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AFLATOKSİN VE AFLATOKSİN BAĞLAYICISI OLAN POLİVİNİLPOLİPİROLİDON (PVPP) VERİLEN BROİLERLERDE PERİTONEAL MAKROFAJLARIN FAGOSİTİK VE MiKROBiSİDAL AKTİVİTELERİNİN BELİRLENMESİ

Year 1996, Volume: 12 Issue: 1, 145 - 151, 01.03.1996

Abstract

Bu çalışmada yemle 21 gün süreyle 2, 5 mg/kg yem düzeyinde karışık aflatoksin verilerek oluşturulan deneysel allatoksıkozıste ellık cıvcıvlerın peritoneal makrofajlarının fagositik ve Candidasidal etkinilklerı ile yeme 3 g/kg dli zeyınde ılave edılen polivinıl polıpırolıdon (PVPP)'un koruyucu etkisi araştırıldı.Yedirme denemelerı 200 adetAvian ırkı, günlük erkek etçi cıvcıvde gerçekleştirildi. Hayvanlar, herbirinde SO'şer civciv bulunan 4 gruba ayrıldı ve aşagıdakı yemlerle beslendi: Birinci grup ticari etlik piliç yemiyle, ikinci grup 2.5 mg/kg düzeyinde aflatoksin Içeren ticarı etlik piliç yeınıyle, üçuncü grup% 0.3 oranında PVPP ilave edilen tıcarı etlik pilıç yemlyle, dördOnca grup "'o O, 3 oranında PVPP ve 2.5 mg/kg düzeyinde aflatoksin içeren ticari etlik piliç yemiyle. Yedirme denemesi sonunda, peritoneal mak· rofajlar elde edildi. Fagositik ve Candidasidal indeksler belirlendi. Sonuçlar istatıstiksel metodlarla analız edildi. So­nuçlar. aflatoksıkozısin makrofajların hem fagositoz ve hem de Candidasidal güçlerini baskıladı�ını ortaya koy­maktadır. PVPP ilavesi hayvanları. aflatoksinlerin peritoneal makrofajların görevlerınde neden olduğu baskılamadan korumaktadır

Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages lsolated from Chickens Fed with Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed

Year 1996, Volume: 12 Issue: 1, 145 - 151, 01.03.1996

Abstract

In thıs study effects of aflatoxlcosis. which was experımentally induced by giving mixed aflatoxins ın feed (2. 5 mg/kg) for 21 days. on phagocytic and Candidacidal activities of chicken peritoneal macrophages and pre· ventıve actıon ol polyvinylpolypyrrolidone (PVPP) supplementation (3g/kg) were investigated. Feeding experıments were performed on totally 200 mala one·day·old chlcks of Avlan strain. The animals were divided into tour groups each containing 50 chickens and leed with dilterant diets as fallows: First group, with commercial broıler feed. Se­cond group, wıth mixed aflatoxıns containing (2.5 mg/kg) commercial broiler feed Third group, wıth PVPP (0.3 %) supplemented commercial broiler feed. Fourth group, with both PVPP (0.3 %) and mixed aflatoxıns (2.5 mgfkg) con· taınıng feed At the end ol the feeding experiment, peritoneal macrophages were isolated. The phagocytıc and ınt· racellular Candidacidal indlces were determined. The data were analysed statistically. The results have revealed that allatoxıcosıs depressed both phagocytıc and Candidacidal potential of paritonaat macrophages. PVPP addrtıon pre· vented the anımals from deppressive effects caused by aflatoxins on peritoneal macrophage functıons

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Details

Other ID JA73PH52BS
Journal Section Research
Authors

İlhami Çelik This is me

Ömer Demet This is me

Hasan Hüseyin Dönmez This is me

Halis Oğuz

Murat Boydak This is me

Publication Date March 1, 1996
Published in Issue Year 1996 Volume: 12 Issue: 1

Cite

APA Çelik, İ., Demet, Ö., Dönmez, H. H., Oğuz, H., et al. (1996). Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages lsolated from Chickens Fed with Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed. Eurasian Journal of Veterinary Sciences, 12(1), 145-151.
AMA Çelik İ, Demet Ö, Dönmez HH, Oğuz H, Boydak M. Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages lsolated from Chickens Fed with Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed. Eurasian J Vet Sci. March 1996;12(1):145-151.
Chicago Çelik, İlhami, Ömer Demet, Hasan Hüseyin Dönmez, Halis Oğuz, and Murat Boydak. “Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages Lsolated from Chickens Fed With Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed”. Eurasian Journal of Veterinary Sciences 12, no. 1 (March 1996): 145-51.
EndNote Çelik İ, Demet Ö, Dönmez HH, Oğuz H, Boydak M (March 1, 1996) Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages lsolated from Chickens Fed with Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed. Eurasian Journal of Veterinary Sciences 12 1 145–151.
IEEE İ. Çelik, Ö. Demet, H. H. Dönmez, H. Oğuz, and M. Boydak, “Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages lsolated from Chickens Fed with Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed”, Eurasian J Vet Sci, vol. 12, no. 1, pp. 145–151, 1996.
ISNAD Çelik, İlhami et al. “Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages Lsolated from Chickens Fed With Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed”. Eurasian Journal of Veterinary Sciences 12/1 (March 1996), 145-151.
JAMA Çelik İ, Demet Ö, Dönmez HH, Oğuz H, Boydak M. Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages lsolated from Chickens Fed with Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed. Eurasian J Vet Sci. 1996;12:145–151.
MLA Çelik, İlhami et al. “Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages Lsolated from Chickens Fed With Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed”. Eurasian Journal of Veterinary Sciences, vol. 12, no. 1, 1996, pp. 145-51.
Vancouver Çelik İ, Demet Ö, Dönmez HH, Oğuz H, Boydak M. Determination of Phagocytic and Candidacidal Activities of Peritoneal Macrophages lsolated from Chickens Fed with Aflatoxin and an Aflatoxin Adsorbing Agent, Polyvinylpolypyrrolidone (PVPP) Containing Feed. Eurasian J Vet Sci. 1996;12(1):145-51.