Objectives: To determine the correlation between central corneal thickness (CCT) and central macular thickness (CMT), and fasting plasma glucose levels and HbA1c levels before diabetic macular edema (DME) in type 2 diabetes mellitus (DM) patients without diabetic retinopathy.
Methods: Forty-four eyes of subjects diagnosed with type 2 DM, and 45 healthy control subjects participated in this study. Detailed ophthalmologic examination was performed with all participants. CMT was measured in both groups by Spectral-domain optical coherence tomography. CCT measurements were made with an Echoscan US-500 ultrasonic pachymeter. Blood biochemical tests for glycated hemoglobin (HbA1c) and fasting plasma glucose levels were run on all patients.
Results: The results of the study showed that the mean CCT was significantly thicker in type 2 DM patients 563.84 ± 33.25 μm than in the controls 550.13 ± 28.41 μm (p = 0.039). The mean of CMT was 231.27 ± 37.74 μm in the study group and 225.38 ± 38.33 μm in the control group (p > 0.05). No relationship was found between CCT and CMT and HbA1c level in the study and control groups.
Conclusions: The mean CCT was significantly thicker in type 2 DM patients without diabetic retinopathy than in the controls. The mean CMT is thicker in type 2 DM patients without diabetic retinopathy patients than in the controls, but this difference was not statistically significant. Optical coherence tomography can be a perfect detector for early detection of DME.
|Subjects||Health Care Sciences and Services|
|Journal Section||Original Articles|
Publication Date : October 4, 2018
|EndNote||%0 The European Research Journal Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema %A Kuddusi Teberik , Mehmet Tahir Eski , Murat Kaya %T Associations of glycated hemoglobin (HbA1c) level with central corneal and macular thickness in diabetic patients without macular edema %D 2018 %J The European Research Journal %P -2149-3189 %V 4 %N 4 %R doi: 10.18621/eurj.362263 %U 10.18621/eurj.362263|