KÖPEK VE KEDİLERDE EPİLEPSİ

Year 2020, Volume 29, Issue 3, 222 - 227, 30.11.2020

Mehmet Akif RIHTIM Öznur ASLAN

https://doi.org/10.34108/eujhs.754285

Abstract

Epilepsi serebral kortekste, inhibisyon ve eksitasyon dengesizliği sonucu hipersenkronize nöronal aktivite nedeniyle oluşan ve nöbetlerle ortaya çıkan bir merkezi sinir sistemi hastalığıdır. Epilepsi tedavisinde kullanılacak ilaçlar ve hastalığın prognozunu belirlemek için nöbetler sınıflandırılmalıdır. Epilepsi nöbetleri, klinik belirtileri ve etiyolojileri olmak üzere iki farklı şekilde sınıflandırılırlar. Bu derlemenin amacı, veteriner hekimliğinde epilepsinin anlaşılmasını sağlamak ve tanı, tedavi ve prognoz açısından önemli olan sınıflandırma hakkında bilgi vermektir.

Keywords

Epilepsi, kedi, köpek, sınıflandırma

EPILEPSY IN CANINE AND FELINE

Abstract

Epilepsy is a central nervous system disease, caused by hyper-synchronous neuronal activity in the cerebral cortex as a result of inhibition and excitation imbalance. To determine the prognosis of the disease and its seizures, drugs, which are used in epilepsy treatment, should be classified. Epileptic seizures are classified in two different ways, according to their clinical symptoms and etiology. The purpose of this review is to provide an understanding of epilepsy in veterinary medicine, and to provide information about the classification, which is important for diagnosis, treatment and prognosis.

Keywords

Canine,, classification,, epilepsy, feline.

