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ANİ İDİYOPATİK SENSÖRİNÖRAL İŞİTME KAYBINDA PROGNOSTİK FAKTÖRLERİN ANALİZİ

Year 2022, Volume: 32 Issue: 2, 132 - 137, 29.04.2022
https://doi.org/10.54005/geneltip.1012146

Abstract

Amaç: Ani idiyopatik sensörinöral işitme kaybı (AİSNİK) odyolojik acil bir durum olarak tanımlanır. AİSNİK’te prognozu etkileyen faktörlerle ilgili pek çok çalışma yapılmış olmasına rağmen henüz fikir birliği yoktur. Bu çalışmanın amacı AİSNİK olan hastalarda klinik ve odyolojik faktörlerin prognostik değerinin analiz edilmesidir.
Hastalar ve Yöntem: AİSNİK nedeniyle tedavi edilen 118’i erkek, 92’si kadın 210 hastanın verileri retrospektif olarak incelendi. Hastaların demografik verileri, odyometri bulguları, ek semptom ve hastalıkları kaydedildi. İşitme kaybının derecesi; saf ses odyometri testine göre hafif (26-40 dB), orta (41-55 dB), orta-şiddetli (56-70 dB), şiddetli (71-90 dB) ve derin (> 90 dB) olarak sınıflandırıldı. İşitme kaybının şekli saf ses odyometri testine göre inen tip, çıkan tip, çanak tip ve düz tip olarak belirlendi. Hastaların tedaviye başlama zamanına göre ilk 3 günde, 3-10 gün arası ve 10 günden sonra olacak şekilde üç gruba ayrıldı. Yaş, cinsiyet, odyometrik bulgular, ek semptom ve hastalıkların; tedavi öncesi ve tedavi sonrası işitme seviyesi ile işitme kazanç seviyesi üzerine etkileri değerlendirildi.
Bulgular: Hastaların yaşlarının medyan değeri 46.0 (18.0) yıl idi. Odyometrini tipine göre en sık düz tip odyogram (%54.8) olduğu görüldü. Düz tip odyogramlara sahip hastalarda işitme kaybı seviyesi daha yüksek iken işitme kazançlarının daha az olduğu tespit edildi. Şiddetli işitme kaybı olan hastalarda işitme kazancının daha fazla olduğu belirlendi (p < 0.05). Tedaviye başlama sürelerine göre tedavi öncesi ve tedavi sonrası işitme seviyelerinde anlamlı fark yoktu (sırasıyla p; 0.051 ve 0.409) ancak işitme kazanç seviyelerinde anlamlı fark olduğu tespit edildi (p = 0.005). İlk 3 günde tedaviye başlanan hastalarda işitme kazanç seviyesi 4-10 gün ve 10 günden sonra başlananlara göre daha fazla idi. Hastalarda cinsiyet, etkilenen kulak yönü, ek bulgu ve hastalıkların varlığına göre tedavi öncesi ve tedavi sonrası işitme seviyeleri ile işitme kazanç seviyelerinde anlamlı fark olmadığı görüldü.
Sonuç: Tedaviye erken başlamanın AİSNİK’te en önemli prognostik faktör olduğu görüldü. İşitme kayıplarında erken tanı ve tedavi için toplumun bilinçlendirilmesi AİSNİK nedeni ile oluşmuş sekelleri azaltacaktır.

