Effect of urinary excretion on radiation dose in patients having PET/CT scans

Year 2019, Volume: 5 Issue: 5, 722 - 728, 04.09.2019

Serdar Savaş Gül Mehmet Esen

https://doi.org/10.18621/eurj.410072

Cited By: 2

Abstract

Objectives:
¹⁸Fluorine-fluorodeoxyglucose (¹⁸F-FDG)
positron emission tomography/ computed tomography (PET/CT) is commonly used for
diagnosis, staging and re-staging of cancers and for determining the
effectiveness of treatment. Because of renal, ureteral and urinary involvement
of ¹⁸F-FDG radiopharmaceutical after its injection, patients
subject to radioactivity during its effective half-life. The aim of the present
study was to determine the degree of association between effective dose levels
of patients and bladder emptying of patients having PET/CT scans.

Methods: The present retrospective
study included 108 patients
(43 females and 65 males, average age: 60.9 ± 12.7 years). Effective dose level
as mSv/h was determined from a distance of 1 m in all patients before and after
bladder emptying at the first hour following ¹⁸F-FDG injection.
Radioactivity excretion amounts were compared based on gender, age, body mass
index, fasting blood sugar level and clinical diagnosis.

Results: Amount of radioactivity decreased by 22.75% ± 14.77%
after bladder emptying. No association was found between urinary excretion
level and age, gender, fasting blood sugar and body mass index (p > 0.05).

Conclusions: Active
emptying of bladder in patients having PET/CT scans where ¹⁸F-FDG
radiopharmaceutical is involved is an effective method for the radiation safety
of both health workers and patients. 

Keywords

18Fluorine-fluorodeoxyglucose, positron emission tomography, computed tomography, urinary excretion, effective dose

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