksel tedavide kullanılan birçok türe sahip bu cinsin türleri arasında yeralan Tanacetum parthenium (L.) Sch.Bip., içeriğinde bulunanpartenolit nedeniyle birçok farmakope ve monografta kayıtlı ofisinal birtürdür. Yapılan çalışmalar, T. argenteum (Lam.) Willd.’in alttürlerinde de temel aktif bileşik olarak partenolit olduğunugöstermiştir. Bu çalışmada, yaygın olarak bilinen T. parthenium yanında, partenolit içeriğinedeniyle tıbbi bitki potansiyeline sahip olan ve daha önce üzerinde anatomikbir çalışmaya rastlamadığımız T. argenteum (Lam.) Willd. ssp. canum (C.Koch) var. pumilum ve T. argenteum (Lam.) Willd. ssp. flabellifolium(Boiss. &amp;amp; Heldr.) Grierson taksonlarının anatomiközellikleri araştırılmıştır. Taksonların gövde ve yapraklarından alınan enine ve yüzeysel kesitlerışık mikroskobu ile incelenmiş ve anatomik karakterler tanımlanmıştır. Gövde veyaprak yüzeyinde bulunan tek sıralı, çok hücreli örtü tüyleri ile bifasyalyaprakları T. parthenium’u çalışılandiğer taksonlardan ayıran en belirgin anatomik karakterlerdir. T. argenteum’un iki alt türü arasındaanatomik olarak belirgin bir fark olmadığı tespit edilmiştir.</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Tanacetum</kwd>
                                                    <kwd>  stem</kwd>
                                                    <kwd>  leaf</kwd>
                                                    <kwd>  plant anatomy</kwd>
                                                    <kwd>  Asteraceae</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="tr">
                                                    <kwd>Tanacetum</kwd>
                                                    <kwd>  gövde</kwd>
                                                    <kwd>  yaprak</kwd>
                                                    <kwd>  bitki anatomisi</kwd>
                                                    <kwd>  Asteraceae</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
    <back>
                            <ref-list>
                                    <ref id="ref1">
                        <label>1</label>
                        <mixed-citation publication-type="journal">Abad, M. J., Bermejo, P. and Villar, A. 1995. “An approach to the genus Tanacetum L. (Compositae): phytochemical and pharmacological review”, Phytotherapy Research, 9(2), 79-92.</mixed-citation>
                    </ref>
                                    <ref id="ref2">
                        <label>2</label>
                        <mixed-citation publication-type="journal">Arıtuluk, Z. C. 2016. “Antalya’da yetişen Tanacetum L. (Asteraceae) cinsine ait taksonlar üzerinde araştırmalar”, Yayımlanmamış Doktora Tezi, Ankara Üniversitesi Sağlık Bilimleri Enstitüsü, Ankara, 224-227.</mixed-citation>
                    </ref>
                                    <ref id="ref3">
                        <label>3</label>
                        <mixed-citation publication-type="journal">Chaves, J. S. and Da Costa, F. B. 2008. “A proposal for the quality control of Tanacetum parthenium (feverfew) and its hydroalcoholic extract”, Revista Brasileira de Farmacognosia, 18(3), 360-366.</mixed-citation>
                    </ref>
                                    <ref id="ref4">
                        <label>4</label>
                        <mixed-citation publication-type="journal">Ciccarelli, D., Garbari, F. and Pagni, A. M. 2007. “Glandular hairs of the ovary: a helpful character for Asteroideae (Asteraceae) taxonomy?”, Annales Botanici Fennici, 44, 1-7.</mixed-citation>
                    </ref>
                                    <ref id="ref5">
                        <label>5</label>
                        <mixed-citation publication-type="journal">Çelebioğlu, S. and Baytop, T. (1949). “Bitkisel tozların tetkiki için yeni bir reaktif”, Farmakognozi Enstitüsü Yayınları, İstanbul, 19-301.</mixed-citation>
                    </ref>
                                    <ref id="ref6">
                        <label>6</label>
                        <mixed-citation publication-type="journal">Davis, P. (1975). “Flora of Turkey and the East Aegean Islands”, Edinburgh University Press, Edinburgh, Vol. 5.</mixed-citation>
                    </ref>
                                    <ref id="ref7">
                        <label>7</label>
                        <mixed-citation publication-type="journal">Erdogan Orhan, I., Tosun, F., Gulpinar, A. R., Kartal, M., Duran, A., Mihoglugil, F. and Akalgan, D. 2015. “LC-MS quantification of parthenolide and cholinesterase inhibitory potential of selected Tanacetum L. (Emend. Briq.) taxa”, Phytochemistry Letters, 11, 347-352.</mixed-citation>
                    </ref>
                                    <ref id="ref8">
                        <label>8</label>
                        <mixed-citation publication-type="journal">European Pharmacopoeia (2014). “Tanaceti parthenii herba 8th ed., Council of Europe, Strasbourg.</mixed-citation>
                    </ref>
                                    <ref id="ref9">
                        <label>9</label>
                        <mixed-citation publication-type="journal">Gören, N., Arda, N. and Çaliskan, Z. (2002). “Chemical characterization and biological activities of the genus Tanacetum (Compositae)”, Studies in Natural Products Chemistry, Elsevier, Vol. 27, Part H, 547-658.</mixed-citation>
                    </ref>
                                    <ref id="ref10">
                        <label>10</label>
                        <mixed-citation publication-type="journal">Grierson, A. (1975). “Tanacetum L.”, Flora of Turkey and the East Aegean Islands, Edinburgh University Press, Edinburgh, Vol. 5, 256-292.</mixed-citation>