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References

  • Byl FM. Sudden hearing loss: eight years’ experience and suggested prognostic table. Laryngoscope. 1984;94(5 Pt 1):647–61.
  • Shikowitz MJ. Sudden sensorineural hearing loss. Med Clin North Am. 1991;75(6):1239–50.
  • Chandrasekhar SS, Tsai Do BS, Schwartz SR, et al. Clinical Practice Guideline: Sudden Hearing Loss (Update). Otolaryngol Head Neck Surg. 2019;161(1_suppl):1-45.
  • Haberkamp TJ, Tanyeri HM. Management of idiopathic sudden sensorineural hearing loss. Am J Otol. 1999;20(5):587–92; discussion 593-595.
  • Lee HS, Lee YJ, Kang BS, et al. A clinical analysis of sudden sensorineural hearing loss cases. Korean J Audiol. 2014;18(2):69–75.
  • Shaia FT, Sheehy JL. Sudden sensori-neural hearing impairment: a report of 1,220 cases. Laryngoscope. 1976;86(3):389–98.
  • İnanli S, Polat Ş, Tutkun A, et al. Ani işitme kayıplı olgularımızda tedavi ve prognozun retrospektif analizi. Türk Otolarengoloji Arşivi. 2002;40(3):196–200.
  • Mattox DE, Simmons FB. Natural history of sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol. 1977;86(4 Pt 1):463–80.
  • Kaplan Y, Ulkumen B, Kanlikama M. Evaluation of prognostic factors in sudden hearing loss. J Kartal TR. 2012;23(2):84–90.
  • Fasano T, Pertinhez TA, Tribi L, et al. Laboratory assessment of sudden sensorineural hearing loss: A case-control study: Sudden Sensorineural Hearing Loss Etiology. The Laryngoscope. 2017;127(10):2375–81.
  • Saeki N, Kitahara M. Assessment of prognosis in sudden deafness. Acta Otolaryngol Suppl. 1994;510:56–61.
  • Chang NC, Ho KY, Kuo WR. Audiometric patterns and prognosis in sudden sensorineural hearing loss in southern Taiwan. Otolaryngol Head Neck Surg. 2005;133(6):916–22.
  • Hirano K, Ikeda K, Kawase T, et al. Prognosis of sudden deafness with special reference to risk factors of microvascular pathology. Auris Nasus Larynx. 1999;26(2):111–5.
  • Kuhn M, Heman-Ackah SE, Shaikh JA, et al. Sudden sensorineural hearing loss: a review of diagnosis, treatment, and prognosis. Trends Amplif. 2011;15(3): 91–105.
  • Kanzaki J, Taiji H, Ogawa K. Evaluation of hearing recovery and efficacy of steroid treatment in sudden deafness. Acta Otolaryngol Suppl. 1988;456: 31–6.
  • Cinamon U, Bendet E, Kronenberg J. Steroids, carbogen or placebo for sudden hearing loss: a prospective double-blind study. Eur Arch Otorhinolaryngol. 2001;258(9): 477–80.
  • Kasapoglu F, Tuzemen G, Ozmen A. Prognosis in Sudden Hearing Loss: Is it the Disease or the Treatment that Determines the Prognosis? Int. Adv. Otol. 2009;5(2): 187-194.
  • Moskowitz D, Lee KJ, Smith HW. Steroid use in idiopathic sudden sensorineural hearing loss. Laryngoscope. 1984;94(5 Pt 1): 664–6.
  • Bulğurcu S, Şahin B, Akgül G, et al. The Effects of Prognostic Factors in Idiopathic Sudden Hearing Loss. Int Arch Otorhinolaryngol. 2018;22(1): 33–7.
  • Ceylan A, Celenk F, Kemaloğlu YK, et al. Impact of prognostic factors on recovery from sudden hearing loss. J Laryngol Otol. 2007;121(11): 1035–40.
  • Edizer DT, Celebi O, Hamit B, et al. Recovery of Idiopathic Sudden Sensorineural Hearing Loss. Int Adv Otol. 2015;11(2): 122–6.
  • Xenellis J, Karapatsas I, Papadimitriou N, et al. Idiopathic sudden sensorineural hearing loss: prognostic factors. The Journal of Laryngology&Otology. 2006;120(9): 718–24.
  • Fetterman BL, Saunders JE, Luxford WM. Prognosis and treatment of sudden sensorineural hearing loss. Am J Otol. 1996;17(4): 529–36.
  • Lee HS, Lee YJ, Kang BS, et al. A clinical analysis of sudden sensorineural hearing loss cases. Korean J Audiol. 2014;18(2): 69–75.
  • Zadeh MH, Storper IS, Spitzer JB. Diagnosis and treatment of sudden-onset sensorineural hearing loss: a study of 51 patients. Otolaryngol Head Neck Surg. 2003;128(1): 92–8.
  • Cho C-S, Choi Y-J. Prognostic factors in sudden sensorineural hearing loss: a retrospective study using interaction effects. Braz J Otorhinolaryngol. 2013;79(4): 466–70.
  • Huy PTB, Sauvaget E. Idiopathic sudden sensorineural hearing loss is not an otologic emergency. Otol Neurotol. 2005;26(5): 896–902.
  • Danino J, Joachims HZ, Eliachar I, et al. Tinnitus as a prognostic factor in sudden deafness. Am J Otolaryngol. 1984;5(6): 394–6.
  • Nakashima T, Yanagita N. Outcome of sudden deafness with and without vertigo. Laryngoscope. 1993;103(10): 1145–9.
  • Weng S-F, Chen Y-S, Hsu C-J, et al. Clinical features of sudden sensorineural hearing loss in diabetic patients. Laryngoscope. 2005;115(9): 1676–80.
  • Ohinata Y, Makimoto K, Kawakami M, et al. Blood viscosity and plasma viscosity in patients with sudden deafness. Acta Otolaryngol. 1994;114(6): 601–7.

