Investigation of Reaction of Some Ester Ethoxycarbonyl Hydrazones with 1-Adamantyl Amine

Year 2019, Volume: 47 Issue: 2, 203 - 208, 18.09.2019

İnci Selin Doğan Hasan Erdinç Sellitepe Bahittin Kahveci

https://doi.org/10.15671/hjbc.623792

Abstract

I
n this study, the reactions of the 1-adamantyl amine with 4 different ester ethoxycarbonyl hydrazone derivatives were
studied. At first, iminoester hydrochloride derivatives were synthesized according to the Pinner method. Then they
were reacted with ethyl carbazate to synthesize ester ethoxycarbonyl hydrazone derivative compounds. In the last step,
3-substituted-4-adamantyl-1,2,4-triazol-5-one derivatives were aimed to synthesize, the ester ethoxycarbonyl hydrazone
compounds were heated in an oil bath dry to dry with 1-adamantyl amine. It has been observed, however, that the ring is
not closed according to IR and ¹H-NMR analysis and the ethyl N-(adamantylcarbamoyl)alkylcarbohydrazonoate derivative
compounds were synthesized as stabile and original compounds. The structures of the synthesized compounds were elucidated by spectroscopic methods using IR, ¹H-NMR, 13C-NMR spectra and LC/MS analysis.

Keywords

1-adamantyl amine, ester ethoxycarbonyl hydrazone, , iminoester hydrochlorides, Pinner method

Supporting Institution

TUBİTAK

Project Number

1919B011603783

Thanks

This study has been supported by Tübitak 2209A Project No. 1919B011603783 Support Program for Domestic Research Projects of University Students.

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