genel tıp derg

Genel Tıp Dergisi

2602-3741

Selcuk University

Yoğun Bakımdaki Kritik Hastalarda Akut Böbrek Hasarında Renal Replasman Tedavisi Kararı ve Zamanlaması

Kara

Iskender

Selçuk Üniversitesi, Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Konya Yıldırım

Fatma

Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi, Cerrahi Yoğun Bakım Ünitesi, Ankara Türkoğlu

Melda

Gazi Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Ankara Aygencel

Gülbin

Gazi Üniversitesi, Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Ankara

01 01 2019

29 1 37 47

1990

Genel Tıp Dergisi

Yoğun bakım ünitelerinde YBÜ takip edilen kritik hastalarda gelişen akut böbrek hasarı ABH önemli bir morbidite ve mortalite nedenidir. Bu hastalarda yapılan renal replasman tedavilerinin RRT başlatılmasında hangi kriterlerin kullanılacağı ve tedavinin ne zaman başlatılacağı soruları net olarak cevaplanmış değildir. Bu derlemede YBÜ’de RRT başlangıcını belirleyen faktörler incelendi. Ayrıca hastaların üre-kreatinin seviyeleri, idrar çıkışı-sıvı yükü, YBÜ yatışı ile RRT başlangıcı arasında geçen süre, prognostik faktörler ve bazı belirteçlere göre başlatılan erken ve geç RRT çalışmaları incelendi. Sonuçta YBÜ’de kritik hastalarda RRT başlangıcını belirleyen kriterler ve bu kriterlerin eşik değerlerinin kişiselleştirilmesi gerektiği düşünüldü

Acute kidney injury AKI developing in intensive care units ICU is an important cause of morbidity and mortality. The answers to the questions of which criteria are to be used in the initiation of and when to start renal replacement therapies RRT in those patients are not clear yet. In this review, urea and creatinine levels, urinary output and fluid load, duration between ICU admission and initiation of RRT, prognostic scores, and some RRT studies that were started early or late according to some markers were evaluated. In conclusion, the criteria to be used in the initiation of RRT in ICUs and the threshold levels of those criteria should be individualized

Renal replasman tedavileri zamanlama yoğun bakım ünitesi akut böbrek yetmezliği

Renal replacement therapy timing ıntensive care unit acute renal ınjury

Gupta S. Review Article. When to initiate RRT in patients with AKI-Does timing matter? Apollo Medicine 2013; 10: 41-6.

Bagshaw SM, Uchino S, Bellomo R, et al. For the Beginning and Ending Supportive Therapy for the Kidney (BEST Kid- ney) Investigators. Timing of renal replacement therapy and clinical outcomes in critically ill patients with severe acute kidney injury. Journal of Critical Care 2009; 24: 129–40.

Leung AKH, Yan WW. Review Article. Renal replacement therapy in critically ill patients. Hong Kong Med J 2009; 15: 122-9.

Uchino S. The epidemiology of acute renal failure in the world. Curr Opin Crit Care 2006; 12: 538-43.

Mendonca AD, Vincent JL, Suter PM, et al. Acute renal fa- ilure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med 2000; 26: 915-21.

Kellum JA, Bellomo R, Ronco C. Definition and classifica- tion of acute kidney injury. Nephron Clin Pract 2008; 109: 182-7.

Karvellas CJ, Farhat MR, Sajjad I, et al. A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis. Critical Care 2011; 15: R72.

Leite TT, Macedo E, Pereira SM, et al. Timing of renal rep- lacement therapy initiation by AKIN classification system. Critical Care 2013; 17: R62.

Bagshaw SM, Wald R, Barton J, et al. Clinical factors asso- ciated with initiation of renal replacement therapy in criti- cally ill patients with acute kidney injury—A prospective multicenter observational study. Journal of Critical Care 2012; 27: 268–75.

Drummond AD, Bellamy MC. Renal replacement therapy in the intensive care unit. Current Anaesthesia Critical Care 2010; 21: 69–74.

John S, Eckardt KU. Renal Replacement Strategies in the ICU. Chest 2007; 132: 1379–88.

John S, Eckardt KU. Renal Replacement Therapy in the Tre- atment of Acute Renal Failure-Intermittent and Continu- ous. Seminars in Dialysis 2006: 19: 455–64.

Matson J, Zydney A, Honore PM. Blood filtration: new op- portunities and the implications of systems biology. Crit Care Resusc 2004; 6: 209-17.

Clark E, Wald R, Walsh M, Bagshaw SM. Timing of initia- tion of renal replacement therapy for acute kidney injury: a survey of nephrologists and intensivists in Canada. Nephrol Dial Transplant 2012; 27: 2761–7.

Ricci Z, Ronco C. Timing, dose and mode of dialysis in acu- te kidney injury. Current Opinion in Critical Care 2011; 17: 556– 61.

Palevsky PM. Indications and timing of renal replacement therapy in acute kidney injury. Crit Care Med 2008; 36: 224–8.