Analysis of Prognostic Factors in Sudden Idiopatic Sensorineural Hearing Loss

Year 2022, Volume: 32 Issue: 2, 132 - 137, 29.04.2022
https://doi.org/10.54005/geneltip.1012146

Abstract

Objective: Sudden idiopathic sensorineural hearing loss (SISHL) is defined as an audiological emergency and although many studies have been conducted on the factors affecting prognosis, there is no consensus yet. The aim of this study is to analyze the prognostic value of clinical and audiological factors in patients with SISHL.
Patients and Methods: The data of 210 patients, 118 male and 92 female, who were treated for SISHL, were analyzed retrospectively. Demographic data, audiometry findings, additional symptoms and diseases of the patients were recorded. Degree of hearing loss; were classified as mild (26-40 dB), moderate (41-55 dB), moderate-severe (56-70 dB), severe (71-90 dB) and deep (> 90 dB) according to pure tone audiometry test. The type of hearing loss was determined as descending type, ascending type, midfrequency type and flat type. The patients were divided into three groups as those who started treatment in the first 3 days, between 3-10 days and after 10 days. The effects of age, gender, audiometric findings, additional symptoms and diseases on pre-treatment hearing level, post-treatment hearing level and hearing gain levels were evaluated.
Results: The median age of the patients was 46.0 (18.0) years. The most common flat audiogram (54.8%) was seen in the patients. It was observed that patients with flat type audiograms had more hearing loss and less hearing gain. It was determined that hearing gain was higher in patients with severe hearing loss (p < 0.05). There was no significant difference in the pre-treatment and post-treatment hearing levels (p; 0.051 and 0.409, respectively) according to the treatment initiation time, but there was a significant difference in the hearing gain levels (p = 0.005). In patients who started treatment in the first 3 days, the gain was higher than those who started after 4-10 days and 10 days. It was observed that there was no significant difference in pre-treatment and post-treatment hearing levels and hearing gain levels according to gender, affected ear direction, additional findings and presence of diseases.
Conclusion: Early initiation of treatment was found to be the most important prognostic factor in SISHL. Raising public awareness for early diagnosis and treatment will reduce the sequelae that may occur due to SISHL.

