Kliniğimizde radyoaktif iyot tedavisi alan diferansiye tiroid karsinomlu hastaların demografik analizi

Umut Elboğa; Neşe Doğan; Ebuzer Kalender; Y. Zeki Çelen; Mustafa Yılmaz; Hasan Deniz Demir; Suna Erkılıç; Hüseyin Karaoğlan

Demographical analysis of the patients received radioiodine therapy for the differentiated thyroid carcinoma in our clinic

Year 2012, Volume: 18 Issue: 1, 27 - 30, 01.02.2012

Umut Elboğa Neşe Doğan Ebuzer Kalender Y. Zeki Çelen Mustafa Yılmaz Hasan Deniz Demir Suna Erkılıç Hüseyin Karaoğlan

Abstract

Our aim was to determine the correlation of a well differentiated thyroid carcinoma with gender and age. Our retrospective study evaluated 736 patients received ablation therapy between 2008 and 2011, consisted of 600 females and 136 males. The rate of female to male was 4,4/1 in differentiated thyroid carcinoma. Our patients aged between 14 to 89 during the diagnosis with a mean age of 46,9±12,8. The mean diagnosis age was 47,2±13,1 for females, while 46,1±13,3 for males. Papillary carcinoma was found as the most common type of tumor with 87% and the second common type was follicular carcinoma with 11%. In all type of thyroid cancers female patients were more than males. There was not any statistically significant difference between the mean diagnosis age for follicular thyroid cancer and for papillary thyroid cancer.

Keywords

Thyroid Neoplasms, Retrospective Studies, Demography, Radioisotopes

References

1. Jameson JL, Weetman AP. Disorders of the thyroid gland. In: Kasper DL, Fauci AS, Longo DL, Braunwald E, Hauser SL, Jameson JL.: Harrison's Principles of Internal Medicine, 16th Edition, New York: The McGraw Hill Companies, 2005; 320:2014-212.
2. Carling T, Udelsman R. Thyroid tumors. In: DeVita VT, Hellman S, Rosenberg SA., Cancer: Principles and Practice of Oncology. 7th Edition, Philadelphia: Lippincott Williams & Wilkins, 2005; 34:1502-19.
3. Mazzaferri EL, Kloos RT. Current approaches to primary therapy for papillary and follicular thyroid cancer. J Clin Endocrinol Metab 2001;86(4):1447-63.
4. Merhy J, Driscoll HK, Leidy JW, Chertow BS. Increasing incidence and characteristics of differentiated thyroid cancer in Huntington, West Virginia. Thyroid 2001;11(11):1063-9.
5. Starnes HF, Brooks DC, Pinkus GS, Brooks JR. Surgery for thyroid carcinoma. Cancer 1985;55(6):1376-81.
6. Burgess JR. Temporal trends for thyroid carcinoma in Australia: an increasing incidence of papillary thyroid carcinoma (1982- 1997). Thyroid 2002;12(2):141-9.
7. Muro-Cacho CA, Ku NN. Tumors of the thyroid gland: histologic and cytologic features-part 1. Cancer Control 2000;7(3):276-87.
8. Kumar V. Diseases of the endocrine system. In: Kumar V, Cotran R, Robbins SL., Basic Pathology, 5th edition, WB Saunders, Philadelphia, Pennsylvania, 1992; 20:643-80.
9. Franssila KO, Ackerman LV, Brown CL, Hedinger CE. Follicular carcinoma. Semin Diagn Pathol 1985;2(2):101-22.
10. Leung AK, Chow SM, Law SC. Clinical features and outcome of the tall cell variant of papillary thyroid carcinoma. Laryngoscope 2008;118(1):32-8.
11. Lin JD, Chao TC, Hsueh C. Follicular thyroid carcinomas with lung metastases: a 23-year retrospective study. Endocr J 2004;51(2):219-25.
12. Clark JR, Lai P, Hall F, Borglund A, Eski S, Freeman JL. Variables predicting distant metastases in thyroid cancer. Laryngoscope 2005;115(4):661-7.

