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Year 2020, Volume 1 , Issue 1, Pages 22 - 27 2020-09-30

Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa

Barış GÖKALSIN [1] , Didem BERBER [2] , Jae-seoun HUR [3] , Cenk SESAL [4]

Abstract

Communication among bacterial cells through quorum sensing (QS) system in Pseudomonas aeruginosa is responsible for antibiotic resistant infections in hospitals. This bacterium can regulate its virulence gene expressions through its QS systems. It is now known that inhibiting QS can leave bacteria vulnerable. Therefore, it is necessary to determine natural sources to obtain potential quorum sensing inhibitors. This study aims to investigate the QS inhibitor (QSI) bioactivity of the culture extracts obtained from lichen-forming fungi (LFF) of five Cetrelia species against P. aeruginosa. Extracts were applied to monitor strains and all samples have shown varying amounts of QS inhibition activity. Our study demonstrates that LFF cultures can be utilized to produce QSI compounds instead of collecting slow growing natural lichen thalli. We believe that this research will cast a new light on identification and isolation of active compounds from the extracts and assessment of their compatibility for future drug research.

Keywords

quorum sensing, Pseudomonas aeruginosa, secondary metabolites, lichen forming fungi

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Details

Primary Language en
Subjects Biology
Journal Section Research Articles
Authors

Orcid: 0000-0001-5060-6834
Author: Barış GÖKALSIN
Institution: MARMARA ÜNİVERSİTESİ
Country: Turkey

Orcid: 0000-0001-5813-160X
Author: Didem BERBER
Institution: MALTEPE ÜNİVERSİTESİ
Country: Turkey

Orcid: 0000-0001-8547-7075
Author: Jae-seoun HUR
Institution: Sunchon National University
Country: South Korea

Orcid: 0000-0002-0737-0122
Author: Cenk SESAL (Primary Author)
Institution: MARMARA ÜNİVERSİTESİ
Country: Turkey
Supporting Institution TÜBİTAK
Project Number 218S752
Thanks This study was funded by The Scientific and Technological Research Council of Turkey (TUBITAK) [Bilateral Collaboration Project No: 218S752].
Dates

Application Date : September 4, 2020
Acceptance Date : September 23, 2020
Publication Date : September 30, 2020

Cite

Bibtex @research article { flsrt784276, journal = {Frontiers in Life Sciences and Related Technologies}, issn = {}, eissn = {2718-062X}, address = {Marmara University, Faculty of Science \& Arts, Department of Biology, 34722, Goztepe, Istanbul, Turkey}, publisher = {İbrahim İlker ÖZYİĞİT}, year = {2020}, volume = {1}, pages = {22 - 27}, doi = {}, title = {Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa}, key = {cite}, author = {Gökalsın, Barış and Berber, Didem and Hur, Jae-seoun and Sesal, Cenk} }
APA Gökalsın, B , Berber, D , Hur, J , Sesal, C . (2020). Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa . Frontiers in Life Sciences and Related Technologies , 1 (1) , 22-27 . Retrieved from https://dergipark.org.tr/en/pub/flsrt/issue/56859/784276
MLA Gökalsın, B , Berber, D , Hur, J , Sesal, C . "Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa" . Frontiers in Life Sciences and Related Technologies 1 (2020 ): 22-27 <https://dergipark.org.tr/en/pub/flsrt/issue/56859/784276>
Chicago Gökalsın, B , Berber, D , Hur, J , Sesal, C . "Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa". Frontiers in Life Sciences and Related Technologies 1 (2020 ): 22-27
RIS TY - JOUR T1 - Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa AU - Barış Gökalsın , Didem Berber , Jae-seoun Hur , Cenk Sesal Y1 - 2020 PY - 2020 N1 - DO - T2 - Frontiers in Life Sciences and Related Technologies JF - Journal JO - JOR SP - 22 EP - 27 VL - 1 IS - 1 SN - -2718-062X M3 - UR - Y2 - 2020 ER -
EndNote %0 Frontiers in Life Sciences and Related Technologies Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa %A Barış Gökalsın , Didem Berber , Jae-seoun Hur , Cenk Sesal %T Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa %D 2020 %J Frontiers in Life Sciences and Related Technologies %P -2718-062X %V 1 %N 1 %R %U
ISNAD Gökalsın, Barış , Berber, Didem , Hur, Jae-seoun , Sesal, Cenk . "Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa". Frontiers in Life Sciences and Related Technologies 1 / 1 (September 2020): 22-27 .
AMA Gökalsın B , Berber D , Hur J , Sesal C . Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa. Front Life Sci RT. 2020; 1(1): 22-27.
Vancouver Gökalsın B , Berber D , Hur J , Sesal C . Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa. Frontiers in Life Sciences and Related Technologies. 2020; 1(1): 22-27.
IEEE B. Gökalsın , D. Berber , J. Hur and C. Sesal , "Quorum sensing inhibition properties of lichen forming fungi extracts from Cetrelia species against Pseudomonas aeruginosa", Frontiers in Life Sciences and Related Technologies, vol. 1, no. 1, pp. 22-27, Sep. 2020
Authors of the Article
Barış GÖKALSIN [1]
Didem BERBER [2]
Jae-seoun HUR [3]
Cenk SESAL [4]
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