References

• Scharfman HE. The neurobiology of epilepsy. Current Neurology and Neuroscience Reports 2007; 7:348-354.
• Barnes HH. Feline Epilepsy. The Veterinary Clinics of North America. Small Animal Practice 2018; 48:31-43.
• Berg AT, Berkovic SF, Brodie MJ, et al. Revised terminology and concepts for organization of seizures and epilepsies: report of the ILAE Commission on Classification and Terminology, 2005-2009. Epilepsia 2010; 51:676-685.
• Angeles DK. Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia 1981; 22:489-501.
• Commission on Classification and Terminology of the International League Against Epilepsy. Proposal for revised classification of epilepsies and epileptic syndromes, Epilepsia, 1989; 30:4:389-399.
• Engel JrJ. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology. Epilepsia 2001; 42:796-803.
• Engel JrJ. Report of the ILAE classification core group. Epilepsia 2006; 47:1558-1568.
• Schwartz-Porsche D. Seizures. In: Kyle G. Braund (ed) Clinical Syndromes in Veterinary Neurology (2 nd ed). Elsevier Health Sciences, London 1994; 2: pp 234-251.
• Berendt M, Gram L. Epilepsy and seizure classification in 63 dogs: a reappraisal of veterinary epilepsy terminology. Journal of Veterinary Internal Medicine 1999; 13:14-20.
• 1Licht BG, Licht MH, Harper KM, et al. Clinical presentations of naturally occurring canine seizures: similarities to human seizures. Epilepsy & Behavior 2002; 3:460-470.
• Berendt M. Epilepsy. ‘’https://www.ivis.org/library/braunds-clinical-neurology-small-animals-localization-diagnosis-and-treatment/epilepsy’’ Erişim: 10 Haziran 2020.
• Platt S. and Olby N. BSAVA Manual of Canine and Feline Neurology. BSAVA, 2004; pp 97-112.
• Thomas WB. Idiopathic epilepsy in dogs and cats. Veterinary Clinics: Small Animal Practice 2010; 40.1:161-179.
• Berendt M, Farquhar RG, Mandigers PJ, et al. International veterinary epilepsy task force consensus report on epilepsy definition, classification and terminology in companion animals. BMC Veterinary Research 2015; 11.1:182.
• Schwartz-Porsche D, Kaiser E. Feline epilepsy. Problems in Veterinary Medicine 1989; 1:628-649.
• Schriefl S, Steinberg TA, Matiasek K, et al. Etiologic classification of seizures, signalment, clinical signs, and outcome in cats with seizure disorders: 91 cases (2000–2004). Journal of the American Veterinary Medical Association 2008; 233:1591-1597.
• Risio DL. and Platt S. Canine and Feline Epilepsy Diagnosis and Management. CABI, Oxfordshire, 2014; pp 43.
• Heynold Y, Faissler D, Steffen F, et al. Clinical, epidemiological and treatment results of idiopathic epilepsy in 54 Labrador retrievers: a long‐term study. Journal of Small Animal Practice 1997; 38.1:7-14.
• Licht BG, Lin S, Luo Y, et al. Clinical characteristics and mode of inheritance of familial focal seizures in Standard Poodles. Journal of the American Veterinary Medical Association 2007; 231:1520-1528.
• Jian Z, Alley MR, Cayzer J, et al. Lafora's disease in an epileptic Basset hound. New Zealand Veterinary Journal 1990; 38:75-79.
• Fitzmaurice SN, Rusbridge C, Shelton GD, et al. Familial myoclonic epilepsy in the miniature wirehaired dachshund. J Vet Intern Med 2001; 15:72-73.
• Gredal H, Berendt M, Leifsson PS. Progressive myoclonus epilepsy in a beagle. Journal of Small Animal Practice 2003; 44:511-514.
• Davis KE, Finnie JW, Hooper PT. Lafora's disease in a dog. Australian Veterinary Journal 1990; 67:192-193.
• Schoeman T, Williams J, van Wilpe E. Polyglucosan storage disease in a dog resembling Lafora's disease. Journal of Veterinary Internal Medicine 2002; 16:201-207.
• Webb AA, McMillan C, Cullen CL, et al. Lafora disease as a cause of visually exacerbated myoclonic attacks in a dog. The Canadian Veterinary Journal 2009; 50:963.
• Podell M. Tremor fasciculations, and movement disorders. Veterinary Clinics: Small Animal Practice 2004; 34:1435-1452.
• Barnes HL, Chrisman CL, Mariani CL, et al. Clinical signs, underlying cause, and outcome in cats with seizures: 17 cases (1997–2002). Journal of the American Veterinary Medical Association 2004; 225:1723-1726.
• Poma R, Ochi A, Cortez MA. Absence seizures with myoclonic features in a juvenile Chihuahua dog. Epileptic Disorders 2010; 12:138-141.
• Quesnel AD, Parent JM, McDonell W, et al. Diagnostic evaluation of cats with seizure disorders: 30 cases (1991-1993). Journal of the American Veterinary Medical Association 1997; 210:65-71.
• Risio DL, Platt S. Canine and Feline Epilepsy Diagnosis and Management. CABI, Oxfordshire, 2014; pp 44.
• Breitschwerdt EB, Breazile JE, Broadhurst JJ. Clinical and electroencepahlographic findings associated with ten cases of suspected limbic epilepsy in the dog. Journal American Animal Hospital Association 1979; 15:37-50.
• Berendt M, Gredal H, Alving J. Characteristics and phenomenology of epileptic partial seizures in dogs: similarities with human seizure semiology. Epilepsy Research 2004; 61:167-173.
• Stonehewer J, Mackin AJ, Tasker S, et al. Idiopathic phenobarbital‐responsive hypersialosis in the dog: an unusual form of limbic epilepsy? Journal of Small Animal Practice 2000; 41:416-421.
• Gibbon KJ, Trepanier LA, Delaney FA. Phenobarbital-responsive ptyalism, dysphagia, and apparent esophageal spasm in a German shepherd puppy. Journal of the American Animal Hospital Association 2004; 40:230-237.
• Podell M, Fenner WR, Powers JD. Seizure classification in dogs from a nonreferral-based population. Journal of the American Veterinary Medical Association 1995; 206:1721-1728.
• Jull P, Risio LD, Horton C, et al. Effect of prolonged status epilepticus as a result of intoxication on epileptogenesis in a UK canine population. Veterinary Record 2011: 169;361.
• Kuwabara T, Hasegawa D, Ogawa F, et al. A familial spontaneous epileptic feline strain: a novel model of idiopathic/genetic epilepsy. Epilepsy Research 2010; 92:85-88.
• Patterson EE, Mickelson JR Da Y, et al. Clinical characteristics and inheritance of idiopathic epilepsy in Vizslas. Journal of Veterinary Internal Medicine 2003; 17:319-325.
• Berendt M, Gulløv CH, Fredholm M. Focal epilepsy in the Belgian shepherd: evidence for simple Mendelian inheritance. Journal of Small Animal Practice 2009; 50:655-661.
• Pákozdy Á, Leschnik M, Sarchahi AA, et al. Clinical comparison of primary versus secondary epilepsy in 125 cats. Journal of Feline Medicine and Surgery 2010; 12:910-916.
• Berendt M, Gulløv CH, Christensen SLK, et al. Prevalence and characteristics of epilepsy in the Belgian shepherd variants Groenendael and Tervueren born in Denmark 1995–2004. Acta Veterinaria Scandinavica 2008; 50:51.
• Thomas WB. Evaluation of veterinary patients with brain disease. Veterinary Clinics: Small Animal Practice 2010; 40:1-19.
• Risio DL. and Platt S. Canine and Feline Epilepsy Diagnosis and Management. CABI, Oxfordshire, 2014.