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            <front>

                <journal-meta>
                                                                <journal-id>farabi med j</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Farabi Tıp Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2979-9821</issn>
                                                                                            <publisher>
                    <publisher-name>Karadeniz Technical University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id pub-id-type="doi">10.59518/farabimedj.1775226</article-id>
                                                                <article-categories>
                                            <subj-group  xml:lang="en">
                                                            <subject>Metabolic Medicine</subject>
                                                    </subj-group>
                                            <subj-group  xml:lang="tr">
                                                            <subject>Metabolik Tıp</subject>
                                                    </subj-group>
                                    </article-categories>
                                                                                                                                                        <title-group>
                                                                                                                        <article-title>Evaluation of Serum Adropin, Irisin, and Preptin Levels in Individuals with Benign Prostatic Hyperplasia and Prostate Cancer</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="tr">
                                    <trans-title>Benign Prostat Hiperplazisi ve Prostat Kanserli Bireylerde Serum Adropin, İrisin ve Preptin Düzeylerinin Değerlendirilmesi</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-7503-2416</contrib-id>
                                                                <name>
                                    <surname>Bodur</surname>
                                    <given-names>Solmaz</given-names>
                                </name>
                                                                    <aff>ADIYAMAN ÜNİVERSİTESİ, TIP FAKÜLTESİ</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-0208-8929</contrib-id>
                                                                <name>
                                    <surname>İlhan</surname>
                                    <given-names>Nevin</given-names>
                                </name>
                                                                    <aff>FIRAT UNIVERSITY, SCHOOL OF MEDICINE</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0003-2736-2573</contrib-id>
                                                                <name>
                                    <surname>Yildiz</surname>
                                    <given-names>Furkan</given-names>
                                </name>
                                                                    <aff>İzmir City Hospital Department of Urology and Andrology,</aff>
                                                            </contrib>
                                                    <contrib contrib-type="author">
                                                                    <contrib-id contrib-id-type="orcid">
                                        https://orcid.org/0000-0002-5507-7983</contrib-id>
                                                                <name>
                                    <surname>Berk</surname>
                                    <given-names>Buket</given-names>
                                </name>
                                                                    <aff>FIRAT UNIVERSITY, SCHOOL OF MEDICINE</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20251230">
                    <day>12</day>
                    <month>30</month>
                    <year>2025</year>
                </pub-date>
                                        <volume>4</volume>
                                        <issue>4</issue>
                                        <fpage>139</fpage>
                                        <lpage>144</lpage>
                        
                        <history>
                                    <date date-type="received" iso-8601-date="20250831">
                        <day>08</day>
                        <month>31</month>
                        <year>2025</year>
                    </date>
                                                    <date date-type="accepted" iso-8601-date="20251116">
                        <day>11</day>
                        <month>16</month>
                        <year>2025</year>
                    </date>
                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 2022, Farabi Tıp Dergisi</copyright-statement>
                    <copyright-year>2022</copyright-year>
                    <copyright-holder>Farabi Tıp Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are common urological conditions among aging men, characterized by benign enlargement and malignant progression of the prostate gland, respectively. This study was designed to answer the question of whether adropin, irisin, and preptin serum levels have an impact on the development of prostate disease in a total of 90 participants, including BPH (n=30), localized PCa (n=30), and healthy controls (n=30). The serum concentrations of these peptides were determined using enzyme-linked immunosorbent assay (ELISA). According to the findings, adropin and irisin levels were significantly lower in the BPH and PCa groups compared to the control group (p</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="tr">
                            <p>Benign prostat hiperplazisi (BPH) ve prostat kanseri (PCa), yaşlanan erkekler arasında sık görülen ve sırasıyla prostat bezinin iyi huylu büyümesi ve kötü huylu gelişimi ile karakterize olan ürolojik durumlardır. Bu çalışma, BPH (n=30), lokalize PCa (n=30) ve sağlıklı kontrol grubundan (n=30) oluşan 90 katılımcıda adropin, irisin ve preptin serum düzeylerinin prostat hastalığı gelişiminde bir etkisi var mıdır sorusuna yanıt bulmak amacıyla tasarlanmıştır. Çalışmada bu peptidlerin serum konsantrasyonları, enzim bağlı immünosorbent test yöntemiyle ölçülmüştür. Elde edilen bulgulara göre BPH ve PCa gruplarında kontrol grubuna kıyasla adropin ve irisin düzeylerinde anlamlı bir azalma olduğu tespit edilmiştir (p</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Adropin</kwd>
                                                    <kwd>  BPH</kwd>
                                                    <kwd>  Irisin</kwd>
                                                    <kwd>  Preptin</kwd>
                                                    <kwd>  Prostate health</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="tr">
                                                    <kwd>Adropin</kwd>
                                                    <kwd>  BPH</kwd>
                                                    <kwd>  İrisin</kwd>
                                                    <kwd>  Preptin</kwd>
                                                    <kwd>  Prostat sağlığı</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
    <back>
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    </article>
