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Pyuria in hip fracture and coxarthrosis

Year 2012, Volume: 18 Issue: 2, 66 - 71, 01.03.2012

Abstract

Accompanying systemic pathologies and other risk factors can be found in the most elderly patients who treated for hip fracture or coxarthrosis. All of these can cause urinary tract infection and colonization of bacteria in the urinary tract. Pyuria and urinary tract infection could pose a risk after the orthopedic implant surgery and is a frightening complication of surgical site wound infection. In this study, we investigated that the relationship between preoperative pyuria and postoperative surgical site infections, affect the risk factors in patients who underwent hip implant surgery or hip arthroplasty because of hip fracture or coxarthrosis. The period between 1994-2008, 563 patients with at least one year follow-up records were reviewed retrospectively. Working group was comprised of 38 cases detected preoperative pyuria (urine microscopy >10 white blood cell/field), the 62 patients that were randomly selected among the rest of 525 patients constituted the control group. Groups of age, gender, etiology, fever, hemoglobin, sedimentation rate, Creactive protein, white blood cell, albumin, preoperative period of time, diabetes, co-morbidities, urine culture in terms of reproductive and post-operative surgical site infection were compared. In the study group, blood albumin level was lower than the control group. In addition, the preoperative period and postoperative surgical site infection, urine culture positivity were higher than the control group. There was statistical difference between groups (p0.05). The results of this study, preoperative length of time, culture positivity and low level of albumin show significant risk factors for postoperative surgical site infection. In addition to the preoperative symptomatic urinary tract infection seems associated with surgical wound infection after surgery. Orthopedic surgery can be delayed until the preoperative treatment of symptomatic urinary tract infection, however we think that there is no correlation between preoperative asymptomatic pyuria and postoperative surgical site infection. And it is not necessary to delay orthopedic surgery in patients with asymptomatic pyuria.

