Sjögren’s syndromes mother’s baby with neonatal lupus syndrome

Year 2012, Volume: 22 Issue: 2, 67 - 70, 01.01.2012

Adem Küçük Sinan Bağçacı İlknur Albayrak Ali Baykan Sami Küçükşen Küçükşen

Abstract

Objective: We aimed to present a baby developing neonatal lupus syndrome whose mother is Sjögren's syndrome. Case report: Neonatal lupus syndrome NLS develops due to transmission of maternal antibodies from a mother with autoimmun disorders like Sjögren’s syndrome and other disorders. Cardiac involvement occurs due to the transmission of anti-Ro/SSa and anti-La/SSb antibodies in patients. In this article, we presented a baby developing congenital heart block and treated successfully by constant pacemaker. Conclusion: The risk of NLS should be kept in mind during pregnancy in the women with anti-Ro/SSA and anti-La/SSB antibodypositive SS. When fetal bradycardia is detected heart block should be considered. Appropriate treatment in intrauterine and neonatal period should be planned

Keywords

Sjögren’s syndrome, neonatal lupus syndrome, cardiac involvement

Sjögren sendromlu annenin neonatal lupus sendromlu bebeği

Abstract

Amaç: Sjögren sendromlu annenin neonatal lupus sendromu gelişen bebeğini olgu olarak sunmayı amaçladık. Olgu sunumu: Neonatal lupus sendromu NLS , Sjögren Sendromu SS ve diğer otoimmün hastalığı olan annelerin bebeklerinde anti-Ro/SSA ve anti-La/SSB antikorlarının geçişine bağlı olarak başta kardiyak tutulum oluşur. Bu yazıda SS’li annenin konjenital kalp bloğu tanısı alan ve kalıcı kalp pili uygulaması ile başarılı bir şekilde tedavi edilen NLS’li bebeği vaka olarak sunulmuştur. Sonuç: Anti-Ro/SSA ve anti-La/SSB antikoru pozitif SS gibi hastalığı olan kadınlarda gebelik boyunca NLS riski mutlaka akılda tutulmalı, fetal bradikardi saptandığında kalp bloğu akla gelmeli, intrauterin ve neonatal dönemde uygun tedavi planlanmalıdır

Keywords

Sjögren sendromu, neonatal lupus sendromu, kalp tutulumu

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