eur res j

The European Research Journal

2149-3189

Prusa Medical Publishing

10.18621/eurj.316421

Health Care Administration

Sağlık Kurumları Yönetimi

Importance of preoperative hematological parameters in patients undergoing surgical resection for colorectal cancer

Cayci

Haci Murat

Department of General Surgery, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa Erdogdu

Umut Eren

Department of General Surgery, University of Health Sciences, Bursa Yuksek Ihtisas Training and Research Hospital, Bursa

11 04 2017

3 3 214 219 05 27 2017 07 12 2017

2015

The European Research Journal

Objectives. Colorectal cancer has a high prevalence worldwide, andnew predictive and prognostic factors are needed for its early diagnosis,treatment, and follow-up. In this study, we have investigated the relationshipbetween colorectal cancer and neutrophil to lymphocyte ratio (NLR), mean platelet volume (MPV), and platelet tolymphocyte ratio (PLR) values. Methods. Data from 71 patientsadmitted to our hospital between May 2013 and May 2015, who underwent surgical resectionfor colorectal cancer, and met the criteria of the study, was evaluatedretrospectively. NLR, MPV and PLR data detected in the preoperative period wasnoted. Demographic data, the presence of comorbidity, colonic localization ofthe tumor, colonoscopic findings, and surgical resection type and method werecompared with the data of morbidity and mortality, lymphovascular andperineural invasion, lymph node and distant metastasis and stage of thedisease. Results. No statistical significance was detected betweenpreoperative NLR, MPV, and PLR, demographical data, the presence ofcomorbidity, colonic localization of the tumor, colonoscopic findings, surgicalresection type and method and morbidity, lymph node and distant metastasis,lymphovascular invasion, or stage of the disease. However, a statisticallysignificant relationship was detected between mortality development and NLR andPLR values (p=0.030; p=0.043; respectively). There was also astatistically significant relationship between the presence of perineuralinvasion and PLR (p=0.031). Conclusion.Hematological parameters (NLR, MPV, and PLR) evaluated in preoperative periodin patients who have been applied surgical resection for colorectal cancer mayhelp clinical and pathological staging.

Colorectal cancer surgery mean platelet volume neutrophil to lymphocyte ratio platelet to lymphocyte ratio

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