References

  • 1. Uzunköy A. Cerrahi alan enfeksiyonları: risk faktörleri ve önleme yöntemleri. Ulus Travma Derg 2005;11(4):269-81.
  • 2. Bozic KJ, Ries MD. The impact of infection after total hip arthroplasty on hospital and surgeon resource utilization. J Bone Joint Surg Am 2005;87(8):1746-51.
  • 3. Koulouvaris P, Sculco P, Finerty E, Sculco T, Sharrock NE. Relationship between perioperative urinary tract infection and deep infection after joint arthroplasty. Clin Orthop Relat Res 2009;467(7):1859-67.
  • 4. Rajamanickam A, Noor S, Usmani A. Should an asymptomatic patient with an abnormal urinalysis (bacteriuria or pyuria) be treated with antibiotics prior to major joint replacement surgery? Cleve Clin J Med 2007;74(Suppl 1):S17-8.
  • 5. Oztürk I, Toker S, Ertürer E, Aksoy B, Seçkin F. Kalça kırığı nedeniyle ameliyat edilen 65 yaş üstü hastalarda mortaliteye etki eden risk faktörlerinin değerlendirilmesi. Acta Orthop Traumatol Turc 2008;42(1):16-21.
  • 6. Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A, Hooton TM. Infectious Diseases Society of America; American Society of Nephrology; American Geriatric Society. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005:40(5);643-54.
  • 7. Acar A, Öncül O. Cerrahi Alan infeksiyonları. Klimik Dergisi 2007;20(2):35-46.
  • 8. Kaçmaz B, Sultan N. Bakteriyüri ve piyüri saptanmasında kullanılan iki yöntemin değerlendirilmesi. İnfeksiyon Dergisi 2003;17(3):337-40.
  • 9. Öztürk U, İmamoğlu MA. Komplike olmayan üriner enfeksiyonlarda antibiyotik uygulamaları. Turk Urol Sem 2010;1(8):226-31.
  • 10. Jämsen E, Furnes O, Engesæter LB, Konttinen YT, Odgaard A, Stefánsdóttir A et al. Prevention of deep infection in joint replacement surgery. Acta Orthop 2010;81(6):660-6.
  • 11. Stéphan F, Sax H, Wachsmuth M, Hoffmeyer P, Clergue F, Pittet D. Reduction of urinary tract infection and antibiotic use after surgery: a controlled, prospective, before-after intervention study. Clin Infect Dis 2006;42(11):1544-51.
  • 12. Kandemir Ö, Milcan A, Şahin E, Çolak M, Kaya A. Ortopedik endoprotez ve açık redüksiyon-internal tespit operasyonları sonrası infeksiyonlar. Klimik Dergisi 2003;16(1):34-7.
  • 13. Berbari EF, Hanssen AD, Duffy MC, Steckelberg JM, Ilstrup DM, Harmsen WS et al. Risk factors for prosthetic joint infection: case-control study. Clin Infect Dis 1998;27(5):1247- 54.
  • 14. Rao N, Soxman GL. Prosthetic joint infections in the elderly. Operative Techniques in Orthopedics 2002;12(2):131-8.
  • 15. Başkonuş İ, Borazan E, Maralcan G, Aybastı N, Gökalp A, Balık AA. The effects of perioperative total parenteral nutrition on postoperative mortality and morbidity. Gaziantep Med J 2011;17(3):141-6.
  • 16. Simunovic N, Devereaux P, Bhandari M. Surgery for hip fractures: Does surgical delay affect outcomes? Indian J Orthop 2011;45(1):27-32.
  • 17. Dieter RS. Sterile pyuria: a differential diagnosis. Compr Ther 2000:26(3);150-2.
  • 18. Anderson CF, Wochos DN. The utility of serum albumin values in the nutritional assessment of hospitalized patients. Mayo Clin Proc 1982;57(3):181-4.
  • 19. Nielubowicz GR, Mobley HL. Host-pathogen interactions in urinary tract infection. Nat Rev Urol 2010:7(8);430-41.
  • 20. Sia IG, Berbari EF, Karchmer AW. Prosthetic joint infections. Infect Dis Clin North Am 2005;19(4):885-914.
  • 21. Widmer AF. New developments in diagnosis and treatment of infection in orthopedic implants. Clin Infect Dis 2001;33(Suppl 2):S94-106.
  • 22. Brown WJ. Microbiology of the infected total joint arthroplasty. Semin Arthroplasty 1994;5(3):107-13.
  • 23. Bulut O, Öztemür Z. Ortopedik travmatolojik cerrahide antibiyotik proflaksisi. Cumhuriyet Üniversitesi Tıp Fakültesi Dergisi 2002;24(2):97-100.
  • 24. Tai CC, Nirvani AA, Holmes A, Hughes SP. Methicillinresistant Staphylococcus aureus in orthopaedic surgery. Int Orthop 2004;28(1):32-5.
  • 25. Akhan SÇ, Özsüt H, Eraksoy H, Hamzaoğlu A, Dilmener M, Çalangu S. Ortopedik yabancı cisim ve protez infeksiyonları. Klimik Dergisi 2000;13(3):88-90.
  • 26. David TS, Vrahas MS. Perioperative lower urinary tract infections and deep sepsis in patients undergoing total joint arthroplasty. J Am Acad Orthop Surg 2000;8(1):66-74.
  • 27. Glynn MK, Sheehan JM. The significance of asymptomatic bacteriuria in patients undergoing hip/knee arthroplasty. Clin Orthop Relat Res 1984;185:151-4.
  • 28. Ahnfelt L, Herberts P, Malchau H, Andersson GB. Prognosis of total hip replacement. A Swedish multicenter study of 4664 revisions. Acta Orthop Scand 1990;238(Suppl):l-26.
  • 29. Maderazo EG, Judson S, Pasternak H. Late infections of total joint prostheses: a review and recommendations for prevention. Clin Orthop Relat Res 1988;229:131-42.
  • 30. Saleh K, Olson M, Resig S, Bershadsky B, Kuskowski M, Gioe T, et al. Predictors of wound infection in hip and knee joint replacement: results from a 20 year surveillance program. J Orthop Res 2002;20(3):506-15.
  • 31. Wymenga AB, van Horn JR, Theeuwes A, Muytjens HL, Slooff TJ. Perioperative factors associated with septic arthritis after arthroplasty. Prospective multicenter study of 362 knee and 2,651 hip operations. Acta Orthop Scand 1992;63(6):665-71.
  • 32. Irvine R, Johnson BL Jr, Amstutz HC. The relationship of genitourinary tract procedures and deep sepsis after total hip replacements. Surg Gynecol Obstet 1974;139(5):701-6.
  • 33. Ritter MA, Fechtman RW. Urinary tract sequelae: possible influence on joint infections following total joint replacement. Orthopedics 1987;10(3):467-9.

