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            <front>

                <journal-meta>
                                                                <journal-id>genel tıp derg</journal-id>
            <journal-title-group>
                                                                                    <journal-title>Genel Tıp Dergisi</journal-title>
            </journal-title-group>
                                        <issn pub-type="epub">2602-3741</issn>
                                                                                            <publisher>
                    <publisher-name>Selcuk University</publisher-name>
                </publisher>
                    </journal-meta>
                <article-meta>
                                        <article-id/>
                                                                                                                                                                                            <title-group>
                                                                                                                        <article-title>Schwannom; 10 yıllık tek merkez deneyimi</article-title>
                                                                                                                                                                                                <trans-title-group xml:lang="en">
                                    <trans-title>Schwannoma; 10 year single center experience</trans-title>
                                </trans-title-group>
                                                                                                    </title-group>
            
                                                    <contrib-group content-type="authors">
                                                                        <contrib contrib-type="author">
                                                                <name>
                                    <surname>Karanis</surname>
                                    <given-names>Meryem İlkay Eren</given-names>
                                </name>
                                                                    <aff>Konya Eğitim ve Araştırma Hastanesi, Tıbbi Patoloji Kliniği, Konya</aff>
                                                            </contrib>
                                                                                </contrib-group>
                        
                                        <pub-date pub-type="pub" iso-8601-date="20200601">
                    <day>06</day>
                    <month>01</month>
                    <year>2020</year>
                </pub-date>
                                        <volume>30</volume>
                                        <issue>2</issue>
                                        <fpage>92</fpage>
                                        <lpage>97</lpage>
                        
                        <history>
                                            </history>
                                        <permissions>
                    <copyright-statement>Copyright © 1990, Genel Tıp Dergisi</copyright-statement>
                    <copyright-year>1990</copyright-year>
                    <copyright-holder>Genel Tıp Dergisi</copyright-holder>
                </permissions>
            
                                                                                                <abstract><p>Amaç: Schwannomlar, Schwann hücrelerinden köken alan benign periferik sinir kılıfı tümörleridir.Sıklıkla asemptomatik, yavaş büyüyen, gerçek kapsülle çevrili, kesit yüzü pembe, beyaz-sarı renkli, genellikle küçük tümörlerdir.  Bu çalışmanın amacı schwannomların görülme yaşı, cinsiyet, boyut, yerleşim yeri gibi özelliklerini ortaya koymak ve bu özellikler  arasındaki ilişkiyi araştırmaktır.  Gereç ve Yöntem: Konya Eğitim ve Araştırma Hastanesi Patoloji Kliniği’nde 2008-2018 yılları arasında schwannom tanısı alan hastaların verileri retrospektif olarak incelendi.  Bulgular: Olguların yaş ortalaması 41.25±18.4’dür. Schwannomlar ortalama 2.96±2.1 cm çapındadır. 101 olgunun 51’i erkek, 50’si kadındır. Olguların 76’sında  %75.3  tümör dermal ve subkutan, 11’inde  %10.9  mediastinal, 11’inde  %10.9  intraabdominal, 3’ünde   %2.9  intrakranial ve spinal yerleşimlidir. Dermal ve subkutan schwannomlar DSS ’ın 39’u  %51.3  ekstremite, 22’si  %29  baş-boyun bölgesi, 15’i  %19.7  gövde yerleşimlidir. 97 olguda tümör soliter ve sporadiktir. İntraabdominal schwannomlar  İAS ’ın9’u   %81.8 kadın, 2’si  %18.2  erkektir. Ortalama tümör çapı DSS’da 2.32±1.58 cm, intrakraniyal ve spinal schwannomlar  İKSS da  3.40±0.79 cm, mediastinal schwannomlar MS ’da 5.26±2.28 cm, İAS’da 5.00±2.62 cm’dir. MS’lu bir olguda eksizyondan bir yıl sonra  tümör nüks etmiştir.  Sonuç: Schwannomlar en sık 5.dekatta, genellikle 5 cm’den küçük, sıklıkla dermal ve subkutan yerleşimli olarakekstremite ve baş-boyun bölgesinde, her iki cinsiyette eşit sıklıkta, büyük çoğunluğu soliter ve sporadik olarak izlendi. İAS kadınlarda daha sıktır. DSS,MS  ve İAS’lardan daha küçüktür. Nüks nadirdir.</p></abstract>
                                                                                                                                    <trans-abstract xml:lang="en">
                            <p>Objective: Schwannomas are benign peripheral nerve sheath tumors originating from Schwann cells. They can be seen at all ages, most common between the four and sixth decades. They are observed equally in men and women. 90% are solitary and sporadic. Schwannomas are mostly seen in the dermal and subcutaneous  DS  tissues, often in the extremities and head and neck region  HNR . They also appear as mediastinal, retroperitoneal, spinal, intracranial and visceral tumour.Material and Methods: Patients who were diagnosed as schwannoma in the Pathology Department of Konya Training and Research Hospital between October 1 2008 and October 1 2018 were retrospectively scanned.Results: The mean age of the patients was 41.25+18.4 years. Schwannomas have a mean diameter of 2.96+2.1 cm. Of 101 cases, 51 were male and 50 were female. 76 75.3%  tumors were DS, 11 10.9%  were mediastinal, 11 10.9%  were intraabdominal and 3 2.9%  were intracranial and spinal. Of the DS schwannomas, 39 51.3%  had extremity, 22 29%  had HNR, 15 19.7%  had trunk localisation. 11 schwannomas were cystic. In three cases, tumors were multiple. A mediastinal schwannoma recurred after one year from excision. No malignant transformation was observed in any of our cases.Conclusion: Schwannomas are mostly seen between the ages of 20-50 years in the extremities and HNR as DS tumours. In general, schwannomas are equal in both sexes. Intraabdominal schwannomas are more common in women. Schwannomas are usually smaller than 5 cm. DS schwannomas are smaller than mediastinal and intraabdominal schwannomas. Cystic schwannomas can be observed in cervical, mediastinal and retroperitoneal regions</p></trans-abstract>
                                                            
            
                                                            <kwd-group>
                                                    <kwd>Schwannom</kwd>
                                                    <kwd>   kistik schwannom</kwd>
                                                    <kwd>   sinir kılıfı tümörü</kwd>
                                            </kwd-group>
                                                        
                                                                            <kwd-group xml:lang="en">
                                                    <kwd>Schwannoma</kwd>
                                                    <kwd>   cystic schwannoma</kwd>
                                                    <kwd>   nerve sheath tumor</kwd>
                                            </kwd-group>
                                                                                                            </article-meta>
    </front>
    <back>
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