Project Number

yok

References

  • Byl FM. Sudden hearing loss: eight years’ experience and suggested prognostic table. Laryngoscope. 1984;94(5 Pt 1):647–61.
  • Shikowitz MJ. Sudden sensorineural hearing loss. Med Clin North Am. 1991;75(6):1239–50.
  • Chandrasekhar SS, Tsai Do BS, Schwartz SR, et al. Clinical Practice Guideline: Sudden Hearing Loss (Update). Otolaryngol Head Neck Surg. 2019;161(1_suppl):1-45.
  • Haberkamp TJ, Tanyeri HM. Management of idiopathic sudden sensorineural hearing loss. Am J Otol. 1999;20(5):587–92; discussion 593-595.
  • Lee HS, Lee YJ, Kang BS, et al. A clinical analysis of sudden sensorineural hearing loss cases. Korean J Audiol. 2014;18(2):69–75.
  • Shaia FT, Sheehy JL. Sudden sensori-neural hearing impairment: a report of 1,220 cases. Laryngoscope. 1976;86(3):389–98.
  • İnanli S, Polat Ş, Tutkun A, et al. Ani işitme kayıplı olgularımızda tedavi ve prognozun retrospektif analizi. Türk Otolarengoloji Arşivi. 2002;40(3):196–200.
  • Mattox DE, Simmons FB. Natural history of sudden sensorineural hearing loss. Ann Otol Rhinol Laryngol. 1977;86(4 Pt 1):463–80.
  • Kaplan Y, Ulkumen B, Kanlikama M. Evaluation of prognostic factors in sudden hearing loss. J Kartal TR. 2012;23(2):84–90.
  • Fasano T, Pertinhez TA, Tribi L, et al. Laboratory assessment of sudden sensorineural hearing loss: A case-control study: Sudden Sensorineural Hearing Loss Etiology. The Laryngoscope. 2017;127(10):2375–81.
  • Saeki N, Kitahara M. Assessment of prognosis in sudden deafness. Acta Otolaryngol Suppl. 1994;510:56–61.
  • Chang NC, Ho KY, Kuo WR. Audiometric patterns and prognosis in sudden sensorineural hearing loss in southern Taiwan. Otolaryngol Head Neck Surg. 2005;133(6):916–22.
  • Hirano K, Ikeda K, Kawase T, et al. Prognosis of sudden deafness with special reference to risk factors of microvascular pathology. Auris Nasus Larynx. 1999;26(2):111–5.
  • Kuhn M, Heman-Ackah SE, Shaikh JA, et al. Sudden sensorineural hearing loss: a review of diagnosis, treatment, and prognosis. Trends Amplif. 2011;15(3): 91–105.
  • Kanzaki J, Taiji H, Ogawa K. Evaluation of hearing recovery and efficacy of steroid treatment in sudden deafness. Acta Otolaryngol Suppl. 1988;456: 31–6.
  • Cinamon U, Bendet E, Kronenberg J. Steroids, carbogen or placebo for sudden hearing loss: a prospective double-blind study. Eur Arch Otorhinolaryngol. 2001;258(9): 477–80.
  • Kasapoglu F, Tuzemen G, Ozmen A. Prognosis in Sudden Hearing Loss: Is it the Disease or the Treatment that Determines the Prognosis? Int. Adv. Otol. 2009;5(2): 187-194.
  • Moskowitz D, Lee KJ, Smith HW. Steroid use in idiopathic sudden sensorineural hearing loss. Laryngoscope. 1984;94(5 Pt 1): 664–6.
  • Bulğurcu S, Şahin B, Akgül G, et al. The Effects of Prognostic Factors in Idiopathic Sudden Hearing Loss. Int Arch Otorhinolaryngol. 2018;22(1): 33–7.
  • Ceylan A, Celenk F, Kemaloğlu YK, et al. Impact of prognostic factors on recovery from sudden hearing loss. J Laryngol Otol. 2007;121(11): 1035–40.
  • Edizer DT, Celebi O, Hamit B, et al. Recovery of Idiopathic Sudden Sensorineural Hearing Loss. Int Adv Otol. 2015;11(2): 122–6.
  • Xenellis J, Karapatsas I, Papadimitriou N, et al. Idiopathic sudden sensorineural hearing loss: prognostic factors. The Journal of Laryngology&Otology. 2006;120(9): 718–24.
  • Fetterman BL, Saunders JE, Luxford WM. Prognosis and treatment of sudden sensorineural hearing loss. Am J Otol. 1996;17(4): 529–36.
  • Lee HS, Lee YJ, Kang BS, et al. A clinical analysis of sudden sensorineural hearing loss cases. Korean J Audiol. 2014;18(2): 69–75.
  • Zadeh MH, Storper IS, Spitzer JB. Diagnosis and treatment of sudden-onset sensorineural hearing loss: a study of 51 patients. Otolaryngol Head Neck Surg. 2003;128(1): 92–8.
  • Cho C-S, Choi Y-J. Prognostic factors in sudden sensorineural hearing loss: a retrospective study using interaction effects. Braz J Otorhinolaryngol. 2013;79(4): 466–70.
  • Huy PTB, Sauvaget E. Idiopathic sudden sensorineural hearing loss is not an otologic emergency. Otol Neurotol. 2005;26(5): 896–902.
  • Danino J, Joachims HZ, Eliachar I, et al. Tinnitus as a prognostic factor in sudden deafness. Am J Otolaryngol. 1984;5(6): 394–6.
  • Nakashima T, Yanagita N. Outcome of sudden deafness with and without vertigo. Laryngoscope. 1993;103(10): 1145–9.
  • Weng S-F, Chen Y-S, Hsu C-J, et al. Clinical features of sudden sensorineural hearing loss in diabetic patients. Laryngoscope. 2005;115(9): 1676–80.
  • Ohinata Y, Makimoto K, Kawakami M, et al. Blood viscosity and plasma viscosity in patients with sudden deafness. Acta Otolaryngol. 1994;114(6): 601–7.
There are 31 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Original Article
Authors

Fatih Yüksel 0000-0003-3894-7948

Erkun Tuncer 0000-0002-3336-2118

Hilal Yücel 0000-0002-1855-3186

Ekrem Özsöz This is me 0000-0003-3123-7249

Sinan Kır This is me 0000-0003-1875-9982

Project Number yok
Publication Date April 29, 2022
Submission Date October 20, 2021
Published in Issue Year 2022 Volume: 32 Issue: 2

Cite

Vancouver Yüksel F, Tuncer E, Yücel H, Özsöz E, Kır S. Analysis of Prognostic Factors in Sudden Idiopatic Sensorineural Hearing Loss. Genel Tıp Derg. 2022;32(2):132-7.