Kalça kırığı ve koksartrozda piyüri

Year 2012, Volume: 18 Issue: 2, 66 - 71, 01.03.2012

Abstract

Kalça kırığı ya da koksartroz nedeniyle tedavi edilen yaşlı olguların çoğunda eşlik eden sistemik patolojiler ve diğer risk faktörleri bulunabilir. Bütün bunlar idrar yolarında bakteri kolonizasyonuna ve idrar yolu enfeksiyonuna neden olabilir. Piyüri ve idrar yolları enfeksiyonu ortopedik implant cerrahisi sonrası korkutucu bir komplikasyon olan cerrahi alan yara enfeksiyonu için risk oluşturabilir. Bu çalışmada kalça kırığı ya da koksartroz nedeniyle kalça implant cerrahisi veya artroplastisi yapılan hastalarda ameliyat öncesi piyüri ile ameliyat sonrası cerrahi alan enfeksiyonu arasındaki ilişki ve etki eden risk faktörleri araştırıldı. 1994-2008 yılları arasındaki dönemde en az bir yıllık takip kayıtları olan 563 olgu retrospektif olarak incelendi. Ameliyat öncesi piyüri (idrar mikroskopisinde >10 lökosit/saha) saptanan 38 olgu çalışma grubunu geri kalan 525 olgudan rastgele seçilen 62 olgu ise kontrol grubunu oluşturdu. Gruplar; yaş, cinsiyet, etyoloji, ateş, hemoglobin, sedimantasyon, C-reaktif protein, beyaz küre, albümin, ameliyat öncesi süre, diabet, eşlik eden hastalıklar, idrar kültüründe üreme ve ameliyat sonrası cerrahi alan enfeksiyonu açısından karşılaştırıldı. Çalışma grubunda, kan albümin seviyesi kontrol grubundan daha düşüktü. Ayrıca ameliyat öncesi süre, idrar kültüründe üreme olması ve ameliyat sonrası cerrahi alan enfeksiyonu ise kontrol grubundan daha fazlaydı. Gruplar arasında istatistiksel anlamlı fark vardı (p0.05). Bu çalışmanın sonuçları, ameliyat öncesi sürenin uzun olması, kan albümin seviyesi düşüklüğü ve idrar kültüründe üreme olmasının ameliyat sonrası cerrahi alan enfeksiyonu için önemli risk faktörleri olduğunu göstermektedir. Ek olarak ameliyat öncesi semptomatik idrar yolu enfeksiyonu ameliyat sonrası cerrahi alan yara enfeksiyonu ile ilişkili gözükmektedir. Ameliyat öncesi semptomatik idrar yolu enfeksiyonu tedavi edilinceye kadar ortopedik cerrahi ertelenebilir. Ancak asemptomatik piyüri ile ameliyat sonrası cerrahi alan enfeksiyonu arasında bir ilişki olmadığını ve bu olgularda ortopedik cerrahinin ertelenmesinin gerekmediğini düşünüyoruz.