Macedo E, and Mehta RL. Timing of Dialysis Initiation in Acute Kidney Injury and Acute-On-Chronic Renal Failure. Seminars in Dialysis 2013; 26: 675–81.

Smith OM, Wald R, Adhikari NKJ, Pope K, Weir MA, Ba- gshaw SM, on behalf of the Canadian Critical Care Trials Group. Standard versus accelerated initiation of renal rep- lacement therapy in acute kidney injury (STARRT-AKI): study protocol for a randomized controlled trial. Trials 2013; 14: 320.

Gibney N, Hoste E, Burdmann EA, et al. Timing of initia- tion and discontinuation of renal replacement therapy in AKI: unanswered key questions. Clin J Am Soc Nephrol 2008; 3: 876-80.

Ricci Z, Ronco C, D'Amico G, et al. Practice patterns in the management of acute renal failure in the critically ill patient: an international survey. Nephrol Dial Transplant 2006; 21: 690-6.

Overberger P, Pesacreta M, Palevsky PM. Management of renal replacement therapy in acute kidney injury: a survey of practitioner prescribing practices. Clin J Am Soc Neph- rol 2007; 2: 623-30.

Parsons FM, Hobson SM, Blagg CR, Mc CB. Optimum time for dialysis in acute reversible renal failure. Description and value of an improved dialyser with large surface area. Lan- cet 1961; 1: 129-34.

Wu VC, Ko WJ, Chang HW, et al. Early renal replacement therapy in patients with postoperative acute liver failure associated with acute renal failure: effect on postoperative outcomes. J Am Coll Surg 2007; 205: 266-76.

Carl DE, Grossman C, Behnke M, Sessler CN, Gehr TW: Effect of timing of dialysis on mortality in critically ill, sep- tic patients with acute renal failure. Hemodial Int 2010; 14: 11-7.

Tsai H, Wu VC, Yang M, et al. Outcome in acute liver failu- re patients treated with renal replacement therapy for acute renal failure: comparison between early or late dialysis. J Am Soc Nephrol 2005; 16: 541A.

Gettings LG, Reynolds HN, Scalea T. Outcome in post-tra- umatic acute renal failure when continuous renal replace- ment therapy is applied early vs. late. Intensive Care Med 1999; 25: 805-13.

Liu KD, Himmelfarb J, Paganini EP, et al. Timing of initi- ation of dialysis in critically ill patients with acute kidney injury. CJASN 2006; 1: 915-9.

Ostermann M, Chang RWS. Correlation between parame- ters at initiation of renal replacement therapy and outco- me in patients with acute kidney injury. Crit Care2009; 13: R175.

Sakr Y, Vincent JL, Reinhart K, et al. High tidal volume and positive fluid balance are associated with worse outcome in acute lung injury. Chest 2005; 128: 3098–108.

Uchino S, Bellomo R, Morimatsu H, et al. Pulmonary artery catheter versus pulse contour analysis: a prospective epide- miological study. Crit Care 2006; 10: R174.

Payen D, de Pont AC, Sakr Y, et al. A positive f luid balance is associated with a worse outcome in patients with acute renal failure. Crit Care 2008; 12: R74.

Bouchard J, Soroko SB, Chertow GM, et al. Fluid accumu- lation, survival and recovery of kidney function in critically ill patients with acute kidney injury. Kidney Int. 2009; 76: 422.

Wiedemann HP, Wheeler AP, Bernard GR, et al. Compa- rison of two fluid-management strategies in acute lung in- jury. N Engl J Med 2006; 354: 2564–75.

Demirkilic U, Kuralay E, Yenicesu M, et al. Timing of repla- cement therapy for acute renal failure after cardiac surgery. J Card Surg 2004; 19: 17-20.

Manche A, Casha A, Rychter Jet al. Early dialysis in acu- te kidney injury after cardiac surgery. Interact Cardiovasc Thorac Surg 2008; 7: 829–32.

Sugahara S, Suzuki H. Early start on continuous hemodi- alysis therapy improves survival rate in patients with acute renal failure following coronary bypass surgery. Hemodial Int 2004; 8: 320–5.

Ji Q, Mei Y, Wang X, et al. Timing of continuous veno-ve- nous hemodialysis in the treatment of acute renal failure following cardiac surgery. Heart Vessels 2011; 26: 183–9.

Elahi MM, Lim MY, Joseph RN et al. Early hemofiltration improves survival in post-cardiotomy patients with acute renal failure. Eur J Cardiothorac Surg 2004; 26: 1027–31.

Iyem H, Tavli M, Akcicek F, et al. Importance of early di- alysis for acute renal failure after an open-heart surgery. Hemodial Int 2009; 13: 55–61.

Bouman CS, Oudemans-Van SHM, Tijssen JG et al. Effects of early high-volume continuous veno-venous hemofiltra- tion on survival and recovery of renal function in intensive care patients with acute renal failure: a prospective, rando- mized trial. Crit Care Med 2002; 30: 2205–211.

