eur res j

The European Research Journal

2149-3189

Prusa Medical Publishing

10.18621/eurj.1245511

Biochemistry and Cell Biology (Other)

Biyokimya ve Hücre Biyolojisi (Diğer)

Immature granulocyte in prediction of the short-term and long-term mortality of patients with acute myocardial infarction

https://orcid.org/0000-0001-5134-1620

Gülten

Sedat

Department of Medical Biochemistry, Kastamonu University, Faculty of Medicine, Kastamonu, Turkey

https://orcid.org/0000-0001-8317-6367

Cihan Çalışgan

Neslihan

Department of Medical Biochemistry, Kastamonu Training and Research Hospital, Kastamonu, Turkey

https://orcid.org/0000-0002-0717-8640

Akyel

Serdar

Department of Cardiology, Kastamonu University, Faculty of Medicine, Kastamonu, Turkey

https://orcid.org/0000-0003-3755-6021

Kukul Güven

Fatma Mutlu

Department of Emergency Medicine, Kastamonu University, Faculty of Medicine, Kastamonu, Turkey

03 04 2023

9 2 338 347 01 31 2023 02 08 2023

2015

The European Research Journal

Objectives: Despite great advances in the treatment of acute myocardial infarction (AMI), it is still the most common cause of death in the world. Therefore, predicting mortality in advance is clinically very important. In this study, we aimed to investigate the role of immature granulocyte (IG) and other hematological markers in predicting short- and long-term mortality in patients with AMI. Methods: Laboratory information system (LIS) data of a tertiary hospital were used in this study. Of the 298 patients who were admitted to the coronary intensive care unit with the diagnosis of myocardial infarction, 258 recovered after treatment and were discharged. 40 of them died. It was determined that 36 of these 258 patients, who were followed up retrospectively, died within 15 months after discharge.Results: The mean age of 298 people who participated in this retrospective study was 73.26 ± 8.6 years, and 53.3% were male. Moderate and high predictive property in receiver operating characteristic (ROC) analysis for short-term mortality, white blood cell (WBC) area under curve (AUC) = 0.802), neutrophil count (AUC = 0.817), IG count (AUC = 0.841), neutrophil/lymphocyte ratio (NLR) (AUC = 0.701), and C-reactive protein (CRP) (AUC = 0.758) tests detected. For long-term mortality, a moderate predictive feature was observed in the age (AUC = 0.712) parameter. Conclusions: IG is a marker that does not require extra cost, provides rapid results and has high predictive value in predicting death in the short term in patients with acute myocardial infarction. It is ineffective in predicting long-term mortality.

Immature granulocyte count acute myocardial infarction mortality inflammation hematological markers

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