References

  • 1. Uzunköy A. Cerrahi alan enfeksiyonları: risk faktörleri ve önleme yöntemleri. Ulus Travma Derg 2005;11(4):269-81.
  • 2. Bozic KJ, Ries MD. The impact of infection after total hip arthroplasty on hospital and surgeon resource utilization. J Bone Joint Surg Am 2005;87(8):1746-51.
  • 3. Koulouvaris P, Sculco P, Finerty E, Sculco T, Sharrock NE. Relationship between perioperative urinary tract infection and deep infection after joint arthroplasty. Clin Orthop Relat Res 2009;467(7):1859-67.
  • 4. Rajamanickam A, Noor S, Usmani A. Should an asymptomatic patient with an abnormal urinalysis (bacteriuria or pyuria) be treated with antibiotics prior to major joint replacement surgery? Cleve Clin J Med 2007;74(Suppl 1):S17-8.
  • 5. Oztürk I, Toker S, Ertürer E, Aksoy B, Seçkin F. Kalça kırığı nedeniyle ameliyat edilen 65 yaş üstü hastalarda mortaliteye etki eden risk faktörlerinin değerlendirilmesi. Acta Orthop Traumatol Turc 2008;42(1):16-21.
  • 6. Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A, Hooton TM. Infectious Diseases Society of America; American Society of Nephrology; American Geriatric Society. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005:40(5);643-54.
  • 7. Acar A, Öncül O. Cerrahi Alan infeksiyonları. Klimik Dergisi 2007;20(2):35-46.
  • 8. Kaçmaz B, Sultan N. Bakteriyüri ve piyüri saptanmasında kullanılan iki yöntemin değerlendirilmesi. İnfeksiyon Dergisi 2003;17(3):337-40.
  • 9. Öztürk U, İmamoğlu MA. Komplike olmayan üriner enfeksiyonlarda antibiyotik uygulamaları. Turk Urol Sem 2010;1(8):226-31.
  • 10. Jämsen E, Furnes O, Engesæter LB, Konttinen YT, Odgaard A, Stefánsdóttir A et al. Prevention of deep infection in joint replacement surgery. Acta Orthop 2010;81(6):660-6.
  • 11. Stéphan F, Sax H, Wachsmuth M, Hoffmeyer P, Clergue F, Pittet D. Reduction of urinary tract infection and antibiotic use after surgery: a controlled, prospective, before-after intervention study. Clin Infect Dis 2006;42(11):1544-51.
  • 12. Kandemir Ö, Milcan A, Şahin E, Çolak M, Kaya A. Ortopedik endoprotez ve açık redüksiyon-internal tespit operasyonları sonrası infeksiyonlar. Klimik Dergisi 2003;16(1):34-7.
  • 13. Berbari EF, Hanssen AD, Duffy MC, Steckelberg JM, Ilstrup DM, Harmsen WS et al. Risk factors for prosthetic joint infection: case-control study. Clin Infect Dis 1998;27(5):1247- 54.
  • 14. Rao N, Soxman GL. Prosthetic joint infections in the elderly. Operative Techniques in Orthopedics 2002;12(2):131-8.
  • 15. Başkonuş İ, Borazan E, Maralcan G, Aybastı N, Gökalp A, Balık AA. The effects of perioperative total parenteral nutrition on postoperative mortality and morbidity. Gaziantep Med J 2011;17(3):141-6.
  • 16. Simunovic N, Devereaux P, Bhandari M. Surgery for hip fractures: Does surgical delay affect outcomes? Indian J Orthop 2011;45(1):27-32.
  • 17. Dieter RS. Sterile pyuria: a differential diagnosis. Compr Ther 2000:26(3);150-2.
  • 18. Anderson CF, Wochos DN. The utility of serum albumin values in the nutritional assessment of hospitalized patients. Mayo Clin Proc 1982;57(3):181-4.
  • 19. Nielubowicz GR, Mobley HL. Host-pathogen interactions in urinary tract infection. Nat Rev Urol 2010:7(8);430-41.
  • 20. Sia IG, Berbari EF, Karchmer AW. Prosthetic joint infections. Infect Dis Clin North Am 2005;19(4):885-914.
  • 21. Widmer AF. New developments in diagnosis and treatment of infection in orthopedic implants. Clin Infect Dis 2001;33(Suppl 2):S94-106.
  • 22. Brown WJ. Microbiology of the infected total joint arthroplasty. Semin Arthroplasty 1994;5(3):107-13.
  • 23. Bulut O, Öztemür Z. Ortopedik travmatolojik cerrahide antibiyotik proflaksisi. Cumhuriyet Üniversitesi Tıp Fakültesi Dergisi 2002;24(2):97-100.
  • 24. Tai CC, Nirvani AA, Holmes A, Hughes SP. Methicillinresistant Staphylococcus aureus in orthopaedic surgery. Int Orthop 2004;28(1):32-5.
  • 25. Akhan SÇ, Özsüt H, Eraksoy H, Hamzaoğlu A, Dilmener M, Çalangu S. Ortopedik yabancı cisim ve protez infeksiyonları. Klimik Dergisi 2000;13(3):88-90.
  • 26. David TS, Vrahas MS. Perioperative lower urinary tract infections and deep sepsis in patients undergoing total joint arthroplasty. J Am Acad Orthop Surg 2000;8(1):66-74.
  • 27. Glynn MK, Sheehan JM. The significance of asymptomatic bacteriuria in patients undergoing hip/knee arthroplasty. Clin Orthop Relat Res 1984;185:151-4.
  • 28. Ahnfelt L, Herberts P, Malchau H, Andersson GB. Prognosis of total hip replacement. A Swedish multicenter study of 4664 revisions. Acta Orthop Scand 1990;238(Suppl):l-26.
  • 29. Maderazo EG, Judson S, Pasternak H. Late infections of total joint prostheses: a review and recommendations for prevention. Clin Orthop Relat Res 1988;229:131-42.
  • 30. Saleh K, Olson M, Resig S, Bershadsky B, Kuskowski M, Gioe T, et al. Predictors of wound infection in hip and knee joint replacement: results from a 20 year surveillance program. J Orthop Res 2002;20(3):506-15.
  • 31. Wymenga AB, van Horn JR, Theeuwes A, Muytjens HL, Slooff TJ. Perioperative factors associated with septic arthritis after arthroplasty. Prospective multicenter study of 362 knee and 2,651 hip operations. Acta Orthop Scand 1992;63(6):665-71.
  • 32. Irvine R, Johnson BL Jr, Amstutz HC. The relationship of genitourinary tract procedures and deep sepsis after total hip replacements. Surg Gynecol Obstet 1974;139(5):701-6.
  • 33. Ritter MA, Fechtman RW. Urinary tract sequelae: possible influence on joint infections following total joint replacement. Orthopedics 1987;10(3):467-9.
There are 33 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Ahmet Aslan This is me

