Primary squamous cell carcinoma of the thyroid: a rare type of thyroid cancer

Year 2017, Volume: 3 Issue: 1, 94 - 98, 04.03.2017

Pinar Sisman Ozlem Saraydaroglu Ahmet Bilgehan Sahin Ozen Oz Gul Soner Cander Canan Ersoy

https://doi.org/10.18621/eurj.294048

Abstract

Primary squamous cell carcinoma of the thyroid is rare but aggressive malignancy. Primary treatment is complete surgical resection of the tumor. If surgical eradication of the tumor is not successful, it has poor prognosis although multimodality treatment. We report a case with multiple thyroid nodules of which fine needle aspiration cytology was suspicious for malignancy. After total thyroidectomy, well differentiated squamous cell carcinoma was observed in histopathological examination. Postoperative investigation ruled out metastasis of the other sites and recurrence has not been observed for 25 months. Early and accurate diagnosis is crucial to achieve complete cure with surgery and long-term survival. 

Keywords

Squamous cell carcinoma, thyroid, cancer

References

• [1] Cho JK, Woo SH, Park J, Kim MJ, Jeong HS. Primary squamous cell carcinomas in the thyroid gland: an individual participant data meta-analysis. Cancer Med 2014;3:1396-403.
• [2] Heitz P, Moser H, Staub JJ. Thyroid cancer: a study of 573 thyroid tumors and 161 autopsy cases observed over a thirty-year period. Cancer 1976;37:2329-37.
• [3] Zimmer PW, Wilson D, Bell N. Primary squamous cell carcinoma of the thyroid gland. Mil Med 2003;168:124-5.
• [4] Oz Gul O, Cander S, Sisman P, Erturk E, Ersoy C. Fifteen-year treatment of metastatic thyroid medullary carcinoma: a case report. Eur Res J 2015;1:160-4.
• [5] Tunio MA, Al Asiri M, Fagih M, Akasha R. Primary squamous cell carcinoma of thyroid: a case report and review of literature. Head Neck Oncol 2012;4:8.
• [6] Syed MI, Stewart M, Syed S, Dahill S, Adams C, McLellan DR, Clark LJ. Squamous cell carcinoma of the thyroid gland: primary or secondary disease? J Laryngol Otol 2011;125:3-9.
• [7] Shrestha M, Sridhara SK, Leo LJ, Coppit GL 3rd, Ehrhardt NM. Primary squamous cell carcinoma of the thyroid gland: a case report and review. Head Neck 2013;35:E299-303.
• [8] Hegerova L, Griebeler ML, Reynolds JP, Henry MR, Gharib H. Metastasis to the thyroid gland: report of a large series from the Mayo Clinic. Am J Clin Oncol 2015;38:338-42.
• [9] Kumar PV, Malekhusseini SA, Talei AR. Primary squamous cell carcinoma of the thyroid diagnosed by fine needle aspiration cytology. A report of two cases. Acta Cytol 1999;43:659-62.
• [10] Lui JT, Khalil MN, Chandarana SP. Primary squamous cell of the thyroid-an abbreviated clinical presentation. J Otolaryngol Head Neck Surg 2014;43:17.