Abstract
Giriş: Mukoepidermoid karsinom tükrük bezlerinin sık görülen malignitelerinden biridir. Nazofarengeal yerleşim gösteren mukoepidermoid karsinom vakaları nadir görülür. Nadir görülen bu olguların tedavisi tümörün evresi ve çevre dokulara invazyonuna göre şekillenir.
Olgu: 63 yaşında erkek hasta 2006 yılında tiroid papiller karsinom nedeni ile takipli hastanın tıbbi onkoloji takiplerinde insidental olarak beyin MR sonucunda nazofarenkste solda asimetrik kalınlaşma saptanması üzerine kliniğimize sevk edildi. Hastanın sol boyun bölgesinde yaklaşık bir aydır olan ağrı şikayeti mevcuttu. PET/CT de sol jugulodigastrik bölgede artmış FDG tutulumuna sahip lenf nodundan eksizyonel biyopsi ve nazofarenksten multiple punch biyopsi yapıldı. Patoloji sonucu mukoepidermoid karsinom gelen hasta radyokemoterapi almak üzere onkolojiye sevk edildi.
Tartışma: Nazofarenkste kitle ile gelen hastalarda nadir de olsa mukoepidermoid karsinom olabileceği akılda tutulmalıdır. Günümüze kadar yapılan çalışmalarda tedavi seçenekleri hakkında bilgiler olsa da prognoz ve tedavi seçimi için prospektif çalışmalara ihtiyaç vardır.
References
- Ollero JM, Morón AH, Luis ÁM, Sánchez SM, Nazarewsky AA, López MJS, et al. Nasopharyngeal mucoepidermoid carcinoma: a case report and review of literature. Rep Pract Oncol Radiother 2013;18(2):117-20.
- Hemalatha A, HK SK, Geetanjali S, Giripunja M, Shashikumar S. Nasopharyngeal mucoepidermoid carcinoma-A common entity at an uncommon location. J Clin Diagn Res. 2014;8(1):164.
- Erdem RO Evaluation of the nasal cavity and paranasal sinuses. İnside: TOPUZ MF, editor. Kulak Burun Boğaz Hastalıklarına Giriş: Akademisyen Kitabevi; 2022, p 291-298.
- Erdem RO, Dundar MA, Arbag S, Arbag H, Seker M. Endoscopıc Anatomy of the Lacrımal Sac: A Cadaverıc Study. 2022.
- Erdem RO Visualization of the larynx. İnside: MÜDERRİS T, MUZ SE, KESİCİ GG, İSLAMOĞLU Y., editor. Kulak Burun Boğaz Hastalıklarında Temel Yaklaşım ve Yönetim: Akademisyen Kitabevi; 2020, p 483-490.
- Stewart FW, Foote FW, Becker WF. Muco-epidermoid tumors of salivary glands. Ann Surg. 1945;122(5):820.
- Bai S, Clubwala R, Adler E, Sarta C, Schiff B, Smith RV, et al. Salivary mucoepidermoid carcinoma: a multi-institutional review of 76 patients. Head Neck Pathol 2013;7:105-12.
- Qiu F, Hua YJ, Guo L, He JH, Qiu XL, Hong MH. Mucoepidermoid carcinoma of nasopharynx: a report of twelve cases. Ai Zheng. 2005;24(3):362-4.
- Zhang X-m, Cao J-z, Luo J-w, Xu G-z, Gao L, Liu S-y, et al. Nasopharyngeal mucoepidermoid carcinoma: a review of 13 cases. Oral Oncol 2010;46(8):618-21.
Abstract
Introduction : Mucoepidermoid carcinoma is one of the common malignancies of the salivary glands. Nasopharyngeal mucoepidermoid carcinoma cases are rare. The treatment of these rare cases depends on the stage of the tumor and its invasion into the surrounding tissues.
Case: A 63-year-old male patient, who was followed up for thyroid papillary carcinoma in 2006, was referred to our clinic after incidentally detected asymmetrical thickening of the nasopharynx on the left as a result of brain MRI during medical oncology follow-ups. The patient had a complaint of pain in the left neck region for about a month. Excisional biopsy from the lymph node that increased FDG uptake in the left jugulodigastric region in PET/CT and multiple punch biopsy from the nasopharynx were performed. The patient, whose pathology resulted in mucoepidermoid carcinoma, was referred to oncology to receive radiochemotherapy.
Discussion: Although rare, it should be kept in mind that in patients presenting with a mass in the nasopharynx, mucoepidermoid carcinoma may be present. Although there is information about treatment options in the studies carried out to date, prospective studies are needed for prognosis and treatment selection.
References
- Ollero JM, Morón AH, Luis ÁM, Sánchez SM, Nazarewsky AA, López MJS, et al. Nasopharyngeal mucoepidermoid carcinoma: a case report and review of literature. Rep Pract Oncol Radiother 2013;18(2):117-20.
- Hemalatha A, HK SK, Geetanjali S, Giripunja M, Shashikumar S. Nasopharyngeal mucoepidermoid carcinoma-A common entity at an uncommon location. J Clin Diagn Res. 2014;8(1):164.
- Erdem RO Evaluation of the nasal cavity and paranasal sinuses. İnside: TOPUZ MF, editor. Kulak Burun Boğaz Hastalıklarına Giriş: Akademisyen Kitabevi; 2022, p 291-298.
- Erdem RO, Dundar MA, Arbag S, Arbag H, Seker M. Endoscopıc Anatomy of the Lacrımal Sac: A Cadaverıc Study. 2022.
- Erdem RO Visualization of the larynx. İnside: MÜDERRİS T, MUZ SE, KESİCİ GG, İSLAMOĞLU Y., editor. Kulak Burun Boğaz Hastalıklarında Temel Yaklaşım ve Yönetim: Akademisyen Kitabevi; 2020, p 483-490.
- Stewart FW, Foote FW, Becker WF. Muco-epidermoid tumors of salivary glands. Ann Surg. 1945;122(5):820.
- Bai S, Clubwala R, Adler E, Sarta C, Schiff B, Smith RV, et al. Salivary mucoepidermoid carcinoma: a multi-institutional review of 76 patients. Head Neck Pathol 2013;7:105-12.
- Qiu F, Hua YJ, Guo L, He JH, Qiu XL, Hong MH. Mucoepidermoid carcinoma of nasopharynx: a report of twelve cases. Ai Zheng. 2005;24(3):362-4.
- Zhang X-m, Cao J-z, Luo J-w, Xu G-z, Gao L, Liu S-y, et al. Nasopharyngeal mucoepidermoid carcinoma: a review of 13 cases. Oral Oncol 2010;46(8):618-21.
Details
| Primary Language | English |
|---|---|
| Subjects | Clinical Oncology, Otorhinolaryngology |
| Journal Section | Case Report |
| Authors | |
| Early Pub Date | April 27, 2024 |
| Publication Date | April 30, 2024 |
| Submission Date | June 21, 2023 |
| Published in Issue | Year 2024 Volume: 34 Issue: 2 |
The Journal of General Medicine is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY NC).