Remzi Arif Özerdemoğlu This is me

Fazıl Cüneyt Aydoğan This is me

Hüseyin Yorgancıgil This is me

Özgür Karakoyun This is me

Publication Date March 1, 2012
Published in Issue Year 2012 Volume: 18 Issue: 2

Cite

APA Aslan, A., Özerdemoğlu, R. A., Aydoğan, F. C., Yorgancıgil, H., et al. (2012). Kalça kırığı ve koksartrozda piyüri. Gaziantep Medical Journal, 18(2), 66-71.
AMA Aslan A, Özerdemoğlu RA, Aydoğan FC, Yorgancıgil H, Karakoyun Ö. Kalça kırığı ve koksartrozda piyüri. Gaziantep Medical Journal. March 2012;18(2):66-71.
Chicago Aslan, Ahmet, Remzi Arif Özerdemoğlu, Fazıl Cüneyt Aydoğan, Hüseyin Yorgancıgil, and Özgür Karakoyun. “Kalça kırığı Ve Koksartrozda piyüri”. Gaziantep Medical Journal 18, no. 2 (March 2012): 66-71.
EndNote Aslan A, Özerdemoğlu RA, Aydoğan FC, Yorgancıgil H, Karakoyun Ö (March 1, 2012) Kalça kırığı ve koksartrozda piyüri. Gaziantep Medical Journal 18 2 66–71.
IEEE A. Aslan, R. A. Özerdemoğlu, F. C. Aydoğan, H. Yorgancıgil, and Ö. Karakoyun, “Kalça kırığı ve koksartrozda piyüri”, Gaziantep Medical Journal, vol. 18, no. 2, pp. 66–71, 2012.
ISNAD Aslan, Ahmet et al. “Kalça kırığı Ve Koksartrozda piyüri”. Gaziantep Medical Journal 18/2 (March 2012), 66-71.
JAMA Aslan A, Özerdemoğlu RA, Aydoğan FC, Yorgancıgil H, Karakoyun Ö. Kalça kırığı ve koksartrozda piyüri. Gaziantep Medical Journal. 2012;18:66–71.
MLA Aslan, Ahmet et al. “Kalça kırığı Ve Koksartrozda piyüri”. Gaziantep Medical Journal, vol. 18, no. 2, 2012, pp. 66-71.
Vancouver Aslan A, Özerdemoğlu RA, Aydoğan FC, Yorgancıgil H, Karakoyun Ö. Kalça kırığı ve koksartrozda piyüri. Gaziantep Medical Journal. 2012;18(2):66-71.