Kliniğimizde radyoaktif iyot tedavisi alan diferansiye tiroid karsinomlu hastaların demografik analizi

Year 2012, Volume: 18 Issue: 1, 27 - 30, 01.02.2012

Umut Elboğa Neşe Doğan Ebuzer Kalender Y. Zeki Çelen Mustafa Yılmaz Hasan Deniz Demir Suna Erkılıç Hüseyin Karaoğlan

Abstract

Çalışmamızın amacı, iyi diferansiye tiroid karsinomunun yaş ve cinsiyetle ilişkisini saptamak, hastalığın mortalite ve morbiditesini etkileyen risk faktörlerini ve bunların birbirleriyle ilişkilerini ortaya koymaktır. 2008-2011 yılları arasında ablasyon tedavisi alan iyi diferansiye tiroid kanserli 600'ü kadın, 136'sı erkek toplam 736 hasta retrospektif çalışmada değerlendirilmiştir. Kadın/erkek oranı tüm diferansiye tiroid karsinomunda 4,4/1 olarak bulunmuştur. Hastalarımızın tanı yaşları 14-89 yaş arasında dağılım göstermekte olup ortalama tanı yaşı 46,9±12,8 yıldır. Ortalama tanı yaşı bayan hastalarda 47,2±13,1 iken erkek hastalarda 46,1±13,3 olarak tespit edilmiştir. Tümör tipleri içinde %87 ile en yüksek oranda papiller karsinom, ikinci sıklıkta %11 ile foliküler karsinom tespit edilmiştir. Tiroid kanseri tüm tiplerinde kadın hasta sayısı erkek hasta sayısından yüksek olarak saptanmıştır. Papiller veya folliküler histolojik tipte tiroid karsinomu ile tanı yaşı arasında istatistiksel olarak anlamlı bir ilişki bulunmamıştır.

Keywords

Tiroid neoplazmları, Geriyedönük çalışma, Demografi, Radyoizotoplar

References

1. Jameson JL, Weetman AP. Disorders of the thyroid gland. In: Kasper DL, Fauci AS, Longo DL, Braunwald E, Hauser SL, Jameson JL.: Harrison's Principles of Internal Medicine, 16th Edition, New York: The McGraw Hill Companies, 2005; 320:2014-212.
2. Carling T, Udelsman R. Thyroid tumors. In: DeVita VT, Hellman S, Rosenberg SA., Cancer: Principles and Practice of Oncology. 7th Edition, Philadelphia: Lippincott Williams & Wilkins, 2005; 34:1502-19.
3. Mazzaferri EL, Kloos RT. Current approaches to primary therapy for papillary and follicular thyroid cancer. J Clin Endocrinol Metab 2001;86(4):1447-63.
4. Merhy J, Driscoll HK, Leidy JW, Chertow BS. Increasing incidence and characteristics of differentiated thyroid cancer in Huntington, West Virginia. Thyroid 2001;11(11):1063-9.
5. Starnes HF, Brooks DC, Pinkus GS, Brooks JR. Surgery for thyroid carcinoma. Cancer 1985;55(6):1376-81.
6. Burgess JR. Temporal trends for thyroid carcinoma in Australia: an increasing incidence of papillary thyroid carcinoma (1982- 1997). Thyroid 2002;12(2):141-9.
7. Muro-Cacho CA, Ku NN. Tumors of the thyroid gland: histologic and cytologic features-part 1. Cancer Control 2000;7(3):276-87.
8. Kumar V. Diseases of the endocrine system. In: Kumar V, Cotran R, Robbins SL., Basic Pathology, 5th edition, WB Saunders, Philadelphia, Pennsylvania, 1992; 20:643-80.
9. Franssila KO, Ackerman LV, Brown CL, Hedinger CE. Follicular carcinoma. Semin Diagn Pathol 1985;2(2):101-22.
10. Leung AK, Chow SM, Law SC. Clinical features and outcome of the tall cell variant of papillary thyroid carcinoma. Laryngoscope 2008;118(1):32-8.
11. Lin JD, Chao TC, Hsueh C. Follicular thyroid carcinomas with lung metastases: a 23-year retrospective study. Endocr J 2004;51(2):219-25.
12. Clark JR, Lai P, Hall F, Borglund A, Eski S, Freeman JL. Variables predicting distant metastases in thyroid cancer. Laryngoscope 2005;115(4):661-7.

