Çocuk ve adölosanlarda yaş, cinsiyet ve mevsimsel özelliklere göre vitamin D düzeylerinin değerlendirilmesi

Year 2022, Volume: 32 Issue: 4, 405 - 409, 31.08.2022

Esma Keleş Alp , Sema Mirza

https://doi.org/10.54005/geneltip.1098363

Cited By: 1

Abstract

Amaç: D vitamini, kas-iskelet sistemi sağlığı için gerekli bir hormondur ve bağışıklık sistemi, kardiyovasküler sistem ve metabolik homeostazda görev yapar. Bu çalışmanın amacı, Türkiye'nin orta bölgesinde yaşayan çocukların D vitamini durumunu belirlemektir. Ayrıca, çalışma yaş, cinsiyet ve mevsimsel değişiklikleri değerlendirdi.
Gereç ve Yöntem: Bu çalışmaya Konya’da ikinci basamak bir Kadın Doğum ve Çocuk Hastanesi’ne başvuran 1-17 yaş arası çocuklar dahil edildi. Katılımcıların tıbbi kayıtları Temmuz 2016 ve Aralık 2021 tarihleri arasında geriye dönük olarak hastane bilgi sisteminden incelendi. Tüm hastalar yaş, cinsiyet ve kanlarının alındığı mevsime göre kategorize edildi.
Bulgular: Toplam 3547 çocuk çalışmaya dahil edildi. Çalışma popülasyonundaki ortalama serum 25-hidroksivitamin D düzeyi 16.45±9.39 ng/ml idi. Kış aylarında elde edilen örnek sayısı sırasıyla 1063 (%30) ve yaz aylarında 756 (%21,3) olmuştur. Katılımcıların sadece %7.4'ü (n=262) çalışma popülasyonunda yeterli D vitamini düzeyine (>30 ng/ml) sahipti. Ayrıca şiddetli serum 25-hidroksivitamin D düzeyi eksikliği en çok kış mevsiminde ölçüldü (378 hasta, %45). Şiddetli eksiklik (352 hasta, %41.9) en yaygın olarak 12-17 yaş arası çocuklarda görüldü. Tüm hastalar arasında sadece %7.4'ünde yeterli serum 25-hidroksivitamin D seviyeleri vardı. Ayrıca, kızların %5,2'si (103 hasta) ve erkeklerin %3,7'si (59 hasta) yeterli 25-hidroksivitamin D düzeyine sahipti. Diğer taraftan, serum 25-hidroksivitamin D düzeylerinin ciddi eksikliği, kızlardan (137 hasta, %6.9) daha çok erkek çocuklarda (521 hasta, %33.1) yaygındı.
Sonuç: D vitamini eksikliği/yetersizliği dünyada ve Türkiye'de çocuklar arasında yaygın olarak görülmektedir. Çalışmamız mevsimsel farklılıklar, yaş ve cinsiyetin çocuklarda 25-hidroksivitamin D serum düzeylerini etkilediğini ortaya koydu. Bu bağlamda D vitamini yönünden zengin besinlerin veya D vitamini takviyesinin önemi giderek artmaktadır.

Keywords

Vitamin D, çocuk, adölosan, yaş, mevsimsel farklılık, tedavi

Evaluation of Vitamin D Levels According to Age, Gender and Seasonal Characteristics in Children and Adolescents

Abstract

Objective: Vitamin D is an essential hormone for the health of the musculoskeletal system and acts in immune system, cardiovascular system and metabolic homeostasis. The aim of this study was to determine the vitamin D status of children in middle region of Turkey. Also, the study evaluated the age, gender and seasonal variations in the study population.
Materials and Methods: Children aged 1-17 years who were admitted to a Secondary Maternity and Children Hospital in Konya were included in this study. The medical records of the participants were retrospectively evaluated from the hospital information system between July 2016 and December 2021. All patients were categorized according to age, gender, and season in which their blood had been sampled.
Results: A total of 3547 children were included in the study. The mean serum level of 25-hydroxyvitamin D in the study population was 16.45±9.39 ng/ml. The number of samples obtained in winter was 1063 (30%) and in summer 756 (21.3%), respectively. Only 7.4% (n=262) of the participants had sufficient vitamin D levels (>30 ng/ml) in the study population. Additionally, severely deficiency of serum 25-hydroxyvitamin D level was mostly measured in winter season (378 patients, 45%). Severely deficiency (352 patients, 41.9%) was most common in children aged 12-17 years. Among all patients, only 7.4% had sufficient serum 25-hydroxyvitamin D levels. Also, 5.2% (103 patients) of the girls and 3.7% (59 patients) of the boys had sufficient 25-hydroxyvitamin D levels. On the other hand, severely deficiency of serum 25-hydroxyvitamin D levels was most common in boys (521 patients, 33.1%) than in girls (137 patients, 6.9%).
Conclusion: Vitamin D deficiency/insufficiency is wide spread among children in the world and in Turkey. Our study revealed that seasonal variations, age and gender affect the serum levels of 25-hydroxyvitamin D in children. In this context, the importance of vitamin D rich foods or vitamin D supplementation is increasing.

Keywords

Vitamin D, children, adolescents, age, seasonal variations, treatment

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