                    </ref>
                                    <ref id="ref11">
                        <label>11</label>
                        <mixed-citation publication-type="journal">Güner, A., Aslan, S., Ekim, T., Vural, M. and Babaç, M. (2012). “Türkiye Bitkileri Listesi (Damarli Bitkiler)”, ANG Vakfi, Nezahat Gökyiğit Botanik Bahçesi Yayınları. İstanbul, 203-207.</mixed-citation>
                    </ref>
                                    <ref id="ref12">
                        <label>12</label>
                        <mixed-citation publication-type="journal">Kodak, E., Pinar, N. M., Adigüzel, N. and Acar, A. 2012. “Pollen morphology of some taxa of genus Tanacetum L.(Asteraceae) in Turkey”, Mellifera, 12(24), 2-10.</mixed-citation>
                    </ref>
                                    <ref id="ref13">
                        <label>13</label>
                        <mixed-citation publication-type="journal">Korkmaz, M., Kandemir, A., İlhan, V. and Yıldırımlı Doğan, N. 2015. “Tanacetum erzincanense (Asteraceae), a new species from Erzincan, Turkey”, Turkish Journal of Botany, 39(1), 96-104.</mixed-citation>
                    </ref>
                                    <ref id="ref14">
                        <label>14</label>
                        <mixed-citation publication-type="journal">Kreuger, M. R. O., Grootjans, S., Biavatti, M. W., Vandenabeele, P. and D’Herde, K. 2012. “Sesquiterpene lactones as drugs with multiple targets in cancer treatment: focus on parthenolide”, Anti-Cancer Drugs, 23(9), 883-896.</mixed-citation>
                    </ref>
                                    <ref id="ref15">
                        <label>15</label>
                        <mixed-citation publication-type="journal">Mathema, V. B., Koh, Y. S., Thakuri, B. C. and Sillanpaa, M. 2012. “Parthenolide, a sesquiterpene lactone, expresses multiple anti-cancer and anti-inflammatory activities”, Inflammation, 35(2), 560-565.</mixed-citation>
                    </ref>
                                    <ref id="ref16">
                        <label>16</label>
                        <mixed-citation publication-type="journal">Metcalfe, C. R. and Chalk, L. (1950). “Anatomy of the Dicotyledons 2nd ed.” Clarendon Press, Oxford, London, Vol. 2.</mixed-citation>
                    </ref>
                                    <ref id="ref17">
                        <label>17</label>
                        <mixed-citation publication-type="journal">Özmen, E., Kızılpınar, I., Özudoğru, B., Doğan, C. and Erik, S. 2009. “Pollen morphology of some taxa of aromatic genus Tanacetum L. (Asteraceae)”, Journal of Pharmaceutical Sciences, 34, 1-11.</mixed-citation>
                    </ref>
                                    <ref id="ref18">
                        <label>18</label>
                        <mixed-citation publication-type="journal">Pareek, A., Suthar, M., Rathore, G. S., and Bansal, V. 2011. “Feverfew (Tanacetum parthenium L.): A systematic review”, Pharmacognosy Reviews, 5(9), 103–110.</mixed-citation>
                    </ref>
                                    <ref id="ref19">
                        <label>19</label>
                        <mixed-citation publication-type="journal">Rahfeld, B. (2009). “Mikroskopischer Farbatlas pflanzlicher Drogen”, Spektrum Akademischer Verlag, Heidelberg, 104-105.</mixed-citation>
                    </ref>
                                    <ref id="ref20">
                        <label>20</label>
                        <mixed-citation publication-type="journal">Rahman, A., Alam, M., Hossain, M., Nesa, M., Islam, A., and Rahman, M. M. 2008. “Study of Species Diversity on the family Asteraceae (Compositae) of the Rajshahi Division”, Research Journal of Agriculture and Biological Sciences, 4(6), 794-797.</mixed-citation>
                    </ref>
                                    <ref id="ref21">
                        <label>21</label>
                        <mixed-citation publication-type="journal">Simmons, C., Raj, S. K. and Saxena, P. 2002. “Morphocytological characterization of feverfew, Tanacetum parthenium (L.) Schultz Bip.”, Journal of Herbs, Spices &amp; Medicinal plants, 9(1), 29-45.</mixed-citation>
                    </ref>
                                    <ref id="ref22">
                        <label>22</label>
                        <mixed-citation publication-type="journal">Sonboli, A. and Oberprieler, C. 2012. “Insights into the phylogenetic and taxonomic position of Tanacetum semenovii Herder (Compositae, Anthemideae) based on nrDNA ITS sequences data”, Biochemical Systematics and Ecology, 45, 166-170.</mixed-citation>
                    </ref>
                                    <ref id="ref23">
                        <label>23</label>
                        <mixed-citation publication-type="journal">Tekin, M. and Kartal, Ç. 2016. “Comparative anatomical investigations on six endemic Tanacetum (Asteraceae) taxa from Turkey”, Pakistan Journal of  Botany, 48(4), 1501-1515.</mixed-citation>
                    </ref>
                                    <ref id="ref24">
                        <label>24</label>
                        <mixed-citation publication-type="journal">Upton, R., Graff, A., Jolliffe, G., Länger, R. and Williamson, E. (2011). “American Herbal Pharmacopoeia: Botanical Pharmacognosy-Microscopic Characterization of Botanical Medicines”, CRC Press, New York.</mixed-citation>
                    </ref>
                            </ref-list>
                    </back>
    </article>