Barbar SD, Binquet C, Monchi M, Bruyère R and Quenot JP. Impact on mortality of the timing of renal replacement therapy in patients with severe acute kidney injury in sep- tic shock: the IDEAL-ICU study (initiation of dialysis early versus delayed in the intensive care unit): study protocol for a randomized controlled trial. Trials 2014; 15: 270.

Piccinni P, Dan M, Barbacini S et al. Early isovolaemic hae- mofiltration in oliguric patients with septic shock. Intensive Care Med 2006; 32: 80–6.

Vaara ST, Reinikainen M, Wald R, Bagshaw SM, Pettila V and The FINNAKI Study Group. Timing of RRT Based on the Presence of Conventional Indications. Clin J Am Soc Nephrol 2014;9:1577-85.

Zarbock A, Kellum JA, Schmidt C, et al. Effect of Early vs Delayed Initiation of Renal Replacement Therapy on Mor- tality in Critically Ill Patients With Acute Kidney Injury.The ELAIN Randomized Clinical Trial. JAMA ;315:2190-9.

Wald R, Adhikari NKJ, Smith OM et al. Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury. Kidney International 2015, 88; 897–904.

Shiao CC, Wu VC, Li WY et al. Late initiation of renal rep- lacement therapy is associated with worse outcomes in acu- te kidney injury after major abdominal surgery. Crit Care 2009; 13: R171

Chou YH, Huang TM, Wu VC et al. Impact of timing of renal replacement therapy initiation on outcome of septic acute kidney injury. Crit Care 2011; 15: R134

Kara I, Yildirim F, Kayacan E, Bilaloğlu B, Turkoglu M, Ay- gencel G. Importance of RIFLE (Risk, Injury, Failure, Loss, and End-Stage Renal Failure) and AKIN (Acute Kidney Injury Network) in Hemodialysis Initiation and Intensive Care Unit Mortality. Iran J Med Sci 2017;42:397-403.

Kleinknecht D, Jungers P, Chanard J, et al. Factors influen- cing immediate prognosis in acute renal failure, with spe- cial reference to prophylactic hemodialysis. Adv Nephrol Necker Hosp 1971; 1: 207-30.

Conger JD. A controlled evaluation of prophylactic dialy- sis in post-traumatic acute renal failure. J Trauma 1975; 15: 1056-63.

Kara I, Kucuk H, Karabıyık L, Katı I. Acute Renal Failure ın a Multıple Trauma Patient with Rhabdomyolysis. Journal of Anesthesia - JARSS 2014; 22: 176–9.

Cappi SB, Sakr Y, Vincent JL. Daily evaluation of organ function during renal replacement therapy in intensive care unit patients with acute renal failure. J Crit Care. 2006; 21: 179-83.

Shum HP, Chan KC, Kwan MC et al. Timing for initiation of continuous renal replacement therapy in patients with septic shock and acute kidney injury. Ther Apher Dial. 2013; 17: 305-10.

Constantin JM, Futier E, Perbet S et al. Plasma neutrophil gelatinase-associated lipocalin is an early marker of acute kidney injury in adult critically ill patients: A prospective study. Journal of Critical Care 2010; 25:176.e1-6.

Royakkers AA, Korevaar JC, Van Suijlen JD et al. Serum and urine cystatin C are poor biomarkers for acute kidney injury and renal replacement therapy. Intensive Care Med 2011; 37: 493-501.

Oppert M. Timing of renal replacement therapy in acu- te kidney injury. Minerva Urologica e Nefrologica 2016; 68:72-7.

Cruz DN, Cal MD, Garzotto F, et al. Plasma neutrophil ge- latinase-associated lipocalin is an early biomarker for acute kidney injury in an adult ICU population. Intensive Care Med 2010; 36: 444–51.

Perianayagam MC, Seabra VF, Tighiouart H et al. Serum cystatin for prediction of dialysis requirement or death in acute kidney injury: a comparative study. Am J Kidney Dis. 2009; 54: 1025-33.

Liu Y, Davari-Farid S, Arora P, Porhomayon J and Nader ND. Early Versus Late Initiation of Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury After Cardiac Surgery: A Systematic Review and Meta-a- nalysis. J Cardiothorac Vasc Anesth 2014;28:557-63.

Wierstra BT, Kadri S, Alomar S, et al. The impact of “ear- ly” versus “late” initiation of renal replacement therapy in critical care patients with acute kidney injury: a systematic review and evidence synthesis. Crit Care 2016;20:122.

Yang XM, Tu GW, Zheng JL, et al. A comparison of early versus late initiation of renal replacement therapy for acute kidney injury in critically ill patients: an updated systema- tic review and metaanalysis of randomized controlled trials. BMC Nephrol 2017;18:264.

Bhatt GC and Das RR. Early versus late initiation of renal replacement therapy in patients with acute kidney injury-a systematic review & metaanalysis of randomized controlled trials. BMC Nephrol 2017;18:78.

Mavrakanas TA, Aurian-Blajeni DE, Charytan DM. Early versus late initiation of renal replacement therapy in pa- tients with acute kidney injury: a meta-analysis of rando- mised clinical trials. Swiss Med Wkly 2017;147:w14507.