There are 12 citations in total.

Details

Primary Language	Turkish
Journal Section	Articles
Authors	Umut Elboğa This is me Neşe Doğan This is me Ebuzer Kalender This is me Y. Zeki Çelen This is me Mustafa Yılmaz This is me Hasan Deniz Demir This is me Suna Erkılıç This is me Hüseyin Karaoğlan This is me
Publication Date	February 1, 2012
Published in Issue	Year 2012 Volume: 18 Issue: 1

Cite

APA	Elboğa, U., Doğan, N., Kalender, E., Çelen, Y. Z., et al. (2012). Kliniğimizde radyoaktif iyot tedavisi alan diferansiye tiroid karsinomlu hastaların demografik analizi. Gaziantep Medical Journal, 18(1), 27-30.
AMA	Elboğa U, Doğan N, Kalender E, Çelen YZ, Yılmaz M, Demir HD, Erkılıç S, Karaoğlan H. Kliniğimizde radyoaktif iyot tedavisi alan diferansiye tiroid karsinomlu hastaların demografik analizi. Gaziantep Medical Journal. February 2012;18(1):27-30.
Chicago	Elboğa, Umut, Neşe Doğan, Ebuzer Kalender, Y. Zeki Çelen, Mustafa Yılmaz, Hasan Deniz Demir, Suna Erkılıç, and Hüseyin Karaoğlan. “Kliniğimizde Radyoaktif Iyot Tedavisi Alan Diferansiye Tiroid Karsinomlu hastaların Demografik Analizi”. Gaziantep Medical Journal 18, no. 1 (February 2012): 27-30.
EndNote	Elboğa U, Doğan N, Kalender E, Çelen YZ, Yılmaz M, Demir HD, Erkılıç S, Karaoğlan H (February 1, 2012) Kliniğimizde radyoaktif iyot tedavisi alan diferansiye tiroid karsinomlu hastaların demografik analizi. Gaziantep Medical Journal 18 1 27–30.
IEEE	U. Elboğa, N. Doğan, E. Kalender, Y. Z. Çelen, M. Yılmaz, H. D. Demir, S. Erkılıç, and H. Karaoğlan, “Kliniğimizde radyoaktif iyot tedavisi alan diferansiye tiroid karsinomlu hastaların demografik analizi”, Gaziantep Medical Journal, vol. 18, no. 1, pp. 27–30, 2012.
ISNAD	Elboğa, Umut et al. “Kliniğimizde Radyoaktif Iyot Tedavisi Alan Diferansiye Tiroid Karsinomlu hastaların Demografik Analizi”. Gaziantep Medical Journal 18/1 (February 2012), 27-30.
JAMA	Elboğa U, Doğan N, Kalender E, Çelen YZ, Yılmaz M, Demir HD, Erkılıç S, Karaoğlan H. Kliniğimizde radyoaktif iyot tedavisi alan diferansiye tiroid karsinomlu hastaların demografik analizi. Gaziantep Medical Journal. 2012;18:27–30.
MLA	Elboğa, Umut et al. “Kliniğimizde Radyoaktif Iyot Tedavisi Alan Diferansiye Tiroid Karsinomlu hastaların Demografik Analizi”. Gaziantep Medical Journal, vol. 18, no. 1, 2012, pp. 27-30.
Vancouver	Elboğa U, Doğan N, Kalender E, Çelen YZ, Yılmaz M, Demir HD, Erkılıç S, Karaoğlan H. Kliniğimizde radyoaktif iyot tedavisi alan diferansiye tiroid karsinomlu hastaların demografik analizi. Gaziantep Medical Journal. 2012;18(1):27-30.